deTS Results for Job coding: metal working machine operator, fettler, grinder, metal cutter, metal machinist, metal polisher, press operator, shot blaster, tool room machinist

Traits Information:

Trait ID:

3616

22601_81252835
Job coding: metal working machine operator, fettler, grinder, metal cutter, metal machinist, metal polisher, press operator, shot blaster, tool room machinist
UK Biobank (UKBB)
Neale Lab, 2018
# cases = 130 | # controls = 89736
# SNPs = 5657922 | # genes = 21834
1.022
p (gene) < 0.05:  # TAGs = 1112
p (gene) < 0.01:  # TAGs = 231
p (gene) < 0.001:  # TAGs = 33
p (gene) < 1.0E-4:  # TAGs = 5
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS




Manhattan Plot of All Genes in the GWAS


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deTS Enrichment Analysis Using the GTEx Panel


p < 0.05 p < 0.01 p < 0.001 0.2330.1850.8010.6860.7470.8480.7470.9190.5520.7470.8480.6860.9620.6860.8480.8880.8010.6860.2880.4140.2330.8880.2880.8010.6210.6860.2880.2880.4830.3490.8480.9620.8880.4140.3490.6860.4830.5520.7470.8010.1820.7470.3490.00590.4140.2880.4140.8110.6730.9110.9680.9680.6730.5160.9110.9680.9680.8110.5160.8110.3630.8110.8110.3630.1380.6730.1380.2340.6730.6730.8110.8110.8110.6730.9680.9110.6730.9680.9110.8110.07540.3630.6730.5160.3630.6730.6730.3610.9110.1380.5160.07540.5160.1381.01.00.371.01.00.07110.370.370.370.370.370.370.07110.07110.370.07110.07110.07111.01.00.371.01.01.01.00.371.01.01.01.01.01.01.01.01.01.00.370.370.370.370.3691.00.370.371.01.00.37Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel


p < 0.05 p < 0.01 p < 0.001 0.3780.5840.120.5170.6560.7210.870.7770.6530.5170.2030.8310.3710.3780.5880.2030.5170.2540.1580.2030.03290.3070.3780.310.310.3130.4460.990.8310.9570.2490.120.7210.4430.1560.1560.7210.8310.9090.2030.1580.4460.6560.3780.7650.7640.6110.8830.4480.7650.6090.9550.4460.2990.4480.9560.4450.4480.6110.4480.6110.4480.6110.02460.05210.7620.4480.1810.4460.6110.7650.9560.6110.9990.6090.05210.9560.2980.2980.610.2990.6110.8830.4480.7650.4480.7650.8831.01.01.01.00.3011.01.01.00.30.3011.01.01.00.3010.3011.00.3011.01.00.3010.3011.01.00.04390.31.01.01.01.01.01.01.01.00.31.00.30.3011.01.01.01.01.01.01.0Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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