deTS Results for Job coding: estimator, valuer, building estimator/assessor, insurance assessor, costing engineer, surveyor/valuer, lottery officer, rating officer, marine/naval surveyor

Traits Information:

Trait ID:

3509

22601_35313264
Job coding: estimator, valuer, building estimator/assessor, insurance assessor, costing engineer, surveyor/valuer, lottery officer, rating officer, marine/naval surveyor
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=22601
# cases = 396 | # controls = 89470
# SNPs = 7757191 | # genes = 21890
1.027
p (gene) < 0.05:  # TAGs = 1339
p (gene) < 0.01:  # TAGs = 272
p (gene) < 0.001:  # TAGs = 50
p (gene) < 1.0E-4:  # TAGs = 3
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.9470.7720.7180.9250.9640.03350.1460.08560.4640.2820.06380.230.03350.4640.1850.04670.1460.3390.3390.8970.3390.8970.40.9760.40.8970.8970.4640.820.8970.9250.2820.530.6580.9250.1460.5950.230.530.5950.8180.230.1850.7720.8970.6580.40.8320.8320.5950.7230.5950.2260.2260.2260.7230.7230.1440.2260.1440.8320.460.2260.2260.3330.460.960.9860.5950.8320.7230.8320.960.960.9110.7230.9110.5950.5950.9110.5950.7230.9110.9990.5950.8320.8320.4580.7230.7230.9110.9860.8320.5950.8420.8421.01.01.00.8420.8420.8420.8420.8420.8420.8420.8420.8420.8420.8420.5430.8420.8421.00.8420.8421.00.8421.01.01.01.00.8421.01.00.8421.01.00.8420.5431.00.5430.8420.8421.01.01.01.01.01.01.0Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.6290.4910.7510.2480.4280.8490.7450.6890.4240.6930.4280.7510.5550.02450.9180.7510.8870.3630.7510.4280.5630.4870.9610.8850.2990.9970.9840.6930.4950.9740.9150.3030.1210.1190.8470.4240.3030.6930.1990.09120.9423.97E-80.6290.7510.3610.4940.7650.3610.4960.9370.9750.7630.8660.8670.09150.7650.4920.8670.4960.6360.1550.8670.4960.6360.6360.8650.7650.6340.9750.7650.8670.9370.6360.9370.7620.8670.9760.6340.7630.9750.3610.4960.8670.2450.8671.53E-160.4960.9760.8150.8151.00.2250.8150.8150.8140.8150.4940.8150.8150.4951.00.8150.8151.01.01.01.01.01.00.8140.8150.8151.01.00.8151.01.01.01.01.00.8151.00.4940.8150.2250.8151.00.4951.02.12E-180.8151.0Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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