deTS Results for Retinal breaks without detachment

Traits Information:

Trait ID:

938

H7_RETINALBREAK
Retinal breaks without detachment
UK Biobank (UKBB)
Neale Lab, 2018
N/A
# cases = 818 | # controls = 360376
# SNPs = 8964886 | # genes = 21890
1.017
p (gene) < 0.05:  # TAGs = 1274
p (gene) < 0.01:  # TAGs = 290
p (gene) < 0.001:  # TAGs = 36
p (gene) < 1.0E-4:  # TAGs = 11
p (gene) < 1.0E-5: # TAGs = 2

Manhattan Plot of All SNPs in the GWAS



Manhattan Plot of All Genes in the GWAS

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deTS Enrichment Analysis Using the GTEx Panel

p < 0.05 p < 0.01 p < 0.001 0.1760.4510.08040.3270.3870.7070.3270.7620.6460.3870.3870.3870.6460.4510.5170.7620.3870.1760.3870.08040.1760.1760.9830.220.6460.4510.7070.5820.8910.7070.5820.7070.5820.4510.5820.9610.2710.1060.8120.5820.2180.2710.8550.7620.05960.3270.5820.6830.4120.8920.8920.8020.190.1170.190.6830.5480.1170.1170.5480.190.190.4120.5480.290.5480.1170.290.6830.8920.4120.290.6830.8920.5480.8920.290.5480.4120.5480.9810.9810.6830.5480.6830.9950.8920.1890.290.950.8020.290.8920.5481.01.00.2830.2830.2830.2830.01880.01880.08470.08470.01880.01880.2830.2830.08470.01880.2830.2831.00.661.01.01.01.00.660.660.660.660.660.660.661.00.661.01.00.660.661.01.01.00.08441.01.00.661.01.00.283Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel

p < 0.05 p < 0.01 p < 0.001 0.7890.6720.4120.8360.2360.4120.6040.02270.7860.3490.970.4780.5380.7890.6120.9090.7890.5450.9090.8760.8760.7290.6750.7860.9340.8360.8760.7890.5450.4780.7290.6750.6120.980.5420.1870.290.2360.1150.7350.7350.290.1490.4120.9440.7840.6610.9790.2680.3880.1710.3860.660.6610.9790.6610.7820.6610.6610.7850.9940.7850.9790.7850.1730.6580.6610.3860.7840.6610.1730.9790.7850.9440.9780.5240.5240.2670.3860.2670.5240.3880.2680.5240.6610.1730.5240.7851.01.00.08411.00.6580.08411.00.6580.6580.2821.00.6580.6571.00.2820.2821.00.6580.6580.6580.2820.6570.6581.01.00.6580.2820.6580.6580.6580.6570.6580.6580.01850.6581.01.01.01.00.6580.2820.2821.01.0Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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