Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

27330

Name

RPS6KA6

Synonym

PP90RSK4|RSK4;ribosomal protein S6 kinase, 90kDa, polypeptide 6;RPS6KA6;ribosomal protein S6 kinase, 90kDa, polypeptide 6

Definition

90 kDa ribosomal protein S6 kinase 6|RSK-4|S6K-alpha 6|S6K-alpha-6|p90-RSK 6|p90RSK6|ribosomal S6 kinase 4|ribosomal protein S6 kinase alpha-6

Position

Xq21

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

14372

TUSON P-value

1

Pathways and Diseases

Pathway

Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722

Pathway

Axon guidance;Reactome;REACT:18266

Pathway

Long-term potentiation;KEGG PATHWAY;hsa04720

Pathway

Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914

Pathway

MAPK signaling pathway;KEGG PATHWAY;hsa04010

Pathway

PDGF signaling pathway;PANTHER;P00047

Pathway

Synaptic Transmission;Reactome;REACT:13685

Pathway

Oocyte meiosis;KEGG PATHWAY;hsa04114

Pathway

Interleukin signaling pathway;PANTHER;P00036

Pathway

mTOR signaling pathway;KEGG PATHWAY;hsa04150

Pathway

Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade;PANTHER;P00032

Pathway

Ras Pathway;PANTHER;P04393

Disease

Breast cancer;FunDO

Disease

Colon cancer;FunDO

External Links

Links to Entrez Gene

27330

Links to all GeneRIF Items

27330

Links to iHOP

27330

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>27330 : length: 2238
atgctaccattcgctcctcaggacgagccctgggaccgagaaatggaagtgttcagcggc
ggcggcgcgagcagcggcgaggtaaatggtcttaaaatggttgatgagccaatggaagag
ggagaagcagattcttgtcatgatgaaggagttgttaaagaaatccctattactcatcat
gttaaggaaggctatgagaaagcagatcctgcacagtttgagttgctcaaggttcttggt
caggggtcatttggaaaggtttttcttgttagaaagaagaccggtcctgatgctgggcag
ctctatgcaatgaaggtgttaaaaaaagcctctttaaaagttcgagacagagttcggaca
aagatggagagggatatactggtggaagtaaatcatccatttattgtcaaattgcactat
gcctttcagactgaagggaaactgtacttaatactggattttctcaggggaggagatgtt
ttcacaagattatccaaagaggttctgtttacagaggaagatgtgaaattctacctcgca
gaactggcccttgctttggatcatctgcaccaattaggaattgtttatagagacctgaag
ccagaaaacattttgcttgatgaaataggacatatcaaattaacagattttggactcagc
aaggagtcagtagatcaagaaaagaaggcttactcattttgtggtacagtagagtatatg
gctcctgaagtagtaaataggagaggccattcccagagtgctgattggtggtcatatggt
gttcttatgtttgaaatgcttactggtactctgccatttcaaggtaaagacagaaatgag
accatgaatatgatattaaaagcaaaacttggaatgcctcaatttcttagtgctgaagca
caaagtcttctaaggatgttattcaaaaggaatccagcaaatagattgggatcagaagga
gttgaagaaatcaaaagacatctgttttttgcaaatattgactgggataaattatataaa
agagaagttcaacctcctttcaaacctgcttctggaaaaccagatgatactttttgtttt
gatcctgaatttactgcaaaaacacctaaagattctcccggtttgccagccagtgcaaat
gctcatcagctcttcaaaggattcagctttgttgcaacttctattgcagaagaatataaa
atcactcctatcacaagtgcaaatgtattaccaattgttcagataaatggaaatgctgca
caatttggtgaagtatatgaattgaaggaggatattggtgttggctcctactctgtttgc
aagcgatgcatacatgcaactaccaacatggaatttgcagtgaagatcattgacaaaagt
aagcgagacccttcagaagagattgaaatattgatgcgctatggacaacatcccaacatt
attactttgaaggatgtctttgatgatggtagatatgtttaccttgttacggatttaatg
aaaggaggagagttacttgaccgtattctcaaacaaaaatgtttctcggaacgggaggct
agtgatatactatatgtaataagtaagacagttgactatcttcattgtcaaggagttgtt
catcgtgatcttaaacctagtaatattttatacatggatgaatcagccagtgcagattca
atcaggatatgtgattttgggtttgcaaaacaacttcgaggagaaaatggacttctctta
actccatgctacactgcaaactttgttgcacctgaggttcttatgcaacagggatatgat
gctgcttgtgatatctggagtttaggagtccttttttacacaatgttggctggctacact
ccatttgctaatggccccaatgatactcctgaagagatactgctgcgtataggcaatgga
aaattctctttgagtggtggaaactgggacaatatttcagacggagcaaaggatttgctt
tcccatatgcttcatatggacccacatcagcggtatactgctgaacaaatattaaagcac
tcatggataactcacagagaccagttgccaaatgatcagccaaagagaaatgatgtgtca
catgttgttaagggagcaatggttgcaacatactctgccctgactcacaagacctttcaa
ccagtcctagagcctgtagctgcttcaagcttagcccagcgacggagcatgaaaaagcga
acatcaactggcctgtaa

Protein Sequence

>27330 : length: 745
MLPFAPQDEPWDREMEVFSGGGASSGEVNGLKMVDEPMEEGEADSCHDEGVVKEIPITHH
VKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRT
KMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLA
ELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYM
APEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEA
QSLLRMLFKRNPANRLGSEGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCF
DPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPITSANVLPIVQINGNAA
QFGEVYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQHPNI
ITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVV
HRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYD
AACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLL
SHMLHMDPHQRYTAEQILKHSWITHRDQLPNDQPKRNDVSHVVKGAMVATYSALTHKTFQ
PVLEPVAASSLAQRRSMKKRTSTGL



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