deTS Results for Anaesthetics administered post delivery: General anaesthetic

Traits Information:

Trait ID:

4509

41220_1_v2
Anaesthetics administered post delivery: General anaesthetic
UK Biobank (UKBB)
Neale Lab, 2018
http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=41220
# cases = 363 | # controls = 1182
# SNPs = 7608897 | # genes = 21890
0.998
p (gene) < 0.05:  # TAGs = 1203
p (gene) < 0.01:  # TAGs = 274
p (gene) < 0.001:  # TAGs = 22
p (gene) < 1.0E-4:  # TAGs = 4
p (gene) < 1.0E-5: # TAGs = 2

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.3520.2930.7420.9140.9580.4160.2380.08660.2930.1150.5510.5510.4160.6820.1910.08660.7420.7420.04640.9720.6820.7420.8810.8810.5510.2930.3520.1910.9140.1490.3520.5510.4160.9820.5510.6820.7420.6820.01570.004460.6150.3520.9390.7420.9390.4160.8420.4640.4640.4640.6070.8510.1360.220.3310.07830.07830.220.3310.1360.4640.07830.04220.3310.3310.1360.8510.4640.8510.1360.9710.220.7410.9710.3310.9710.3310.07830.1360.9710.7410.6070.6070.9270.9270.1360.07830.740.07830.6070.4640.8510.220.8511.01.00.04280.04280.1891.01.01.01.01.01.01.01.01.01.01.01.01.00.04280.04280.560.04281.00.1890.561.00.560.560.560.1891.00.1890.560.04281.00.1891.00.561.00.560.5590.561.00.560.1891.01.0Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.5370.8340.6050.6710.9370.8770.9350.05570.3970.07780.2770.9960.9350.4680.6050.6050.2770.4680.4680.05680.2240.1330.9720.7290.4640.9110.7320.8360.1040.3360.9080.40.4680.3330.2210.003470.005640.4680.3360.9820.4680.40.40.7320.8280.8270.4250.9140.9890.9140.9890.4230.5670.5690.8280.9140.8260.03310.9140.190.9140.5690.9140.7090.7090.4210.9140.7080.2930.9650.4250.7090.2950.5690.4210.1140.8280.5670.0630.5670.4250.190.4250.5690.5690.7090.2950.4251.01.00.170.5361.01.01.00.5351.01.01.00.5360.1690.5360.5361.00.5361.00.170.5360.5360.5351.01.00.171.01.00.5360.5361.01.01.00.5360.5350.5351.01.01.01.00.170.5361.00.005370.536Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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