| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 29072 |
Name | SETD2 |
Synonym | HBP231|HIF-1|HIP-1|HSPC069|HYPB|KMT3A|SET2|p231HBP;SET domain containing 2;SETD2;SET domain containing 2 |
Definition | histone-lysine N-methyltransferase SETD2|huntingtin interacting protein 1|huntingtin yeast partner B|huntingtin-interacting protein B|lysine N-methyltransferase 3A |
Position | 3p21.31 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 15 |
TUSON P-value | 2.23E-32 |
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Pathways and Diseases |
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Pathway | Lysine degradation;KEGG PATHWAY;hsa00310 |
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External Links |
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Links to Entrez Gene | 29072 |
Links to all GeneRIF Items | 29072 |
Links to iHOP | 29072 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>29072 : length: 7695 atgaagcagctgcagccgcagccgcctccgaagatgggggatttctacgacccggagcac ccgacccctgaagaagaagaaaatgaggcaaagattgaaaatgtgcagaaaacaggtttc atcaaaggaccaatgttcaaaggtgttgcttctagtcgatttttgcccaaaggcaccaaa acaaaagttaatttggaagaacagggacgacagaaggtgtcattcagcttcagccttaca aagaaaactttgcagaataggtttctcactgcacttggcaatgaaaagcaaagtgatact ccaaaccctccagctgtacctcttcaggtagactcgactcctaaaatgaaaatggaaatt ggtgataccttatctactgcagaagaatcttccccaccaaagtcaagggtggaattgggc aaaattcattttaagaaacatctgcttcatgtaacatccaggccactgctggctactacc acagcagtagcatctccacctactcatgcagcaccattaccagcagtgatagcagaatca acaactgtagactcaccgccctcatctccgcctccaccgcctccacctgcccaagccaca acactctcatcaccagcaccagtaacagagccagtggccttgccacatacaccaataaca gttctaatggcagcaccagtacccttaccagtagatgtagcagttagatctctgaaagaa ccaccaattataattgtaccagaatctttagaagcagatactaagcaggacactatatct aatagtttagaagaacacgtaactcaaatattgaatgagcaagcagatatttcctcaaaa aaagaagattcccatattgggaaggatgaagaaattccagatagttctaagattagtctg agctgtaaaaaaacaggttctaagaagaaatcctcacaatctgaaggcatctttcttggt tcagaatctgatgaagattctgtacggacttcttcaagtcaaagatcacatgatttaaaa ttttcagcaagcattgaaaaggaaagagattttaaaaagagctcagcacctttaaaaagt gaggatctagggaaaccttcacgatctaaaacagacagagatgataaatattttagctat tcaaaacttgaaagagatactcggtatgtatcttcccgatgtagatcagaaagagagcga cggcggagcagatctcactctaggtctgagagaggctctagaactaatttatcctattcc aggtcagaacgatctcattattatgactctgatcgtcgctaccataggagctccccttat cgagagaggacgcgctattctcggccatacacagataacagagcacgagagagttctgac tcagaagaagagtataagaagacatactcaaggcgtacctcatctcattcctcttcttac agagacctaaggacatcatcctattctaaatctgatcgggactgtaaaactgagacctct tacttagagatggaaagaagaggcaagtattcttcaaaactagaaagagaatctaaaagg acttcagaaaatgaagcaattaaaagatgttgttctccccctaatgaactgggattccga cgagggtcatcatattctaagcatgacagtagtgcttcccgttataaatctaccctttca aaacctatacccaagtctgataaatttaaaaattctttctgttgtacagaattaaatgaa gaaatcaaacagtctcattcttttagtttacagacaccttgttcaaaaggtagtgaatta agaatgattaataaaaatcctgaaagagaaaaggctgggtctccagctccatcaaatcga ttaaatgattcacctactttaaaaaagctagatgaattgcctatttttaagtccgaattt ataacacatgatagccatgatagtattaaggaattagactctttatctaaagtgaagaat gatcaattaagaagtttttgtcccatagaattaaatataaatggatctcctggggcagaa tctgatttggcaacattttgcacttctaaaactgatgctgttttaatgacttctgatgat agtgtgactggatcggaattatcccctttggtcaaagcatgcatgctttcatcaaatgga tttcagaatattagtaggtgcaaagaaaaagacttggatgatacctgcatgctgcataag aagtcagaaagcccatttagagaaacagaacctctggtgtcaccacaccaagataaactc atgtctatgccagttatgactgtggattattccaaaacagtagttaaagaaccagttgat acgagggtttcttgctgcaaaaccaaagattcagacatatactgtactttgaacgatagc aacccttctttgtgtaactctgaagctgaaaatattgagccttcagttatgaagatttct tcaaatagctttatgaatgtgcatttggaatcaaaaccagttatatgtgatagtagaaat ttgacagatcactcaaaatttgcatgtgaagaatataagcagagcatcggtagcactagt tcagcttctgttaatcattttgatgatttatatcaacctattgggagttcaggtattgct tcatctcttcagagtcttccaccaggaataaaggtggacagtctaactctcttgaaatgc ggagagaacacatctccagttctggatgcagtgctaaagagtaaaaaaagttcagagttt ttaaagcatgcagggaaagaaacaatagtagaagtaggtagtgaccttcctgattcagga aagggatttgcttccagggagaacaggcgtaataatgggttatctgggaaatgtttgcaa gaggctcaagaagaagggaattccatattgcctgaaagaagaggaagaccagaaatctct ttagatgaaagaggagaaggaggacatgtgcatacttctgatgactcagaagttgtattt tcttcttgtgatttgaatttaaccatggaagacagtgatggtgtaacttatgcattaaag tgtgacagtagtggtcatgccccagaaattgtgtctacagttcatgaagattattctggc tcttctgaaagttcaaatgatgaaagtgattcagaagatacagattcggatgatagcagt attccaagaaaccgtctccagtctgttgtggttgtgccaaagaattctactttgcccatg gaagaaacaagtccttgttcttctcggagcagtcaaagttatagacactattctgaccat tgggaagatgagagattggagtcaaggagacatttgtatgaggaaaaatttgaaagtata gcaagtaaagcctgtcctcaaactgataagtttttccttcataaaggaacagagaagaat ccggaaatttcttttacacagtccagtagaaaacaaatagataatcgcctgcctgaactt tctcatcctcagagtgatggggttgatagtacaagtcatacagatgtgaaatctgaccct ctgggtcacccaaattcagaggaaaccgtgaaagccaaaataccttctaggcagcaagaa gagctgccaatttattcttctgattttgaagatgtcccaaataagtcttggcaacagacc actttccaaaacaggccagatagtagactgggaaaaacagaattgagtttttcttcctct tgtgagataccacatgtggatggcttgcactcatcagaagagctcagaaacttaggttgg gacttctctcaagaaaagccttctaccacgtatcagcaacctgacagtagctatggagct tgtggtggacacaagtatcagcaaaatgcagaacagtatggtgggacacgtgattactgg caaggcaatggttactgggatccaagatcaggtagacctcctggaactggggttgtgtat gatcgaactcaaggacaagtaccagattccctaacagatgatcgtgaagaagaggagaat tgggatcaacaggatggatcccatttttcagaccagtccgataaatttcttctatccctt cagaaagacaaggggtcagtgcaagcacctgaaataagcagcaattccattaaggacact ttagctgtgaatgaaaagaaagatttttcaaaaaacttagaaaaaaatgatatcaaagat agagggcctcttaaaaaaaggaggcaggaaatagagagtgattctgaaagtgatggtgag cttcaggacagaaagaaagttagagtggaggtagagcagggagagacatcagtgccccca ggttcagcactggttgggccctcctgtgtcatggatgacttcagggacccacagcgatgg aaggaatgtgccaagcaagggaaaatgccatgttactttgatcttattgaagaaaatgtt tatttaacagaaagaaagaagaataaatctcatcgagatattaagcgaatgcagtgtgag tgtacacctctttctaaagatgaaagagctcaaggtgaaatagcatgtggggaagattgt cttaatcgtcttctcatgattgaatgttcttctcggtgtccaaatggggattattgttcc aatagacggtttcagagaaaacagcatgcagatgtggaagtcatactcacagaaaagaaa ggctggggcttgagagctgccaaagaccttccttcgaacacctttgtcctagaatattgt ggagaggtactcgatcataaagagtttaaagctcgagtgaaggagtatgcacgaaacaaa aacatccattactatttcatggccctgaagaatgatgagataatagatgccactcaaaaa ggaaattgctctcgtttcatgaatcacagctgtgaaccaaattgtgaaacccaaaaatgg actgtgaacggacaactgagggttgggttttttaccaccaaactggttccttcaggctca gagttaacgtttgactatcagttccagagatatggaaaagaagcccagaaatgtttctgc ggatcagccaattgccggggttacctgggaggagaaaacagagtcagcatcagagcagca ggagggaaaatgaagaaggaacgatctcgtaagaaggattcagtggatggagagctagaa gctctgatggaaaatggtgagggtctctctgataaaaaccaggtgctcagcttatcccgg ctaatggttagaattgaaactttggagcagaaacttacctgtctggaactcatacagaac acacactcacagtcctgcctgaagtcctttctggaacgtcatgggctgtctttgttgtgg atctggatggcagagctaggtgacggccgggaaagtaaccagaagcttcaggaagagatt ataaagactttggaacacttgcccattcctactaaaaatatgttggaggaaagcaaagta cttccaattattcaacgctggtctcagactaagactgctgtccctccgttgagtgaagga gatgggtattctagtgagaatacatcgcgtgctcatacaccactcaacacacctgatcct tccaccaagctgagcacagaagctgacacagacactcccaagaaactaatgtttcgcaga ctgaaaattataagtgaaaatagcatggacagtgcaatctctgatgcaaccagtgagcta gaaggcaaggatggcaaagaggatcttgatcaattagaaaatgtccctgtagaggaagag gaagaattgcagtcacaacagctactcccacaacagctgcctgaatgcaaagttgatagt gaaaccaacatagaagctagtaagctacctacatctgaaccagaagctgacgctgaaata gagcccaaagagagcaacggcacaaaactagaagaacctattaatgaagaaacaccatcc caagatgaagaggagggtgtgtctgatgtggagagtgaaaggagccaagaacagccagat aaaacagtggatataagtgatttggccaccaaactcctggacagttggaaagacctaaag gaggtatatcgaattccaaagaaaagtcaaactgaaaaggaaaacacaacaactgaacga ggaagggatgctgttggcttcagagatcaaacacctgccccgaagactcctaataggtca agagagagagacccagacaagcaaactcaaaataaagagaaaaggaaacgaagaagctcc ctctcaccaccctcttctgcctatgagcggggaacaaaaaggccagatgacagatatgat acaccaacttctaaaaagaaagtacgaattaaagaccgcaataaactttctacagaggaa cgccggaagttgtttgagcaagaggtggctcaacgggaggctcagaaacaacagcaacag atgcagaacctgggaatgacatcaccactgccctatgactctcttggttataatgccccg catcatccctttgctggttacccaccaggttatcccatgcaggcctatgtggatcccagc aaccctaatgctggaaaggtgctcctgcccacacccagcatggacccagtgtgttctcct gctccttatgatcatgctcagcccttggtgggacattctacagaacccctttctgcccct ccaccagtaccagtggtgccacatgtggcagctcctgtggaagtttccagttcccagtat gtggcccagagtgatggtgtagtacaccaagactccagcgttgctgtcttgccagtgccg gcccccggcccagttcagggacagaattatagtgtttgggattcaaaccaacagtctgtc agtgtacagcagcagtactctcctgcacagtctcaagcaaccatatattatcaaggacag acatgtccaacagtctatggtgtgacatcaccttattcacagacaactccaccaattgta cagagttatgcccagccaagtcttcagtatatccaggggcaacagattttcacagctcat ccacaaggagtggtggtacagccagccgcagcagtgactacaatagttgcaccagggcag cctcagcccttgcagccatctgaaatggttgtgacaaataatctcttggatctgccgccc ccctctcctcccaaaccaaaaaccattgtcttacctcccaactggaagacagctcgagat ccagaagggaagatttattactaccatgtgatcacaaggcagactcagtgggatcctcct acttgggaaagcccaggagatgatgccagccttgagcatgaagctgagatggacctggga actccaacatatgatgaaaaccccatgaaggcctcgaaaaagcccaagacagcagaagca gacacctccagtgaactagcaaagaaaagcaaagaagtattcagaaaagagatgtcccag ttcatcgtccagtgcctgaacccttaccggaaacctgactgcaaagtgggaagaattacc acaactgaagactttaaacatctggctcgcaagctgactcacggtgttatgaataaggag ctgaagtactgtaagaatcctgaggacctggagtgcaatgagaatgtgaaacacaaaacc aaggagtacattaagaagtacatgcagaagtttggggctgtttacaaacccaaagaggac actgaattagagtga |
Protein Sequence |
>29072 : length: 2564 MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTK TKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEI GDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAES TTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKE PPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISL SCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKS EDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYS RSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSY RDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFR RGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSEL RMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKN DQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNG FQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVD TRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRN LTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKC GENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQ EAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALK CDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPM EETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKN PEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQE ELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGW DFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVY DRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDT LAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPP GSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCE CTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKK GWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQK GNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFC GSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSR LMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEI IKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDP STKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEE EELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINEETPS QDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTTTER GRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRPDDRYD TPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLGYNAP HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEPLSAP PPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSVWDSNQQSV SVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAH PQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARD PEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPKTAEA DTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKE LKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE |