| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 10320 |
Name | IKZF1 |
Synonym | Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1;IKAROS family zinc finger 1 (Ikaros);IKZF1;IKAROS family zinc finger 1 (Ikaros) |
Definition | CLL-associated antigen KW-6|DNA-binding protein Ikaros|ikaros family zinc finger protein 1|lymphoid transcription factor LyF-1|protein phosphatase 1, regulatory subunit 92|zinc finger protein, subfamily 1A, 1 (Ikaros) |
Position | 7p12.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 8834 |
TUSON P-value | 1 |
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Pathways and Diseases |
|
Pathway | Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039 |
Disease | Leukemia, acute lymphoblastic;OMIM |
Disease | hippocampal atrophy;GAD |
Disease | Bone marrow disease;FunDO |
Disease | Hippocampal atrophy;NHGRI |
Disease | Mean corpuscular volume;NHGRI |
Disease | HEMATOLOGICAL;GAD |
Disease | Acute lymphoblastic leukemia (childhood);NHGRI |
Disease | Acute lymphoblastic leukemia (childhood);GAD |
Disease | IMMUNE;GAD |
Disease | Lymphoma;FunDO |
Disease | Leukemia;FunDO |
Disease | CANCER;GAD |
Disease | Lymphoproliferative disorder;FunDO |
Disease | Systemic lupus erythematosus;NHGRI |
Disease | Hematopoietic system disease;FunDO |
Disease | systemic lupus erythematosus;GAD |
Disease | mean corpuscular volume;GAD |
Disease | NEUROLOGICAL;GAD |
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External Links |
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Links to Entrez Gene | 10320 |
Links to all GeneRIF Items | 10320 |
Links to iHOP | 10320 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>10320 : length: 1560 atggatgctgatgagggtcaagacatgtcccaagtttcagggaaggaaagcccccctgta agcgatactccagatgagggcgatgagcccatgccgatccccgaggacctctccaccacc tcgggaggacagcaaagctccaagagtgacagagtcgtggccagtaatgttaaagtagag actcagagtgatgaagagaatgggcgtgcctgtgaaatgaatggggaagaatgtgcggag gatttacgaatgcttgatgcctcgggagagaaaatgaatggctcccacagggaccaaggc agctcggctttgtcgggagttggaggcattcgacttcctaacggaaaactaaagtgtgat atctgtgggatcatttgcatcgggcccaatgtgctcatggttcacaaaagaagccacact ggagaacggcccttccagtgcaatcagtgcggggcctcattcacccagaagggcaacctg ctccggcacatcaagctgcattccggggagaagcccttcaaatgccacctctgcaactac gcctgccgccggagggacgccctcactggccacctgaggacgcactccgttggtaaacct cacaaatgtggatattgtggccgaagctataaacagcgaagctctttagaggaacataaa gagcgctgccacaactacttggaaagcatgggccttccgggcacactgtacccagtcatt aaagaagaaactaatcacagtgaaatggcagaagacctgtgcaagataggatcagagaga tctctcgtgctggacagactagcaagtaacgtcgccaaacgtaagagctctatgcctcag aaatttcttggggacaagggcctgtccgacacgccctacgacagcagcgccagctacgag aaggagaacgaaatgatgaagtcccacgtgatggaccaagccatcaacaacgccatcaac tacctgggggccgagtccctgcgcccgctggtgcagacgcccccgggcggttccgaggtg gtcccggtcatcagcccgatgtaccagctgcacaagccgctcgcggagggcaccccgcgc tccaaccactcggcccaggacagcgccgtggagaacctgctgctgctctccaaggccaag ttggtgccctcggagcgcgaggcgtccccgagcaacagctgccaagactccacggacacc gagagcaacaacgaggagcagcgcagcggtctcatctacctgaccaaccacatcgccccg cacgcgcgcaacgggctgtcgctcaaggaggagcaccgcgcctacgacctgctgcgcgcc gcctccgagaactcgcaggacgcgctccgcgtggtcagcaccagcggggagcagatgaag gtgtacaagtgcgaacactgccgggtgctcttcctggatcacgtcatgtacaccatccac atgggctgccacggcttccgtgatccttttgagtgcaacatgtgcggctaccacagccag gaccggtacgagttctcgtcgcacataacgcgaggggagcaccgcttccacatgagctaa |
Protein Sequence |
>10320 : length: 519 MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQQSSKSDRVVASNVKVE TQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCD ICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNY ACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTLYPVI KEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYE KENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEGTPR SNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLTNHIAP HARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIH MGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHMS |