| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 27165 |
Name | GLS2 |
Synonym | GA|GLS|LGA|hLGA;glutaminase 2 (liver, mitochondrial);GLS2;glutaminase 2 (liver, mitochondrial) |
Definition | L-glutamine amidohydrolase|breast cell glutaminase|glutaminase I|glutaminase liver isoform, mitochondrial|phosphate-activated glutaminase|phosphate-dependent glutaminase |
Position | 12q13.3 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 7768 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | superpathway of citrulline metabolism;BioCyc;PWY-5004 |
Pathway | Alanine, aspartate and glutamate metabolism;KEGG PATHWAY;hsa00250 |
Pathway | Nitrogen metabolism;KEGG PATHWAY;hsa00910 |
Pathway | Arginine and proline metabolism;KEGG PATHWAY;hsa00330 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Metabolism of amino acids and derivatives;Reactome;REACT:13 |
Pathway | Synaptic Transmission;Reactome;REACT:13685 |
Pathway | Proximal tubule bicarbonate reclamation;KEGG PATHWAY;hsa04964 |
Pathway | citrulline biosynthesis;BioCyc;CITRULBIO-PWY |
Pathway | D-Glutamine and D-glutamate metabolism;KEGG PATHWAY;hsa00471 |
Disease | Brain disease;FunDO |
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External Links |
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Links to Entrez Gene | 27165 |
Links to all GeneRIF Items | 27165 |
Links to iHOP | 27165 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>27165 : length: 1809 atgcgctccatgaaggctctgcagaaggccctgagccgggctggcagtcactgcgggcga ggaggctggggtcacccgagccggagccccctccttggcgggggcgtccggcaccacctc agtgaggccgcggcgcagggcagagagacgccacacagccaccagccgcagcaccaggat catgattcatcagaaagtggcatgctgtcccgcctgggtgatttgctcttttacactatt gctgaaggacaggaacgaatccctatccacaagttcaccactgcactaaaggccactgga ctgcagacatcagatcctcggctccgagactgcatgagcgagatgcaccgcgtggtccaa gagtccagtagtggtggcctcttggaccgagatctcttccgaaagtgtgtgagcagcaac attgtgctcctgacccaggcattccgaaagaagtttgtcattcctgattttgaggagttc acgggccatgtggatcgcatctttgaggatgtcaaagagctcactggaggcaaagtggca gcctacatccctcagctggccaagtcaaacccagacctgtggggtgtctccctgtgcact gtggatggtcaacggcactctgtgggccacacaaagatccccttctgcctgcagtcctgt gtgaagcccctcacctatgccatctccataagcaccctaggcactgactacgtgcacaag tttgtgggcaaagagccaagtggcctgcgctacaacaagctctccctcaatgaggaagga atcccccataaccccatggtcaatgctggtgccattgttgtcagctccctgatcaagatg gactgtaacaaagcagagaagtttgattttgtgttgcagtatctcaacaaaatggctggg aatgaatacatgggtttcagcaatgccacattccagtcagagaaggaaacaggggatcgg aattatgccatcggctattatctcaaggaaaagaagtgctttcctaagggggtggacatg atggctgcccttgatctctacttccagctgtgttctgtggaggtcacttgtgaatcaggc agtgtcatggcagccaccctcgccaacggtgggatctgccccatcacaggcgagagtgtg ctgagtgctgaagcagtgcgcaacaccctcagcctcatgcattcctgcggcatgtatgac ttctctggccagtttgccttccacgtgggcctgccagccaagtcagctgtatcaggagcc atcctcctggtggtacccaatgtcatgggaatgatgtgcctgtcacccccattggacaag ctggggaacagccatagggggaccagcttctgccagaagttggtgtctctcttcaatttc cacaactatgacaacctgaggcactgtgctcggaagttagacccacggcgtgaaggggca gaaattcggaacaagactgtggtcaacctgttatttgctgcctatagtggcgatgtctca gctcttcgaaggtttgccttgtcagccatggatatggaacagaaagactatgactcgcgc acagctctgcatgttgctgcagctgaaggacacatcgaagttgttaaattcctgatcgag gcttgcaaagtgaatccttttgccaaggacaggtggggcaacattcccctggatgatgct gtgcagttcaaccatctggaggtggtcaaactgcttcaagattaccaggactcctacaca ctctctgaaactcaggctgaggcagcagctgaggccctgtccaaagagaacttagaaagc atggtatga |
Protein Sequence |
>27165 : length: 602 MRSMKALQKALSRAGSHCGRGGWGHPSRSPLLGGGVRHHLSEAAAQGRETPHSHQPQHQD HDSSESGMLSRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLRDCMSEMHRVVQ ESSSGGLLDRDLFRKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDVKELTGGKVA AYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHK FVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAG NEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESG SVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGA ILLVVPNVMGMMCLSPPLDKLGNSHRGTSFCQKLVSLFNFHNYDNLRHCARKLDPRREGA EIRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIE ACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTLSETQAEAAAEALSKENLES MV |