deTS Results for Job coding: nursing auxiliary or assistant, steriliser of medical equipment, occupational therapy assistant, phlebotomist, physiotherapy assistant, ward orderly, ward assistant

Traits Information:

Trait ID:

3431

22601_61113073
Job coding: nursing auxiliary or assistant, steriliser of medical equipment, occupational therapy assistant, phlebotomist, physiotherapy assistant, ward orderly, ward assistant
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=22601
# cases = 1272 | # controls = 88594
# SNPs = 9693304 | # genes = 21887
0.996
p (gene) < 0.05:  # TAGs = 1087
p (gene) < 0.01:  # TAGs = 224
p (gene) < 0.001:  # TAGs = 34
p (gene) < 1.0E-4:  # TAGs = 3
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.9330.8250.8690.7740.6520.2040.3770.3130.5140.4440.5140.4440.2550.09180.5840.1220.09180.09180.3770.7740.9540.8690.2040.9540.8690.4440.7160.03430.160.7740.3770.8250.6520.3130.5140.9050.6520.8690.3770.3130.9530.4440.5840.8250.9330.6520.8690.9550.7930.3710.1530.3710.01080.04690.0880.01080.01080.04690.04690.04690.0880.3710.04690.02330.02330.9550.3710.9970.3710.5150.6620.7930.1530.5150.0880.5150.7930.5150.9550.5150.7930.9850.9550.7930.9850.7930.6620.8920.7930.8920.9850.8920.7930.9850.6230.6230.6230.2450.6230.06640.06640.2450.06640.06640.06640.06640.06640.2450.2450.2450.6230.6231.00.6231.00.6230.2450.6231.00.6230.6230.6230.6230.2450.6231.00.6231.01.01.00.6231.00.6230.6230.2451.01.01.00.6230.6231.0Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.7470.3340.3370.6840.9230.7470.7410.80.3340.2210.9230.7470.4670.6170.5460.01130.6170.2760.7470.4040.5460.3310.6170.8490.6130.8510.6840.8510.3370.9780.02430.4740.8510.9460.9227.47E-65.98E-40.5460.6170.9780.4740.2210.9780.8030.7410.3030.5960.7410.9370.4430.440.3030.3030.3040.9950.3040.3010.9370.5960.3040.3040.5960.1920.4430.5960.5930.3040.8580.740.7410.5960.5960.3040.8590.3010.9370.9370.8580.9791.09E-50.01420.3040.9370.9790.9370.5960.9370.9370.04250.1880.5591.01.00.1880.5580.5580.5580.1880.5591.01.01.01.00.006881.00.5590.5591.01.00.5580.5590.5580.04230.5591.01.01.01.00.5581.01.00.5581.00.5580.5591.01.01.01.00.1880.5590.559Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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