| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1500 |
Name | CTNND1 |
Synonym | CAS|CTNND|P120CAS|P120CTN|p120|p120(CAS)|p120(CTN);catenin (cadherin-associated protein), delta 1;CTNND1;catenin (cadherin-associated protein), delta 1 |
Definition | cadherin-associated Src substrate|catenin delta-1|p120 catenin |
Position | 11q11 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 163 |
TUSON P-value | 0.000319297 |
|
Pathways and Diseases |
|
Pathway | Cell junction organization;Reactome;REACT:20676 |
Pathway | Adherens junction;KEGG PATHWAY;hsa04520 |
Pathway | N-cadherin signaling events;PID Curated;200180 |
Pathway | Adherens junctions interactions;PID Reactome;500120 |
Pathway | Arf6 trafficking events;PID Curated;200046 |
Pathway | Cadherin signaling pathway;PANTHER;P00012 |
Pathway | Leukocyte transendothelial migration;KEGG PATHWAY;hsa04670 |
Pathway | E-cadherin signaling in the nascent adherens junction;PID Curated;200105 |
Pathway | Stabilization and expansion of the E-cadherin adherens junction;PID Curated;200155 |
Pathway | E-cadherin signaling in keratinocytes;PID Curated;200125 |
Pathway | FGF signaling pathway;PID Curated;200189 |
Disease | Cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 1500 |
Links to all GeneRIF Items | 1500 |
Links to iHOP | 1500 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>1500 : length: 2907 atggacgactcagaggtggagtcgaccgccagcatcttggcctctgtgaaggaacaagag gcccagtttgagaagctgacccgggcgctggaggaggaacggcgccacgtctcggcgcag ctggaacgcgtccgggtctcaccacaagatgccaacccactcatggccaacggcacactc acccgccggcatcagaacggccggtttgtgggcgatgctgaccttgaaagacagaaattt tcagatttgaaactcaacggaccccaggatcacagtcaccttctatatagcaccatcccc aggatgcaggagccggggcagattgtggagacctacacggaggaggatcctgagggagcc atgtctgtagtctctgtggagacctcagatgatgggaccactcggcgcacagagaccacg gtcaagaaagtagtgaagactgtgacaacacggacagtacagccagtcgctatgggacca gacgggttgcctgtggatgcttcatcagtttctaacaactatatccagactttgggtcgt gatttccgcaagaatggcaatgggggacctggtccctatgtggggcaagctggcactgct acccttcctaggaacttccactaccctcctgatggttatagtcgccactatgaagatggt tatccaggtggcagtgataactatggcagtctgtcccgggtgacccgcattgaggagcgg tataggcccagcatggaaggctaccgggcacctagtagacaggatgtgtatgggccccaa ccccaggttcgggtaggtgggagcagcgtggatctgcatcgctttcatccagagccttat gggctagaggatgaccagcgtagtatgggctatgatgacctggattatggtatgatgtct gattatggcactgcccgtcggactgggacaccctctgaccctcgtcggcgcctcaggagc tatgaagacatgattggtgaggaggtgccatcggatcaatactactgggctcctttggcc cagcatgagcgaggaagtttagcaagcttggatagcctgcgcaaaggagggcctccacct cctaattggagacagccagagctgccagaggtgatcgccatgcttggattccgcttggat gctgtcaagtccaatgcagctgcatacctgcaacacttatgctaccgcaatgacaaggtg aagactgacgtgcggaagctcaagggcatcccagtactggtgggattgttagaccatccc aaaaaggaagtgcaccttggagcctgtggagctctcaagaatatctcttttggacgtgac caggataacaagattgccataaaaaactgtgatggtgtgcctgcccttgtgcgattgctt cgaaaggctcgtgatatggaccttactgaagttattaccggaaccctgtggaatctttca tcccatgactcaatcaaaatggagattgtggaccatgcactgcatgccttgacagatgaa gtgatcattcctcattctggttgggagcgggaacctaatgaagactgtaagccacgccat attgagtgggaatcggtgctcaccaacacagctggctgccttaggaatgtaagctcagag aggagtgaagctcgccggaaacttcgggaatgtgatggtttagttgatgccctcattttc attgttcaggctgagattgggcagaaggattcagacagcaagcttgtagagaactgtgtt tgccttcttcggaacttatcatatcaagttcaccgggagatcccacaggcagagcgttac caagaggcagctcccaatgttgccaacaatactgggccacatgctgccagttgctttggg gccaagaagggcaaagatgagtggttctccagagggaaaaaacctatagaggatccagca aacgatacagtggatttccctaaaagaacgagtccagctcgaggctatgagctcttattt cagccagaggtggttcggatatacatctcacttcttaaggagagcaagactcctgccatc ctagaagcctcagctggagctatccagaacttgtgtgctgggcgctggacgtatggtcga tacatccgctctgctctgcgtcaagagaaggctctttctgccatagctgacctcctgact aatgaacatgaacgggtggtgaaagctgcatctggagcactgagaaacctggctgtggat gctcgcaacaaagaattaattggtaaacatgctattcctaacttggtaaagaatctgcca ggaggacagcagaactcctcttggaatttctctgaggacactgtcatctctattttgaac actatcaacgaggttatcgctgagaacttggaggctgccaaaaagcttcgagagacacag ggtattgagaagctggtgttgatcaacaaatcagggaaccgctcagaaaaagaagttcga gcagcagcacttgtattacagacaatctggggatataaggaactgcggaagccactggaa aaagaaggatggaagaaatcagactttcaggtgaatctaaacaatgcttcccgaagccag agcagtcattcatatgatgatagtactctccctctcattgaccggaaccaaaaatcagat aagaaacctgatcgggaagaaattcagatgagcaatatgggatcaaacacaaaatcacta gataacaactattccacaccaaatgagagaggagaccacaatagaacactggatcgatcg ggggatctaggcgacatggagccattgaagggaacaacacccttgatgcaggacgagggg caggaatctctggaggaagagttggatgtgttggttttggatgatgaggggggccaagtg tcttacccctccatgcagaagatttag |
Protein Sequence |
>1500 : length: 968 MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTL TRRHQNGRFVGDADLERQKFSDLKLNGPQDHSHLLYSTIPRMQEPGQIVETYTEEDPEGA MSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPDGLPVDASSVSNNYIQTLGR DFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGGSDNYGSLSRVTRIEER YRPSMEGYRAPSRQDVYGPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDLDYGMMS DYGTARRTGTPSDPRRRLRSYEDMIGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPPP PNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHP KKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLS SHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSE RSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERY QEAAPNVANNTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVDFPKRTSPARGYELLF QPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLT NEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILN TINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLE KEGWKKSDFQVNLNNASRSQSSHSYDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSL DNNYSTPNERGDHNRTLDRSGDLGDMEPLKGTTPLMQDEGQESLEEELDVLVLDDEGGQV SYPSMQKI |