| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 23405 |
Name | DICER1 |
Synonym | DCR1|Dicer|Dicer1e|HERNA|K12H4.8-LIKE|MNG1|RMSE2;dicer 1, ribonuclease type III;DICER1;dicer 1, ribonuclease type III |
Definition | Dicer1, Dcr-1 homolog|dicer 1, double-stranded RNA-specific endoribonuclease|endoribonuclease Dicer|helicase MOI|helicase with RNAse motif |
Position | 14q32.13 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 5957 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | dicer pathway;PID BioCarta;100188 |
Pathway | MicroRNA (miRNA) Biogenesis;PID Reactome;500366 |
Pathway | Regulatory RNA pathways;Reactome;REACT:12472 |
Disease | Pleuropulmonary blastoma;OMIM |
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External Links |
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Links to Entrez Gene | 23405 |
Links to all GeneRIF Items | 23405 |
Links to iHOP | 23405 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>23405 : length: 5490 atgaaaagccctgctttgcaacccctcagcatggcaggcctgcagctcatgacccctgct tcctcaccaatgggtcctttctttggactgccatggcaacaagaagcaattcatgataac atttatacgccaagaaaatatcaggttgaactgcttgaagcagctctggatcataatacc atcgtctgtttaaacactggctcagggaagacatttattgcagtactactcactaaagag ctgtcctatcagatcaggggagacttcagcagaaatggaaaaaggacggtgttcttggtc aactctgcaaaccaggttgctcaacaagtgtcagctgtcagaactcattcagatctcaag gttggggaatactcaaacctagaagtaaatgcatcttggacaaaagagagatggaaccaa gagtttactaagcaccaggttctcattatgacttgctatgtcgccttgaatgttttgaaa aatggttacttatcactgtcagacattaaccttttggtgtttgatgagtgtcatcttgca atcctagaccacccctatcgagaaattatgaagctctgtgaaaattgtccatcatgtcct cgcattttgggactaactgcttccattttaaatgggaaatgtgatccagaggaattggaa gaaaagattcagaaactagagaaaattcttaagagtaatgctgaaactgcaactgacctg gtggtcttagacaggtatacttctcagccatgtgagattgtggtggattgtggaccattt actgacagaagtgggctttatgaaagactgctgatggaattagaagaagcacttaatttt atcaatgattgtaatatatctgtacattcaaaagaaagagattctactttaatttcgaaa cagatactatcagactgtcgtgccgtattggtagttctgggaccctggtgtgcagataaa gtagctggaatgatggtaagagaactacagaaatacatcaaacatgagcaagaggagctg cacaggaaatttttattgtttacagacactttcctaaggaaaatacatgcactatgtgaa gagcacttctcacctgcctcacttgacctgaaatttgtaactcctaaagtaatcaaactg ctcgaaatcttacgcaaatataaaccatatgagcgacagcagtttgaaagcgttgagtgg tataataatagaaatcaggataattatgtgtcatggagtgattctgaggatgatgatgag gatgaagaaattgaagaaaaagagaagccagagacaaattttccttctccttttaccaac attttgtgcggaattatttttgtggaaagaagatacacagcagttgtcttaaacagattg ataaaggaagctggcaaacaagatccagagctggcttatatcagtagcaatttcataact ggacatggcattgggaagaatcagcctcgcaacaaacagatggaagcagaattcagaaaa caggaagaggtacttaggaaatttcgagcacatgagaccaacctgcttattgcaacaagt attgtagaagagggtgttgatataccaaaatgcaacttggtggttcgttttgatttgccc acagaatatcgatcctatgttcaatctaaaggaagagcaagggcacccatctctaattat ataatgttagcggatacagacaaaataaaaagttttgaagaagaccttaaaacctacaaa gctattgaaaagatcttgagaaacaagtgttccaagtcggttgatactggtgagactgac attgatcctgtcatggatgatgatgacgttttcccaccatatgtgttgaggcctgacgat ggtggtccacgagtcacaatcaacacggccattggacacatcaatagatactgtgctaga ttaccaagtgatccgtttactcatctagctcctaaatgcagaacccgagagttgcctgat ggtacattttattcaactctttatctgccaattaactcacctcttcgagcctccattgtt ggtccaccaatgagctgtgtacgattggctgaaagagttgtagctctcatttgctgtgag aaactgcacaaaattggcgaactggatgaccatttgatgccagttgggaaagagactgtt aaatatgaagaggagcttgatttgcatgatgaagaagagaccagtgttccaggaagacca ggttccacgaaacgaaggcagtgctacccaaaagcaattccagagtgtttgagggatagt tatcccagacctgatcagccctgttacctgtatgtgataggaatggttttaactacacct ttacctgatgaactcaactttagaaggcggaagctctatcctcctgaagataccacaaga tgctttggaatactgacggccaaacccatacctcagattccacactttcctgtgtacaca cgctctggagaggttaccatatccattgagttgaagaagtctggtttcatgttgtctcta caaatgcttgagttgattacaagacttcaccagtatatattctcacatattcttcggctt gaaaaacctgcactagaatttaaacctacagacgctgattcagcatactgtgttctacct cttaatgttgttaatgactccagcactttggatattgactttaaattcatggaagatatt gagaagtctgaagctcgcataggcattcccagtacaaagtatacaaaagaaacacccttt gtttttaaattagaagattaccaagatgccgttatcattccaagatatcgcaattttgat cagcctcatcgattttatgtagctgatgtgtacactgatcttaccccactcagtaaattt ccttcccctgagtatgaaacttttgcagaatattataaaacaaagtacaaccttgaccta accaatctcaaccagccactgctggatgtggaccacacatcttcaagacttaatcttttg acacctcgacatttgaatcagaaggggaaagcgcttcctttaagcagtgctgagaagagg aaagccaaatgggaaagtctgcagaataaacagatactggttccagaactctgtgctata catccaattccagcatcactgtggagaaaagctgtttgtctccccagcatactttatcgc cttcactgccttttgactgcagaggagctaagagcccagactgccagcgatgctggcgtg ggagtcagatcacttcctgcggattttagataccctaacttagacttcgggtggaaaaaa tctattgacagcaaatctttcatctcaatttctaactcctcttcagctgaaaatgataat tactgtaagcacagcacaattgtccctgaaaatgctgcacatcaaggtgctaatagaacc tcctctctagaaaatcatgaccaaatgtctgtgaactgcagaacgttgctcagcgagtcc cctggtaagctccacgttgaagtttcagcagatcttacagcaattaatggtctttcttac aatcaaaatctcgccaatggcagttatgatttagctaacagagacttttgccaaggaaat cagctaaattactacaagcaggaaatacccgtgcaaccaactacctcatattccattcag aatttatacagttacgagaaccagccccagcccagcgatgaatgtactctcctgagtaat aaataccttgatggaaatgctaacaaatctacctcagatggaagtcctgtgatggccgta atgcctggtacgacagacactattcaagtgctcaagggcaggatggattctgagcagagc ccttctattgggtactcctcaaggactcttggccccaatcctggacttattcttcaggct ttgactctgtcaaacgctagtgatggatttaacctggagcggcttgaaatgcttggcgac tcctttttaaagcatgccatcaccacatatctattttgcacttaccctgatgcgcatgag ggccgcctttcatatatgagaagcaaaaaggtcagcaactgtaatctgtatcgccttgga aaaaagaagggactacccagccgcatggtggtgtcaatatttgatccccctgtgaattgg cttcctcctggttatgtagtaaatcaagacaaaagcaacacagataaatgggaaaaagat gaaatgacaaaagactgcatgctggcgaatggcaaactggatgaggattacgaggaggag gatgaggaggaggagagcctgatgtggagggctccgaaggaagaggctgactatgaagat gatttcctggagtatgatcaggaacatatcagatttatagataatatgttaatggggtca ggagcttttgtaaagaaaatctctctttctcctttttcaaccactgattctgcatatgaa tggaaaatgcccaaaaaatcctccttaggtagtatgccattttcatcagattttgaggat tttgactacagctcttgggatgcaatgtgctatctggatcctagcaaagctgttgaagaa gatgactttgtggtggggttctggaatccatcagaagaaaactgtggtgttgacacggga aagcagtccatttcttacgacttgcacactgagcagtgtattgctgacaaaagcatagcg gactgtgtggaagccctgctgggctgctatttaaccagctgtggggagagggctgctcag cttttcctctgttcactggggctgaaggtgctcccggtaattaaaaggactgatcgggaa aaggccctgtgccctactcgggagaatttcaacagccaacaaaagaacctttcagtgagc tgtgctgctgcttctgtggccagttcacgctcttctgtattgaaagactcggaatatggt tgtttgaagattccaccaagatgtatgtttgatcatccagatgcagataaaacactgaat caccttatatcggggtttgaaaattttgaaaagaaaatcaactacagattcaagaataag gcttaccttctccaggcttttacacatgcctcctaccactacaatactatcactgattgt taccagcgcttagaattcctgggagatgcgattttggactacctcataaccaagcacctt tatgaagacccgcggcagcactccccgggggtcctgacagacctgcggtctgccctggtc aacaacaccatctttgcatcgctggctgtaaagtacgactaccacaagtacttcaaagct gtctctcctgagctcttccatgtcattgatgactttgtgcagtttcagcttgagaagaat gaaatgcaaggaatggattctgagaaaagttttctgcaaatgtaccccgttcccctgtgc gagaattgcttgaaatggaaccagaaactgccaaatttagcccggctgagagaacttacg acgggaaggtcagagtcactgtggaagtag |
Protein Sequence |
>23405 : length: 1829 MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNT IVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSANQVAQQVSAVRTHSDLK VGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHLA ILDHPYREIMKLCENCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDL VVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEEALNFINDCNISVHSKERDSTLISK QILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCE EHFSPASLDLKFVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDE DEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFIT GHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLP TEYRSYVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDTGETD IDPVMDDDDVFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPD GTFYSTLYLPINSPLRASIVGPPMSCVRLAERVVALICCEKLHKIGELDDHLMPVGKETV KYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYPRPDQPCYLYVIGMVLTTP LPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSL QMLELITRLHQYIFSHILRLEKPALEFKPTDADSAYCVLPLNVVNDSSTLDIDFKFMEDI EKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKF PSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKR KAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGV GVRSLPADFRYPNLDFGWKKSIDSKSFISISNSSSAENDNYCKHSTIVPENAAHQGANRT SSLENHDQMSVNCRTLLSESPGKLHVEVSADLTAINGLSYNQNLANGSYDLANRDFCQGN QLNYYKQEIPVQPTTSYSIQNLYSYENQPQPSDECTLLSNKYLDGNANKSTSDGSPVMAV MPGTTDTIQVLKGRMDSEQSPSIGYSSRTLGPNPGLILQALTLSNASDGFNLERLEMLGD SFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNW LPPGYVVNQDKSNTDKWEKDEMTKDCMLANGKLDEDYEEEDEEEESLMWRAPKEEADYED DFLEYDQEHIRFIDNMLMGSGAFVKKISLSPFSTTDSAYEWKMPKKSSLGSMPFSSDFED FDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQCIADKSIA DCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTDREKALCPTRENFNSQQKNLSVS CAAASVASSRSSVLKDSEYGCLKIPPRCMFDHPDADKTLNHLISGFENFEKKINYRFKNK AYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALV NNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSEKSFLQMYPVPLC ENCLKWNQKLPNLARLRELTTGRSESLWK |