deTS Results for Job coding: bank manager, bank section manager, building society manager, post/sub-post office manager

Traits Information:

Trait ID:

3409

22601_11513250
Job coding: bank manager, bank section manager, building society manager, post/sub-post office manager
UK Biobank (UKBB)
Neale Lab, 2018
# cases = 1293 | # controls = 88573
# SNPs = 9720038 | # genes = 21891
1.008
p (gene) < 0.05:  # TAGs = 1116
p (gene) < 0.01:  # TAGs = 225
p (gene) < 0.001:  # TAGs = 17
p (gene) < 1.0E-4:  # TAGs = 3
p (gene) < 1.0E-5: # TAGs = 1

Manhattan Plot of All SNPs in the GWAS




Manhattan Plot of All Genes in the GWAS


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deTS Enrichment Analysis Using the GTEx Panel


p < 0.05 p < 0.01 0.4620.02640.730.8780.9380.6010.4620.5320.9380.8780.7870.730.4620.5320.5320.7870.3940.6010.1320.1710.8360.6010.1320.8780.9380.4620.270.05340.270.05340.6680.730.3940.1320.2170.8360.9990.7870.6010.5320.5280.8780.730.9120.730.270.5320.6070.3140.6070.4540.4540.3140.4540.3140.8640.8640.750.6070.3140.6070.2010.6070.6070.3140.03270.2011.00.4540.4540.3140.8640.6070.4540.2010.4540.940.750.8640.1180.8640.3140.8640.9950.6070.750.4540.9990.940.750.9990.8640.3140.201Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel


p < 0.05 p < 0.01 0.9230.3340.5460.1330.6170.4040.8470.40.2730.5460.7470.1330.2150.8510.2760.1330.4040.6170.2210.4740.6170.7410.1730.2180.1310.5460.9650.00460.5460.6170.5390.8910.9870.8890.9960.80.4740.5460.8910.2760.9230.03691.54E-50.5460.8420.9750.8420.0250.8420.5660.9270.5650.5650.2770.5660.1710.05030.9940.09730.4130.05120.8420.09730.7170.4130.5630.2770.7150.9280.5660.9286.99E-40.5660.2770.9270.5660.9991.00.7150.7150.5660.2770.7170.8420.9940.09730.004780.0973Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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