deTS Results for Mental health problems ever diagnosed by a professional: Anorexia nervosa

Traits Information:

Trait ID:

4458

20544_16_v2
Mental health problems ever diagnosed by a professional: Anorexia nervosa
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=20544
# cases = 690 | # controls = 117018
# SNPs = 8683619 | # genes = 21890
0.998
p (gene) < 0.05:  # TAGs = 1103
p (gene) < 0.01:  # TAGs = 201
p (gene) < 0.001:  # TAGs = 15
p (gene) < 1.0E-4:  # TAGs = 2
p (gene) < 1.0E-5: # TAGs = 0

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 0.8740.9090.7250.3870.5940.09640.03640.07110.03640.07110.01140.007440.1660.1280.05140.02520.3230.4550.9720.7250.9720.5940.3230.8320.9890.9090.9570.3870.8320.1280.8740.5250.5250.3870.8320.9820.6620.5250.2640.3870.7790.2640.7250.3230.9720.9360.09640.7490.7490.8730.8730.4260.09190.1680.04610.1680.280.04610.04610.1680.04610.04610.02130.280.09190.8730.9510.7490.8730.8730.8730.9510.9510.9870.280.280.4260.7490.7490.4260.7490.8730.5910.280.7490.5910.4260.1670.280.7490.280.7490.7490.168Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 0.9910.9420.7940.8430.1710.7380.2660.07170.002880.1320.7940.8840.8390.7940.9170.8430.9620.9850.9850.9430.9170.3260.6760.6050.05170.7380.5380.2180.7940.3320.1670.9990.8840.6050.3290.3290.6080.9750.01150.2180.0730.9170.8840.9620.7270.7260.7270.7270.07970.3980.8580.5620.07910.07970.7270.8590.9440.1490.9980.5640.8590.5640.9980.9850.9980.5610.1490.7260.5620.3980.2560.9440.7270.5640.9440.9440.7270.2550.7260.7260.2560.9440.01750.5640.1490.7270.9440.727Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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