| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 112399 |
Name | EGLN3 |
Synonym | HIFP4H3|HIFPH3|PHD3;egl-9 family hypoxia-inducible factor 3;EGLN3;egl-9 family hypoxia-inducible factor 3 |
Definition | HIF prolyl hydroxylase 3|HIF-PH3|HIF-prolyl hydroxylase 3|HPH-1|HPH-3|egl nine homolog 3|egl nine-like protein 3 isoform|hypoxia-inducible factor prolyl hydroxylase 3|prolyl hydroxylase domain-containing protein 3 |
Position | 14q13.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 6375 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Hypoxia response via HIF activation;PANTHER;P00030 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Renal cell carcinoma;KEGG PATHWAY;hsa05211 |
Pathway | HIF-1-alpha transcription factor network;PID Curated;200172 |
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External Links |
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Links to Entrez Gene | 112399 |
Links to all GeneRIF Items | 112399 |
Links to iHOP | 112399 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>112399 : length: 720 atgcccctgggacacatcatgaggctggacctggagaaaattgccctggagtacatcgtg ccctgtctgcacgaggtgggcttctgctacctggacaacttcctgggcgaggtggtgggc gactgcgtcctggagcgcgtcaagcagctgcactgcaccggggccctgcgggacggccag ctggcggggccgcgcgccggcgtctccaagcgacacctgcggggcgaccagatcacgtgg atcgggggcaacgaggagggctgcgaggccatcagcttcctcctgtccctcatcgacagg ctggtcctctactgcgggagccggctgggcaaatactacgtcaaggagaggtctaaggca atggtggcttgctatccgggaaatggaacaggttatgttcgccacgtggacaaccccaac ggtgatggtcgctgcatcacctgcatctactatctgaacaagaattgggatgccaagcta catggtgggatcctgcggatatttccagaggggaaatcattcatagcagatgtggagccc atttttgacagactcctgttcttctggtcagatcgtaggaacccacacgaagtgcagccc tcttacgcaaccagatatgctatgactgtctggtactttgatgctgaagaaagggcagaa gccaaaaagaaattcaggaatttaactaggaaaactgaatctgccctcactgaagactga |
Protein Sequence |
>112399 : length: 239 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQ LAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKA MVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEP IFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED |