deTS Results for Job coding: chartered/certified accountant, auditor, company accountant, articled/audit clerk, official receiver

Traits Information:

Trait ID:

3366

22601_24213281
Job coding: chartered/certified accountant, auditor, company accountant, articled/audit clerk, official receiver
UK Biobank (UKBB)
Neale Lab, 2018
# cases = 1919 | # controls = 87947
# SNPs = 10380864 | # genes = 21889
1.002
p (gene) < 0.05:  # TAGs = 1130
p (gene) < 0.01:  # TAGs = 250
p (gene) < 0.001:  # TAGs = 39
p (gene) < 1.0E-4:  # TAGs = 2
p (gene) < 1.0E-5: # TAGs = 1

Manhattan Plot of All SNPs in the GWAS




Manhattan Plot of All Genes in the GWAS


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deTS Enrichment Analysis Using the GTEx Panel


p < 0.05 p < 0.01 p < 0.001 0.1950.02320.6930.4930.4930.4250.7520.8510.8510.8510.8510.920.1170.5620.920.4250.06520.08830.02320.6930.4250.1950.9850.1530.4930.1530.7520.360.8510.03340.2440.2990.5620.920.5620.08830.8890.06520.08830.08830.03270.4250.920.9620.6290.9620.8890.2480.50.9930.9930.9930.9380.9760.9930.7680.8690.9760.9930.9380.8690.9930.9760.7680.9380.2480.50.3650.9760.9380.8690.50.640.8690.640.9760.2481.00.9380.50.50.7680.09330.9380.640.002590.001060.1560.09330.7680.9380.7680.640.7680.1620.1620.7620.7621.01.01.01.01.01.01.01.01.01.01.01.01.01.00.4120.7620.4120.7621.00.4121.00.7620.7620.4121.00.4121.00.7620.4120.4120.1621.01.00.7625.43E-65.43E-60.7621.01.01.01.01.01.0Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel


p < 0.05 p < 0.01 p < 0.001 0.1670.03590.5970.5970.4570.2130.8720.8310.660.3890.1670.5270.7210.5970.05180.9370.09710.07160.3890.3250.09710.450.3890.01690.05080.4570.910.3890.8330.2130.9820.7270.5270.2630.7240.7240.2130.8760.7270.6640.9370.9370.9720.7840.7430.7421.00.610.3340.8530.6070.6080.6080.8530.2220.7430.8510.4680.7430.9720.8530.610.7430.3340.3340.3310.4680.1370.3320.4680.9720.9280.610.4680.9710.9920.3340.7420.9280.2217.63E-40.3340.610.610.7430.9920.9920.8530.3920.3921.01.01.00.3921.01.01.01.00.1490.3920.3910.3920.3921.00.7490.7490.7490.7490.7490.1481.01.00.3920.7490.7490.7490.3920.7490.7480.7491.00.7481.02.71E-43.48E-50.7491.00.7491.00.3920.7490.749Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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