| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 23410 |
Name | SIRT3 |
Synonym | SIR2L3;sirtuin 3;SIRT3;sirtuin 3 |
Definition | NAD-dependent deacetylase sirtuin-3, mitochondrial|NAD-dependent protein deacetylase sirtuin-3, mitochondrial|SIR2-like protein 3|mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase|regulatory protein SIR2 homolog 3|silent mating type in |
Position | 11p15.5 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 14963 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Signaling events mediated by HDAC Class III;PID Curated;200020 |
Disease | longevity;GAD |
Disease | AGING;GAD |
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External Links |
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Links to Entrez Gene | 23410 |
Links to all GeneRIF Items | 23410 |
Links to iHOP | 23410 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>23410 : length: 774 atggtgggggccggcatcagcacacccagtggcattccagacttcagatcgccggggagt ggcctgtacagcaacctccagcagtacgatctcccgtaccccgaggccatttttgaactc ccattcttctttcacaaccccaagccctttttcactttggccaaggagctgtaccctgga aactacaagcccaacgtcactcactactttctccggctgcttcatgacaaggggctgctt ctgcggctctacacgcagaacatcgatgggcttgagagagtgtcgggcatccctgcctca aagctggttgaagctcatggaacctttgcctctgccacctgcacagtctgccaaagaccc ttcccaggggaggacattcgggctgacgtgatggcagacagggttccccgctgcccggtc tgcaccggcgttgtgaagcccgacattgtgttctttggggagccgctgccccagaggttc ttgctgcatgtggttgatttccccatggcagatctgctgctcatccttgggacctccctg gaggtggagccttttgccagcttgaccgaggccgtgcggagctcagttccccgactgctc atcaaccgggacttggtggggcccttggcttggcatcctcgcagcagggacgtggcccag ctgggggacgtggttcacggcgtggaaagcctagtggagcttctgggctggacagaagag atgcgggaccttgtgcagcgggaaactgggaagcttgatggaccagacaaatag |
Protein Sequence |
>23410 : length: 257 MVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPG NYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRP FPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSL EVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEE MRDLVQRETGKLDGPDK |