| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 10788 |
Name | IQGAP2 |
Synonym | -;IQ motif containing GTPase activating protein 2;IQGAP2;IQ motif containing GTPase activating protein 2 |
Definition | ras GTPase-activating-like protein IQGAP2 |
Position | 5q13.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 9014 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Disease | Hearing impairment;NHGRI |
Disease | Stomach cancer;FunDO |
Disease | hearing impairment;GAD |
Disease | smoking cessation;GAD |
Disease | CHEMDEPENDENCY;GAD |
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External Links |
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Links to Entrez Gene | 10788 |
Links to all GeneRIF Items | 10788 |
Links to iHOP | 10788 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>10788 : length: 4728 atgccacacgaagagctgccgtcgctgcagagaccccgctatggctctattgtggacgat gaaaggctctctgcagaggagatggatgagaggaggcggcagaacattgcttatgaatat ctgtgccacttagaggaagccaaaaggtggatggaagtttgcttagttgaagaattgcca ccaaccactgaattggaagaagggctccggaatggagtttaccttgcaaagttagccaag ttctttgccccgaaaatggtatcagagaaaaagatctatgatgtggaacaaacacgttat aagaagtctggccttcattttcgacacacagataataccgtccagtggttaagagcgatg gagtctattggtctacccaagatattttatccagaaacaacagatgtctatgatcggaaa aacataccaagaatgatatattgcattcacgcactgagtttgtatctgttcaaactagga atagcaccccagatccaggatttgttgggcaaagtagacttcacagaggaggaaatcagt aatatgagaaaagaacttgagaaatatggaatacagatgccatctttcagcaaaataggt ggtattctggccaatgaactgtccgtggatgaagctgcattacatgctgcagttatagcc attaatgaagcagttgaaaaaggaatagcagagcaaaccgttgtaacactaagaaaccca aatgcggttttaactttagtggatgacaaccttgcaccagaatatcagaaagaactctgg gatgccaaaaagaaaaaagaggaaaatgcaagactgaagaatagctgtatttcagaagaa gaaagagatgcttatgaagaactgctgacacaagcagaaatccaaggcaatattaataaa gtcaacaggcaggctgcagtggaccatatcaatgctgtcattccggaaggtgaccccgag aatacgctgcttgcactgaagaaaccagaggcccagctgcctgctgtttatccctttgct gctgccatgtatcagaacgaacttttcaacctccagaaacagaacaccatgaactacttg gcccacgaggagcttttgattgctgtggaaatgttgtctgctgttgctttactaaaccag gccttggaaagcaacgatcttgtgtctgtgcagaatcaactcagaagccccgcaataggc ttaaacaatctggacaaggcatatgtggaacgttatgcaaacacactactctctgttaaa ctagaagttttatcccaagggcaagataacttaagctggaatgaaattcagaattgtatt gatatggttaatgctcaaattcaagaagaaaatgaccgagttgtagctgtagggtacatc aatgaagctattgatgaagggaatcctttgaggactttagaaactttgctcctacctact gcgaatattagtgatgtggacccagcccatgcccagcactaccaggatgttttataccat gctaaatcacagaaactcggagactctgagagtgtttccaaagtgctttggctggatgag atacagcaagccgtcgatgatgccaacgtggacgaggacagagcaaaacaatgggttact ctggtggttgatgttaatcagtgtttggaaggaaaaaaatcaagtgatattttgtctgta ttgaagtcttccacttctaatgcaaatgacataatcccggagtgtgctgacaaatactat gatgcccttgtgaaggcaaaagagctcaaatctgaaagagtgtctagtgacggttcatgg ctcaaactcaacctgcacaaaaaatatgactactattacaacactgattcaaaagagagt tcctgggtcacacctgaatcatgcttgtataaagaatcatggctcacaggaaaagaaatc gaggacattattgaggaagtcacagtaggttacattcgtgagaatatatggtctgcttca gaagagttgcttcttcgctttcaagccacaagctcaggacccatccttagggaagagttt gaagctagaaaatcatttttgcatgaacaagaagagaatgtggtcaaaatacaggctttt tggaaaggatataaacaacggaaggagtatatgcacaggcggcaaacgttcattgataat actgattctattgtgaagattcagtcctggttccgaatggcaactgcaagaaagagctat ctttcaagactacagtatttcagagatcataataatgaaattgtgaaaatacagtcactg ttgagagcgaacaaagctagagatgactacaaaacattggttggctctgaaaacccacca ttaacagtaattcgcaaatttgtatacctgctggaccaaagtgatttggatttccaggag gaactagaggttgcacgattaagggaagaagtagtgaccaagatcagggccaatcaacag ctggaaaaagacctgaacctgatggacatcaagattggactgctggtgaagaacaggatc acactagaggatgtaatttcacacagtaaaaagctgaacaagaaaaaaggaggagaaatg gaaatactgaataacaccgacaaccaaggaataaaaagtttgagtaaggagaggagaaaa acactagaaacatatcagcagctgttttaccttttacagaccaaccctttatacttggct aagctgattttccagatgccacagaacaagtccactaaatttatggatactgttattttc acactatataattatgcctctaatcagcgagaagaatatctacttctcaagctttttaaa actgctctggaggaagaaataaaatcaaaagtggaccaggtacaggacatagttactggt aaccctacagtcatcaagatggtcgtcagcttcaatagaggtgcccggggacagaacacc ctgcgccaactcctggctccagtggtaaaagagatcatcgacgacaagtcgctgattatc aacacaaaccctgtagaggtgtacaaggcttgggtgaaccaactagaaacacagactgga gaggccagcaagttgccttatgatgtgaccacagaacaagctctaacatacccagaagtg aaaaataaactggaggcttccattgagaacctgagaagggtcaccgacaaagtcctgaat tctatcatttcttcccttgatctactgccttatggattgaggtatatagccaaagtactg aagaattcgatccatgagaaattccccgatgcaacagaagatgagctattaaagattgtt ggaaacctcctgtactatcggtacatgaatccagccattgtagctccagatggctttgat atcatcgacatgacagctggaggtcagataaattctgaccaaaggagaaacttaggatca gtggccaaggttcttcagcacgcagcctccaacaagctgtttgaaggagaaaatgagcat ctctcatctatgaacaattatttatcagagacgtatcaggaattcaggaaatatttcaaa gaagcatgtaatgtccctgagccagaagagaagtttaatatggacaaatacacagacctg gtgacagtcagcaaaccagtcatttatatttcaattgaagaaatcatcagcacacactca ctcctgttggaacaccaggatgcaattgcccctgagaaaaatgacttactgagtgaattg ctggggtcgctgggagaggtgccaaccgtggaatcttttcttggggaaggagcagttgac cccaatgaccctaacaaggcaaatacactaagtcagctttcaaagaccgagatttctctt gtcttgacaagcaaatatgacatagaggacggtgaagctatagatagccgaagcctcatg ataaagaccaagaagctgataattgatgtgatccggaaccagccagggaacacattgaca gaaatcttagagacaccagcaactgcgcaacaggaggtagaccatgccacggacatggtg agccgtgcaatgatagattccaggactccagaagaaatgaagcatagccaatctatgatt gaagatgcacagctgcctcttgagcagaagaagaggaaaatccagaggaatcttcggacg ttggaacagactggacacgtgtcatccgaaaataaataccaagacattctcaatgagatt gccaaggatattcgaaatcaaagaatctatcgtaagcttcgaaaagctgaattggcaaaa cttcagcagaccctgaatgcacttaacaagaaggcagcattttatgaagagcaaatcaat tattatgacacctacataaagacttgtttagacaacttaaaaagaaaaaatactcggaga tcaattaaactagatggaaaaggagaacccaaaggggcgaagagagcgaagccagtgaag tacactgcagcaaagctgcatgagaaaggtgtcctgctagatatagatgatcttcaaaca aaccagtttaagaatgttacatttgatatcatagctactgaagatgtaggcattttcgat gtaagatcaaaattccttggtgttgagatggaaaaggtgcaactcaatattcaggattta cttcagatgcaatatgaaggagtagctgtaatgaaaatgtttgataaggttaaagtgaat gtaaaccttctcatatacctgctgaacaagaagttctatggaaagtga |
Protein Sequence |
>10788 : length: 1575 MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVEELP PTTELEEGLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKKSGLHFRHTDNTVQWLRAM ESIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEIS NMRKELEKYGIQMPSFSKIGGILANELSVDEAALHAAVIAINEAVEKGIAEQTVVTLRNP NAVLTLVDDNLAPEYQKELWDAKKKKEENARLKNSCISEEERDAYEELLTQAEIQGNINK VNRQAAVDHINAVIPEGDPENTLLALKKPEAQLPAVYPFAAAMYQNELFNLQKQNTMNYL AHEELLIAVEMLSAVALLNQALESNDLVSVQNQLRSPAIGLNNLDKAYVERYANTLLSVK LEVLSQGQDNLSWNEIQNCIDMVNAQIQEENDRVVAVGYINEAIDEGNPLRTLETLLLPT ANISDVDPAHAQHYQDVLYHAKSQKLGDSESVSKVLWLDEIQQAVDDANVDEDRAKQWVT LVVDVNQCLEGKKSSDILSVLKSSTSNANDIIPECADKYYDALVKAKELKSERVSSDGSW LKLNLHKKYDYYYNTDSKESSWVTPESCLYKESWLTGKEIEDIIEEVTVGYIRENIWSAS EELLLRFQATSSGPILREEFEARKSFLHEQEENVVKIQAFWKGYKQRKEYMHRRQTFIDN TDSIVKIQSWFRMATARKSYLSRLQYFRDHNNEIVKIQSLLRANKARDDYKTLVGSENPP LTVIRKFVYLLDQSDLDFQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRI TLEDVISHSKKLNKKKGGEMEILNNTDNQGIKSLSKERRKTLETYQQLFYLLQTNPLYLA KLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTG NPTVIKMVVSFNRGARGQNTLRQLLAPVVKEIIDDKSLIINTNPVEVYKAWVNQLETQTG EASKLPYDVTTEQALTYPEVKNKLEASIENLRRVTDKVLNSIISSLDLLPYGLRYIAKVL KNSIHEKFPDATEDELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSDQRRNLGS VAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFKEACNVPEPEEKFNMDKYTDL VTVSKPVIYISIEEIISTHSLLLEHQDAIAPEKNDLLSELLGSLGEVPTVESFLGEGAVD PNDPNKANTLSQLSKTEISLVLTSKYDIEDGEAIDSRSLMIKTKKLIIDVIRNQPGNTLT EILETPATAQQEVDHATDMVSRAMIDSRTPEEMKHSQSMIEDAQLPLEQKKRKIQRNLRT LEQTGHVSSENKYQDILNEIAKDIRNQRIYRKLRKAELAKLQQTLNALNKKAAFYEEQIN YYDTYIKTCLDNLKRKNTRRSIKLDGKGEPKGAKRAKPVKYTAAKLHEKGVLLDIDDLQT NQFKNVTFDIIATEDVGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVMKMFDKVKVN VNLLIYLLNKKFYGK |