| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 2100 |
Name | ESR2 |
Synonym | ER-BETA|ESR-BETA|ESRB|ESTRB|Erb|NR3A2;estrogen receptor 2 (ER beta);ESR2;estrogen receptor 2 (ER beta) |
Definition | estrogen receptor beta|estrogen receptor beta 4|nuclear receptor subfamily 3 group A member 2 |
Position | 14q23.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 6656 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Gene Expression;Reactome;REACT:71 |
Pathway | Plasma membrane estrogen receptor signaling;PID Curated;200029 |
Disease | bulimia;GAD |
Disease | endometriosis;GAD |
Disease | Myasthenia Gravis;FunDO |
Disease | homocysteine nitric oxide;GAD |
Disease | Cancer;FunDO |
Disease | Cholelithiasis;FunDO |
Disease | Parkinson disease;FunDO |
Disease | Glaucoma;FunDO |
Disease | Infertility, Male;GAD |
Disease | bone density fracture risk osteoporosis, postmenopausal;GAD |
Disease | Parkinson's disease;GAD |
Disease | prostate cancer;GAD |
Disease | Dental plaque;FunDO |
Disease | Ptosis;FunDO |
Disease | Schizophrenia;FunDO |
Disease | Alzheimer's disease;FunDO |
Disease | bone density fractures, vertebral;GAD |
Disease | Bone Mineral Density;GAD |
Disease | METABOLIC;GAD |
Disease | bone density;GAD |
Disease | PSYCH;GAD |
Disease | Ovarian disease;FunDO |
Disease | REPRODUCTION;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Late pregnancy;FunDO |
Disease | Testicular dysfunction;FunDO |
Disease | blood pressure;GAD |
Disease | hypospadias;GAD |
Disease | Endometriosis;FunDO |
Disease | NEUROLOGICAL;GAD |
Disease | Hypertension;FunDO |
Disease | blood pressure, arterial;GAD |
Disease | bone mass;GAD |
Disease | hormone disturbance;GAD |
Disease | Osteoporosis;FunDO |
Disease | breast cancer;GAD |
Disease | CANCER;GAD |
Disease | menstrual disorders;GAD |
Disease | cholesterol cholesterol, HDL cholesterol, LDL fatty acid glucose insulin lipoprotein triacylglycerols;GAD |
Disease | Temporal arteritis;FunDO |
Disease | dementia, vascular;GAD |
Disease | Atherosclerosis;FunDO |
|
External Links |
|
Links to Entrez Gene | 2100 |
Links to all GeneRIF Items | 2100 |
Links to iHOP | 2100 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>2100 : length: 1488 atggatataaaaaactcaccatctagccttaattctccttcctcctacaactgcagtcaa tccatcttacccctggagcacggctccatatacataccttcctcctatgtagacagccac catgaatatccagccatgacattctatagccctgctgtgatgaattacagcattcccagc aatgtcactaacttggaaggtgggcctggtcggcagaccacaagcccaaatgtgttgtgg ccaacacctgggcacctttctcctttagtggtccatcgccagttatcacatctgtatgcg gaacctcaaaagagtccctggtgtgaagcaagatcgctagaacacaccttacctgtaaac agagagacactgaaaaggaaggttagtgggaaccgttgcgccagccctgttactggtcca ggttcaaagagggatgctcacttctgcgctgtctgcagcgattacgcatcgggatatcac tatggagtctggtcgtgtgaaggatgtaaggccttttttaaaagaagcattcaaggacat aatgattatatttgtccagctacaaatcagtgtacaatcgataaaaaccggcgcaagagc tgccaggcctgccgacttcggaagtgttacgaagtgggaatggtgaagtgtggctcccgg agagagagatgtgggtaccgccttgtgcggagacagagaagtgccgacgagcagctgcac tgtgccggcaaggccaagagaagtggcggccacgcgccccgagtgcgggagctgctgctg gacgccctgagccccgagcagctagtgctcaccctcctggaggctgagccgccccatgtg ctgatcagccgccccagtgcgcccttcaccgaggcctccatgatgatgtccctgaccaag ttggccgacaaggagttggtacacatgatcagctgggccaagaagattcccggctttgtg gagctcagcctgttcgaccaagtgcggctcttggagagctgttggatggaggtgttaatg atggggctgatgtggcgctcaattgaccaccccggcaagctcatctttgctccagatctt gttctggacagggatgaggggaaatgcgtagaaggaattctggaaatctttgacatgctc ctggcaactacttcaaggtttcgagagttaaaactccaacacaaagaatatctctgtgtc aaggccatgatcctgctcaattccagtatgtaccctctggtcacagcgacccaggatgct gacagcagccggaagctggctcacttgctgaacgccgtgaccgatgctttggtttgggtg attgccaagagcggcatctcctcccagcagcaatccatgcgcctggctaacctcctgatg ctcctgtcccacgtcaggcatgcgagggcagaaaaggcctctcaaacactcacctcattt ggaatgaagatggagactcttttgcctgaagcaacgatggagcagtga |
Protein Sequence |
>2100 : length: 495 MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF GMKMETLLPEATMEQ |