Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

23221

Name

RHOBTB2

Synonym

DBC2;Rho-related BTB domain containing 2;RHOBTB2;Rho-related BTB domain containing 2

Definition

deleted in breast cancer 2 gene protein|p83|rho-related BTB domain-containing protein 2

Position

8p21.3

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

14083

TUSON P-value

1

Pathways and Diseases

Pathway

Signaling by Rho GTPases;Reactome;REACT:11044

Pathway

Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120

External Links

Links to Entrez Gene

23221

Links to all GeneRIF Items

23221

Links to iHOP

23221

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>23221 : length: 2250
atgcaagcctggagaaaaggccccgatggcccccagaagacctcttcagacagcatgtcc
cgtttaatggattctgacatggattatgaaaggccaaacgtagagaccatcaagtgcgtt
gtggtgggggacaacgccgtgggtaagaccaggctcatctgtgcccgcgcttgcaatgcc
accctcacccagtaccagctgctggccacgcatgtgcccacagtatgggccatcgaccaa
tatcgtgtgtgccaggaggtgctggaacgctcccgagacgtggtagatgatgtcagcgtc
tctctgcgcctctgggacacctttggagaccaccacaaagaccgtcgctttgcttatggg
agatctgatgtggtggttctgtgcttctccattgccaaccccaattccctccaccatgtc
aagaccatgtggtacccagaaatcaagcacttctgcccccgagcacctgtcatcttggtg
ggctgccagttggacctgcgctacgctgacctggaggctgtcaacagggctaggcgaccc
ttggctaggcccatcaaacctaatgaaatcctgcccccagagaagggtcgggaggtggcc
aaggagctgggcatcccctactatgagaccagcgtggtggcccagttcggcatcaaggac
gtctttgacaacgccatccgagctgcactcatctcccgccgccacctgcagttctggaag
tcccacctccgcaatgtgcagcggcctctgctgcaggcacccttcctaccccccaagcca
ccgcccccgatcatcgtggtgcccgaccctccctccagcagcgaggagtgccccgcccac
ctcctggaggacccgctctgcgcggacgtcatcctggtgctgcaggagcgggtgcgcatc
tttgcccacaagatctacctctccacctcttcctccaagttctatgacctgttcctcatg
gacctgagtgagggggagctggggggcccctcggagccagggggcacccacccagaggac
caccagggccactctgatcaacaccaccaccatcaccaccaccaccatgggcgagacttc
ctgctccgagcagccagctttgacgtgtgcgagagcgtggatgaggctgggggctccggt
cctgctggcctccgtgcttccaccagcgacgggatcttacggggcaacggaacagggtac
ctaccgggcaggggtcgtgtgctgtcttcctggagccgagcttttgtgagcatccaggaa
gagatggcagaagatcctctcacctacaaatcccggctgatggtggtggtgaagatggac
agttccatccagccggggcccttccgggctgtcctcaagtacctgtacacgggggagcta
gatgagaacgagcgtgacctcatgcacattgcccacattgctgagctgctcgaggtcttt
gatctgcgcatgatggtggccaacattctcaacaatgaggccttcatgaaccaggagatc
accaaggccttccacgtccgccggaccaaccgggttaaggagtgcttggcaaaaggcacc
ttctcagatgtgaccttcatcctggatgatggcaccatcagcgcccacaagcccctgttg
atttccagctgtgactggatggctgccatgtttggggggccatttgtggagagctccacc
cgggaggtggtgtttccctacacaagcaagagctgcatgcgggccgtgctggaatacctc
tacaccggcatgttcacctccagccccgacctggatgacatgaagctcatcattctagcc
aaccgcctctgcctgccacacctggttgccctcacagagcagtacacagtgaccgggctg
atggaagcgacccagatgatggtggacatcgatggggacgtccttgtgttcctggaactg
gctcagttccactgtgcgtaccagctggccgactggtgtctccaccacatctgcaccaac
tacaacaacgtgtgccgcaagttcccccgagacatgaaggccatgtccccagaaaaccag
gagtatttcgagaagcatcggtggccacctgtgtggtacctgaaggaggaagatcattac
cagcgggcacggaaggagcgtgagaaggaggactacctccacctcaagcggcagcccaaa
cggcgttggctcttctggaacagtccatcctccccgtcttcctcggcagcctcctcctca
tccccatcttcctcctcggctgtggtctga

Protein Sequence

>23221 : length: 749
MQAWRKGPDGPQKTSSDSMSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNA
TLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYG
RSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRP
LARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWK
SHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRI
FAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDF
LLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQE
EMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVF
DLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLL
ISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILA
NRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTN
YNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPK
RRWLFWNSPSSPSSSAASSSSPSSSSAVV



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