deTS Results for Cascot confidence score

Traits Information:

Trait ID:

4236

20121_raw
Cascot confidence score
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=20121
# cases = 0 | # controls = 10509
# SNPs = 13472743 | # genes = 21890
0.998
p (gene) < 0.05:  # TAGs = 1133
p (gene) < 0.01:  # TAGs = 249
p (gene) < 0.001:  # TAGs = 18
p (gene) < 1.0E-4:  # TAGs = 4
p (gene) < 1.0E-5: # TAGs = 1

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 0.9120.8790.8390.8390.9580.0420.05860.02040.1810.1410.2280.1070.009110.005920.02040.003770.009110.009110.9580.610.8390.7910.610.9580.9730.4730.2810.6750.4730.6750.9380.7360.2280.9990.8790.7910.6750.3410.6750.610.1390.1810.3410.4730.9120.8790.5410.5510.4070.8170.8170.8170.2790.1780.1050.1780.1780.6940.2790.1780.1780.1780.05780.05780.1050.4070.8170.1780.6940.4070.6940.5510.5510.5510.5510.6940.6940.2790.1050.6940.5510.9070.4070.8170.1050.9620.9980.05730.5510.05780.8170.6940.5510.817Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 0.580.0880.9880.6480.20.9030.6410.0880.1540.20.9030.004170.1950.9690.440.580.580.9320.7710.440.5090.5730.7120.930.9530.7710.440.8670.3720.580.980.3090.8670.9690.0880.5760.580.9990.120.3090.04710.001580.9030.9960.3670.2430.9540.790.3670.8910.9530.890.7890.6580.08630.1510.2420.6580.1510.790.2450.8910.9850.790.5110.3640.8910.9530.9530.2450.6580.8910.3670.6580.7880.1510.6580.5090.2430.9530.9540.9850.3670.2450.04590.1510.9850.954Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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