deTS Results for Palmar fascial fibromatosis [Dupuytren]

Traits Information:

Trait ID:

664

M13_DUPUTRYEN
Palmar fascial fibromatosis [Dupuytren]
UK Biobank (UKBB)
Neale Lab, 2018
N/A
# cases = 2948 | # controls = 358246
# SNPs = 11118623 | # genes = 21888
1.067
p (gene) < 0.05:  # TAGs = 2153
p (gene) < 0.01:  # TAGs = 769
p (gene) < 0.001:  # TAGs = 205
p (gene) < 1.0E-4:  # TAGs = 95
p (gene) < 1.0E-5:  # TAGs = 57

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 p < 1.0E-4 p < 1.0E-5 0.01730.06710.004680.01730.01270.990.980.9720.9720.9610.9860.980.9480.5620.9720.9860.8890.9720.1060.05240.5110.06710.5110.1310.1920.8610.6130.1310.6130.7930.2280.6130.5620.1310.6130.2690.6620.5620.5110.2690.790.08490.9480.9120.01730.1310.08490.4070.3280.04830.1030.04830.8620.8620.9410.7380.5770.9410.9640.8060.7380.9070.9640.9890.9890.4070.001380.7380.00750.3280.002490.1950.8620.8060.1950.8060.6610.5770.8060.8620.3280.3280.1440.7380.5770.5770.4910.940.4910.4070.4910.00750.2570.1030.3170.630.0280.1970.01240.8920.8920.960.630.4670.8920.8920.7790.7790.960.990.1970.7790.8920.1120.7790.1970.4670.1970.7790.8920.8920.1970.8920.960.4670.7790.7790.1120.8920.7790.990.960.3170.1970.6280.1970.630.960.0280.1970.05820.2240.410.004810.1050.001350.9650.8430.8430.8430.6370.8430.8430.8430.8430.8430.9650.2240.8430.6370.004810.410.04290.2240.1050.8430.8430.8430.1050.9650.9650.410.8430.9650.004810.6370.8430.9650.9650.1050.1050.4090.1050.2240.8430.004810.04290.6370.2950.5730.03950.03950.01071.01.01.00.8580.5731.01.00.8581.01.01.00.8581.00.8580.03950.5730.2950.8580.2950.8580.8580.8580.120.8581.00.5731.00.8580.01071.00.8580.8580.8580.2950.2950.2950.03950.03950.8580.120.2950.573Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 p < 1.0E-4 p < 1.0E-5 0.1720.05510.05660.9780.7370.3830.6820.9780.9040.9270.5910.2880.02350.8170.1720.3340.3340.6910.9060.6910.7370.004570.4340.9040.2410.09160.6914.66E-40.4340.1720.1990.04360.1720.9430.4810.9260.7790.03320.3340.9970.7790.9060.03320.5390.6930.2770.1140.9970.7680.7680.7630.9720.9720.610.610.1140.01350.9930.0140.2140.03540.5240.9240.9970.5240.00470.280.2770.2770.2140.3550.1140.8320.5240.03430.2140.2140.9520.6080.690.6930.280.5240.8320.1590.7680.5240.4380.7590.4380.1770.9540.9540.4390.8780.9540.8790.6040.6040.2920.2890.9540.09790.4390.2920.6040.9880.8790.6040.09650.8790.6020.9880.02320.02320.1770.4390.4390.1750.1770.7590.8790.9980.6020.4390.6040.1770.9540.9540.6040.4390.7590.6140.3840.03651.00.8290.09280.3830.960.3840.6140.6140.3850.09180.8290.09280.3850.2040.8290.960.960.960.3830.6141.00.960.01250.09280.3850.8290.3850.01230.2040.960.6131.00.3840.3850.6140.3850.6140.8290.3850.6140.8290.5420.2650.1021.00.8420.2660.541.00.8411.00.8420.8420.1020.5420.1021.00.1020.8421.00.8420.8420.2650.5421.01.00.1020.1020.2660.8420.2660.03140.8421.00.5411.00.5410.5421.00.2660.2660.8420.2660.5420.842Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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