Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

10335

Name

MRVI1

Synonym

IRAG|JAW1L;murine retrovirus integration site 1 homolog;MRVI1;murine retrovirus integration site 1 homolog

Definition

IP3R-associated cGMP kinase substrate|JAW1-related protein MRVI1|inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate|inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate|protein MRVI1

Position

11p15

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

10840

TUSON P-value

1

Pathways and Diseases

Pathway

Vascular smooth muscle contraction;KEGG PATHWAY;hsa04270

Pathway

Hemostasis;Reactome;REACT:604

Disease

Platelet aggregation;NHGRI

External Links

Links to Entrez Gene

10335

Links to all GeneRIF Items

10335

Links to iHOP

10335

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>10335 : length: 2712
atgggaatggatttgacttgtccttttggcgtctccccagcctgtggagcccaggcctct
tggagcatctttggggctgacgcagcggaggttccgggcacacgtggccactcccagcag
gaggctgccatgccccacattcccgaggacgaggagccccccggagagccacaggcagcc
cagagccctgccggccaaggtcctcctaccgcaggagtatcttgcagtccaactcccacg
attgtcctgactggggatgccacttcaccagaaggagaaaccgacaaaaacctggccaac
agagttcacagtccccacaagaggctttctcaccgacacttgaaggtgtccactgcctcc
ctgacatctgtggaccccgcggggcacatcattgacctggtgaatgaccagctgccagac
atcagcatctcagaggaggacaagaagaaaaacctggcgctgctggaagaagccaagttg
gtgagtgagcgattcctgacccgccgtgggaggaagtccaggagcagccccggagactcc
ccatcagctgtttccccgaacctcagccccagcgcttctcctacatcctctcggagcaac
tcacttacagtccccaccccgccaggtttggatgtgtgcagtggcccgccatcccctctg
cctggagcaccaccacagaagggggatgaggccgacgtctcttcacctcaccctggcgag
cctaacgtccccaaagggctagctgacaggaagcagaatgaccagaggaaagtgtctcag
ggcaggctggctcctcgtcctcctccagttgagaagtccaaagagattgcaatagaacaa
aaggaaaacttcgatcccctccagtaccccgagaccacacccaaaggcctagctcctgtt
acaaacagcagtgggaaaatggccctgaacagccctcagcctggccccgtggagagcgag
ctggggaagcagctcttgaaaacgggctgggagggcagccctctgccgagaagtccaacc
caggatgcggcaggagtgggtcccccagcctcccaggggagaggcccagctggagagccg
atggggcccgaggctggctccaaagctgagcttccacccactgtgtcccggcccccgctg
ctgcgagggctctcctgggacagtggccctgaagaacctggcccccggctgcagaaagtg
cttgccaagctgccactggcagaggaagaaaagcgttttgcaggcaaggccggcggcaag
ctggccaaggcccctggtctcaaagactttcagatacaagtgcagcccgtgcggatgcag
aaactgaccaagctccgagaggagcacatcctgatgagaaatcagaacttagtggggctc
aagcttccagaccttagtgaagcagctgagcaggaaaaagggcttccttctgaactctcc
ccagctattgaggaagaagagtcaaagagtggcttagatgtcatgcctaatatttctgat
gtgctgctgcgcaaactgcgggtccacaggagtctccctggaagtgcccctccactcact
gaaaaggaagttgagaacgtgtttgtgcaactgtccttggcctttagaaatgacagctac
actctggaatctagaattaaccaggctgaaagggaacgcaacctgacagaggagaacact
gagaaagaactggaaaacttcaaagcttccattacgtcctcagcttcactctggcaccac
tgtgagcaccgggaaacctaccagaagttgctggaggacatcgctgtcctgcaccgcctg
gctgcccgcctctccagccgagctgaggtggtaggcgccgtccgccaggaaaagcgcatg
tcgaaagcaacggaagtgatgatgcagtatgtggagaatctaaagaggacgtatgagaag
gaccatgcggagctcatggagtttaaaaagcttgcaaatcagaattcaagccgcagctgt
ggcccctctgaagatggggtccctcgcacggcacggtccatgtccctcacgctgggaaag
aatatgcctcgccggagggtcagcgttgctgtggttcctaagtttaatgccctgaatctg
cctggccaaactcccagctcatcatccattccctccttaccagccttgtcggaatcaccc
aatgggaaaggcagcctacctgtcacttcagcactgcctgcacttttggaaaatggaaag
acaaatggggacccagattgtgaagcctctgctcctgcgctgaccctgagctgcctggag
gagcttagtcaggagaccaaggccaggatggaggaagaagcctacagcaagggattccaa
gaaggtctaaagaagaccaaagaacttcaagacctgaaggaggaggaggaagaacagaag
agtgagagtcctgaggaacctgaagaggtagaagaaactgaggaagaggaaaagggccca
agaagcagcaaacttgaagaattggtccatttcttacaagtcatgtatcccaaactgtgt
cagcactggcaagtgatctggatgatggctgcagtgatgctggtcttgactgttgtgctg
gggctctacaattcctataactcttgtgcagagcaggctgatgggccccttggaagatcc
acttgctcggcagcccagagggactcctggtggagctcaggactccagcatgagcagcct
acagagcagtag

Protein Sequence

>10335 : length: 903
MGMDLTCPFGVSPACGAQASWSIFGADAAEVPGTRGHSQQEAAMPHIPEDEEPPGEPQAA
QSPAGQGPPTAGVSCSPTPTIVLTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTAS
LTSVDPAGHIIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDS
PSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGE
PNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPV
TNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEP
MGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGK
LAKAPGLKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELS
PAIEEEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSY
TLESRINQAERERNLTEENTEKELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRL
AARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSC
GPSEDGVPRTARSMSLTLGKNMPRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESP
NGKGSLPVTSALPALLENGKTNGDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQ
EGLKKTKELQDLKEEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLC
QHWQVIWMMAAVMLVLTVVLGLYNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQP
TEQ



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