Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

10277

Name

UBE4B

Synonym

E4|HDNB1|UBOX3|UFD2|UFD2A;ubiquitination factor E4B;UBE4B;ubiquitination factor E4B

Definition

UFD2A-III/UBE4B-III splice isoform|homologous to yeast UFD2|homozygously deleted in neuroblastoma 1|homozygously deleted in neuroblastoma-1|ubiquitin conjugation factor E4 B|ubiquitin fusion degradation protein 2|ubiquitin-fusion degradation protein 2|ubi

Position

1p36.3

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

17405

TUSON P-value

1

Pathways and Diseases

Pathway

Protein processing in endoplasmic reticulum;KEGG PATHWAY;hsa04141

Pathway

Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120

External Links

Links to Entrez Gene

10277

Links to all GeneRIF Items

10277

Links to iHOP

10277

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>10277 : length: 3909
atggaggagctgagcgctgatgagattcgacggaggcgccttgcacgacttgctggtgga
cagacctctcagccaaccaccccactcacctctccccagagggagaaccctccggggcct
cccatagcggcatcagccccaggaccctctcagagtcttggtctcaatgtccacaacatg
accccagctacctccccaataggtgcatcaggagtagcccatcgaagccagagcagtgaa
ggagtcagttctctcagcagctcgccctctaatagccttgaaacgcaatctcagtctctc
tcacgttcccagagcatggatatcgatggtgtctcatgtgagaaaagcatgtcccaggtg
gatgtggattcaggaattgaaaacatggaggttgatgaaaatgatcgaagagaaaagcgg
agcctcagtgataaggagccttcctcgggccctgaagtgtctgaagagcaggccttacag
ctggtctgtaagatcttccgtgtctcttggaaggaccgggacagagatgtcatctttctt
tcttctctttctgcacagtttaagcagaacccaaaagaagtattctccgattttaaggac
ttgattggccagattttaatggaagtgctaatgatgtccactcagaccagagatgaaaac
ccatttgccagtctgacagccacatcacagccaattgctgcagcagcacggtcaccagac
agaaatctcttgctaaacactggctccaatccaggaacaagccccatgttctgcagcgtg
gcttcctttggtgccagctctttgtctagcctctatgaaagtagtccggctcccactccc
agtttctggagctctgttcccgtgatgggcccgtctcttgcctcaccttcccgtgcagcc
agccagttggctgtgccttccactcccctcagtcctcacagtgcagcctctggaactgct
gcgggaagccagccttcatccccgcggtatcgcccctacactgtcactcacccatgggcg
tcctcaggcgtctccattctgtcgagctccccaagtccccctgccctcgccagtagcccc
caagcagtgcccgccagcagttccagacagaggcccagcagcacgggtccacccctacca
cccgcctcacccagtgccacgagcagacgcccctcctccctgaggatctctcctagtttg
ggagcctctggtggagcaagtaattgggattcctacagtgaccatttcaccattgaaacc
tgcaaagagacagatatgctgaactacctcatcgagtgtttcgaccgagttggaatagag
gaaaaaaaagcaccaaagatgtgcagccagccagcagtcagccagcttctgagcaacatc
cgctcacagtgcatatcccatactgctttagtactacaaggctccctaacacagcccagg
tccttgcagcagccgtccttcctagtgccgtatatgctgtgtaggaatctcccatatggc
ttcattcaggaactggtgagaaccactcaccaggatgaagaagtgttcaagcagatattt
atccccattttacaaggcctggctcttgctgccaaagagtgctccctcgacagtgactac
tttaaataccccctcatggcactaggtgagctctgtgaaaccaagtttgggaagacacac
cctgtgtgcaatttggttgcttctttgcggttgtggttgccgaaatccttaagtcctggc
tgtgggcgggagctgcagagactctcttacttaggggctttctttagcttctcagtcttt
gcagaagatgatgttaaagtggttgaaaaatacttctcagggcctgccattaccctggaa
aacactcgtgtggttagccaatcattgcagcattacttagagctcggaaggcaagagctt
tttaagattctgcatagtattttgttaaatggcgaaacccgtgaggctgctctcagttac
atggcggctgtcgtcaatgccaatatgaagaaagcacagatgcagacagatgatagattg
gtgtctacagatggatttatgctgaatttcctttgggtactgcagcagctaagtacaaaa
atcaagttagaaacagttgatcccacgtatatttttcacccaagatgtcggattactctt
cccaatgatgagacgcgtgtgaatgcaacgatggaagatgtgaatgactggctgactgaa
ctctatggcgatcagcctccattttctgagccgaaattccctacggagtgcttctttctc
accctgcatgctcaccacctctctattctgcctagttgccgtcgctatatccgcagactc
cgggctatccgggagctcaatagaactgtagaagatttgaaaaataatgaaagccaatgg
aaagattccccactggcaactagacaccgcgaaatgctgaagcgctgtaaaactcagctt
aagaaactggtacggtgcaaggcctgtgctgatgctggcctacttgacgagagcttcctg
agaagatgtctgaatttttatggccttctcattcagctgctgctccgcatcctggacccc
gcatatcccgatataacactgcctttaaattcagatgtccccaaggtatttgcagcgttg
cctgagttttatgtagaagatgttgcagaatttttattttttattgtacaatactctccc
caggcgctttatgagccctgtactcaggatattgtgatgttccttgttgtgatgttgtgc
aaccagaactacatccgaaacccatatttggtggccaaactggtagaagtcatgtttatg
accaaccctgctgttcagccacgaacccagaagttttttgaaatgattgagaaccatcct
ctctccaccaagttgttggtaccttccctgatgaagttttatacagatgttgagcatacc
ggagccaccagtgagttttatgacaagttcacaattcgctatcatattagcaccattttt
aaaagcctttggcaaaacatagctcaccatggcacctttatggaggagttcaactccggg
aagcagtttgttcgctatataaacatgttgataaacgacacgacgtttttgctcgatgaa
agtctggagtctctgaagcgaatccatgaagtgcaggaagagatgaagaacaaagaacag
tgggaccagttgccccgggatcagcagcaggctcgtcagtctcagcttgctcaggatgag
cgtgtgtcccgctcttacctcgccctggccaccgaaaccgtggacatgttccacatcctc
acgaagcaggtccagaagcccttcctcagaccggagcttggaccccgattggctgcaatg
ctgaactttaatcttcagcaactttgtggccccaagtgccgtgacctgaaagttgaaaac
cctgagaaatacggctttgaaccaaagaagctgttggaccaactgacggatatttactta
cagctggactgtgctcggttcgcgaaagccattgctgacgaccagagatcctacagtaag
gaattgtttgaagaagttatttcaaagatgcggaaggcagggatcaaatccacaatagca
atagaaaaatttaagctgctcgccgagaaagtggaggagatagtggccaagaacgcacgc
gcagaaatcgactacagcgacgctcctgatgagttcagagaccctctgatggacaccctc
atgacagaccccgtgcggctgccctctggcaccatcatggaccgctccatcatcctgcgg
cacctgctcaactcccccacggaccccttcaaccggcagacgctgacagagagcatgctg
gaaccagtgccagaactgaaagagcagattcaggcgtggatgagagagaaacagaacagc
gatcactaa

Protein Sequence

>10277 : length: 1302
MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM
TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV
DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL
SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD
RNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAA
SQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSP
QAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYSDHFTIET
CKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPR
SLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLDSDY
FKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAFFSFSVF
AEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETREAALSY
MAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHPRCRITL
PNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRL
RAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFL
RRCLNFYGLLIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFFIVQYSP
QALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENHP
LSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFMEEFNSG
KQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDE
RVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVEN
PEKYGFEPKKLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAGIKSTIA
IEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILR
HLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH



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