| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 144165 |
Name | PRICKLE1 |
Synonym | EPM1B|RILP;prickle homolog 1 (Drosophila);PRICKLE1;prickle homolog 1 (Drosophila) |
Definition | REST (RE-1 silencing transcription factor)/NRSF (neuron-restrictive silencer factor)-interacting LIM domain protein|REST/NRSF-interacting LIM domain protein 1|prickle-like 1|prickle-like protein 1 |
Position | 12q12 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 13316 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Disease | Heart failure;NHGRI |
Disease | Epilepsy, progressive myoclonic 1B;OMIM |
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External Links |
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Links to Entrez Gene | 144165 |
Links to all GeneRIF Items | 144165 |
Links to iHOP | 144165 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>144165 : length: 2496 atgcctttggagatggagcccaagatgagcaaactggcctttggctgtcagagaagttcc acatcagatgatgactctggctgtgcattggaggagtacgcctgggtccccccgggcctg agaccagagcagatccagctctattttgcttgcttaccagaggaaaaagttccttacgtt aacagccccggagagaagcatcggattaaacagcttttgtaccagttaccaccacatgat aatgaggtacggtattgccagtctttgagtgaagaggagaaaaaagagttgcaggtgttc agtgctcagcggaagaaagaagcactgggaagaggaacaattaagcttctgtccagagca gtcatgcatgctgtgtgtgagcagtgtggtttgaagataaatggaggtgaagttgcagtg ttcgcctcccgtgcgggccctggtgtgtgctggcacccatcctgttttgtctgtttcacg tgtaatgagctgctggtcgacctcatctatttttatcaggatggaaaaattcactgtggc aggcaccatgcagaactgctcaaaccacggtgctcagcatgtgacgagataatttttgct gatgagtgcacagaagctgagggtcgccattggcacatgaaacacttctgctgccttgag tgtgaaacggtcctgggaggacagaggtatatcatgaaggacggccgccccttctgctgt ggctgttttgagtctctctatgcggagtactgtgaaacctgtggggaacatattggtgtg gaccatgcacagatgacctatgacgggcagcactggcacgccacggaagcctgcttttct tgtgcccagtgtaaagcctctttgttgggatgtcccttccttcccaaacagggtcagatt tactgctcaaaaacgtgcagtcttggtgaagacgtccatgcctctgattcttccgactct gcatttcagtcagctcgatcaagagactcccgaagaagtgtccgaatgggcaagagcagc cggtcagcagatcagtgtagacagtctctcctcttatcgcctgctctgaactacaagttt cctggcctctcaggcaatgctgatgacaccctttctcgaaaattggatgatctgagtctc tccagacaaggaacaagttttgccagtgaagaattttggaaaggcagagtagagcaggaa actccagaagaccctgaagaatgggctgatcatgaagattatatgacgcagctcctcctc aagtttggtgataaaagcctctttcagccacagcccaatgagatggatattcgagccagt gagcactggatatctgataacatggttaaaagtaagaccgagttaaagcaaaataaccag agccttgcaagtaaaaaataccagtctgatatgtactgggcacagtcacaagatggactg ggcgattctgcttatggcagccacccaggccctgcaagcagtagaaggcttcaggaattg gaactggaccatggggcttcagggtataatcatgatgaaacacagtggtatgaagattcc ctggagtgtctgtcagacctgaaaccagagcaaagtgttcgggattcgatggattctttg gcattgtccaatatcacaggggcttcggtggatggagaaaacaagccaaggccatcattg tattctctgcaaaattttgaggagatggaaacagaagattgtgagaagatgagcaatatg ggaactttgaactcttccatgctgcacaggagtgcagagtccttaaagagtctaagttca gagttgtgtccagagaaaatcctgcctgaagagaagccagtacatctgccagtgctcaga aggtccaagtctcaatccagaccccagcaggtcaagttttctgatgatgtcattgacaat gggaactatgacattgaaatccggcagcctccgatgagtgaaaggactcggagacgcgtc tacaattttgaagagaggggatccaggtctcatcaccaccgccgccggagaagtagaaag tcccgctccgacaatgccctgaatcttgttacagaaagaaaatactctcccaaggacaga ctgcggctgtacacccccgataactatgagaaatttatacagaataaaagtgcccgggag atccaagcatacatccagaatgctgatctctacggacagtacgcccatgccacttccgat tatggcctgcagaacccaggaatgaatcggtttctgggactctacggcgaggatgatgat tcctggtgttcttcctcctcctcctcttccgactcggaagaagaaggatattttcttgga caaccaatccctcaaccccggccacagagatttgcctactatacagatgacctttctagt ccaccatctgcacttcccacccctcagtttggtcagaggacaacaaaatccaagaagaaa aagggacacaagggcaaaaattgtattatttcttaa |
Protein Sequence |
>144165 : length: 831 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS |