deTS Results for Length of working week for main job

Traits Information:

Trait ID:

3889

767_irnt
Length of working week for main job
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=767
# cases = 0 | # controls = 202304
# SNPs = 13580562 | # genes = 21891
1.058
p (gene) < 0.05:  # TAGs = 1808
p (gene) < 0.01:  # TAGs = 451
p (gene) < 0.001:  # TAGs = 85
p (gene) < 1.0E-4:  # TAGs = 9
p (gene) < 1.0E-5: # TAGs = 1

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.890.9370.1070.08370.2061.5E-61.5E-62.15E-41.31E-42.71E-52.71E-58.89E-68.89E-67.85E-53.48E-41.31E-48.73E-41.56E-50.9160.8590.8220.8220.02690.8220.2950.6290.6290.9670.7340.7810.4570.7340.2060.7340.9540.8590.8590.5150.5150.5720.9530.9160.02690.4570.890.1350.5720.4770.870.08170.3690.3690.01610.08170.008580.1910.04980.1910.1280.01610.0290.04980.004380.3690.08170.3690.590.9620.6980.08170.590.1910.1280.2720.870.4770.9830.1910.2720.2720.590.9620.9260.7940.3690.590.590.9930.590.2720.1280.9260.3690.2720.4850.9310.1170.1170.04420.1170.1170.1170.2610.1170.2610.1170.2610.1170.4850.4850.2610.1170.4850.1170.9310.2610.7410.1170.4850.4850.2610.4850.004010.7410.2610.2610.7410.9310.9310.4850.9310.7410.7410.7411.01.00.2610.2610.7410.4850.741Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.9970.9220.4640.06330.1060.7440.07930.01810.2463.01E-40.8320.1680.7370.8680.9710.1680.9920.6930.7440.350.08270.5730.4640.2030.5770.8980.4060.5810.250.7910.8260.7910.7910.9710.5770.8650.7910.1060.5810.02590.5230.5230.7910.9230.6540.9070.1020.8440.5410.6540.5370.3190.5390.3210.230.3210.650.9520.6540.06310.8440.9780.3210.1570.03720.7540.4270.7560.4250.8440.1570.6540.3210.9780.2270.5410.7580.9970.3190.9510.6540.9080.1570.4270.4270.01130.8440.8440.7190.9220.4570.7190.1020.7190.03650.003030.03670.03690.9230.7190.2360.9230.1020.4570.1021.00.4570.2370.4570.7180.4570.1020.7180.4570.4570.4570.7191.00.7180.9230.2370.9220.9220.9220.7190.7190.9230.1020.4570.7190.7190.923Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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