deTS Results for Vitamin B6

Traits Information:

Trait ID:

4072

100012_irnt
Vitamin B6
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=100012
# cases = 0 | # controls = 51453
# SNPs = 13550187 | # genes = 21889
1.024
p (gene) < 0.05:  # TAGs = 1484
p (gene) < 0.01:  # TAGs = 316
p (gene) < 0.001:  # TAGs = 30
p (gene) < 1.0E-4:  # TAGs = 4
p (gene) < 1.0E-5: # TAGs = 1

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.9260.871.01.01.00.3390.2380.1950.05660.02220.3390.3390.3960.2380.1950.1250.1250.1570.6910.1950.1570.6350.7910.7910.9820.9620.9820.3390.7440.8340.870.5760.4550.9460.9740.7910.07480.09740.9620.870.5110.6910.09740.1570.9930.8340.5150.7550.6320.7550.7550.7550.1690.2590.06010.1040.1040.3710.50.1040.1040.06010.06010.1040.06010.03270.2590.3710.2590.9670.6320.9250.7550.9970.1040.9250.9970.2590.3710.9890.8540.2590.6320.003730.2590.9970.9890.1680.50.50.50.9670.9890.6320.7230.7230.3580.3580.7230.7230.7231.00.7230.3580.7230.7230.7230.3580.7231.00.3580.7230.7231.00.7230.7231.00.7231.01.01.00.7231.01.00.1270.7230.7231.00.3581.00.3580.3580.7230.7230.7220.7230.1270.7231.01.00.0339Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.9760.570.9760.7940.2310.5120.6270.3860.4470.150.6920.8370.1140.5740.9650.150.9050.9050.9490.7460.7940.3820.5120.9280.7910.390.6340.390.6340.4510.9930.5120.6340.1160.3860.9030.7940.8370.6340.3330.8740.390.7940.3330.2230.3280.720.5910.1410.2230.220.3280.140.2230.01220.720.220.9090.8290.8290.5910.9590.8290.8290.720.1390.9850.9990.9850.3290.3290.2230.9960.720.9590.4550.4550.3280.08330.9850.9850.5910.3290.9590.4550.8290.720.4550.7070.7060.7070.1150.7070.7070.7060.3371.00.7070.3380.7071.00.7070.7071.00.7070.7071.01.01.00.3361.01.01.00.3380.3380.1150.7070.7071.00.3381.00.7060.7060.7061.00.3380.1150.3380.3381.00.7070.707Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

Download the Displayed SVG for the ENCODE Panel