| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 2984 |
Name | GUCY2C |
Synonym | DIAR6|GUC2C|MECIL|MUCIL|STAR;guanylate cyclase 2C;GUCY2C;guanylate cyclase 2C |
Definition | GC-C|STA receptor|guanylyl cyclase C|hSTAR|heat stable enterotoxin receptor|heat-stable enterotoxin receptor|intestinal guanylate cyclase |
Position | 12p12 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 8164 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Purine metabolism;KEGG PATHWAY;hsa00230 |
Pathway | actions of nitric oxide in the heart;PID BioCarta;100094 |
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External Links |
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Links to Entrez Gene | 2984 |
Links to all GeneRIF Items | 2984 |
Links to iHOP | 2984 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>2984 : length: 3222 atgaagacgttgctgttggacttggctttgtggtcactgctcttccagcccgggtggctg tcctttagttcccaggtgagtcagaactgccacaatggcagctatgaaatcagcgtcctg atgatgggcaactcagcctttgcagagcccctgaaaaacttggaagatgcggtgaatgag gggctggaaatagtgagaggacgtctgcaaaatgctggcctaaatgtgactgtgaacgct actttcatgtattcggatggtctgattcataactcaggcgactgccggagtagcacctgt gaaggcctcgacctactcaggaaaatttcaaatgcacaacggatgggctgtgtcctcata gggccctcatgtacatactccaccttccagatgtaccttgacacagaattgagctacccc atgatctcagctggaagttttggattgtcatgtgactataaagaaaccttaaccaggctg atgtctccagctagaaagttgatgtacttcttggttaacttttggaaaaccaacgatctg cccttcaaaacttattcctggagcacttcgtatgtttacaagaatggtacagaaactgag gactgtttctggtaccttaatgctctggaggctagcgtttcctatttctcccacgaactc ggctttaaggtggtgttaagacaagataaggagtttcaggatatcttaatggaccacaac aggaaaagcaatgtgattattatgtgtggtggtccagagttcctctacaagctgaagggt gaccgagcagtggctgaagacattgtcattattctagtggatcttttcaatgaccagtac tttgaggacaatgtcacagcccctgactatatgaaaaatgtccttgttctgacgctgtct cctgggaattcccttctaaatagctctttctccaggaatctatcaccaacaaaacgagac tttgctcttgcctatttgaatggaatcctgctctttggacatatgctgaagatatttctt gaaaatggagaaaatattaccacccccaaatttgctcatgctttcaggaatctcactttt gaagggtatgacggtccagtgaccttggatgactggggggatgttgacagtaccatggtg cttctgtatacctctgtggacaccaagaaatacaaggttcttttgacctatgatacccac gtaaataagacctatcctgtggatatgagccccacattcacttggaagaactctaaactt cctaatgatattacaggccggggccctcagatcctgatgattgcagtcttcaccctcact ggagctgtggtgctgctcctgctcgtcgctctcctgatgctcagaaaatatagaaaagat tatgaacttcgtcagaaaaaatggtcccacattcctcctgaaaatatctttcctctggag accaatgagaccaatcatgttagcctcaagatcgatgatgacaaaagacgagatacaatc cagagactacgacagtgcaaatacgacaaaaagcgagtgattctcaaagatctcaagcac aatgatggtaatttcactgaaaaacagaagatagaattgaacaagttgcttcagattgac tattacaacctgaccaagttctacggcacagtgaaacttgataccatgatcttcggggtg atagaatactgtgagagaggatccctccgggaagttttaaatgacacaatttcctaccct gatggcacattcatggattgggagtttaagatctctgtcttgtatgacattgctaaggga atgtcatatctgcactccagtaagacagaagtccatggtcgtctgaaatctaccaactgc gtagtggacagtagaatggtggtgaagatcactgattttggctgcaattccattttacct ccaaaaaaggacctgtggacagctccagagcacctccgccaagccaacatctctcagaaa ggagatgtgtacagctatgggatcatcgcacaggagatcatcctgcggaaagaaaccttc tacactttgagctgtcgggaccggaatgagaagattttcagagtggaaaattccaatgga atgaaacccttccgcccagatttattcttggaaacagcagaggaaaaagagctagaagtg tacctacttgtaaaaaactgttgggaggaagatccagaaaagagaccagatttcaaaaaa attgagactacacttgccaagatatttggactttttcatgaccaaaaaaatgaaagctat atggataccttgatccgacgtctacagctatattctcgaaacctggaacatctggtagag gaaaggacacagctgtacaaggcagagagggacagggctgacagacttaactttatgttg cttccaaggctagtggtaaagtctctgaaggagaaaggctttgtggagccggaactatat gaggaagttacaatctacttcagtgacattgtaggtttcactactatctgcaaatacagc acccccatggaagtggtggacatgcttaatgacatctataagagttttgaccacattgtt gatcatcatgatgtctacaaggtggaaaccatcggtgatgcgtacatggtggctagtggt ttgcctaagagaaatggcaatcggcatgcaatagacattgccaagatggccttggaaatc ctcagcttcatggggacctttgagctggagcatcttcctggcctcccaatatggattcgc attggagttcactctggtccctgtgctgctggagttgtgggaatcaagatgcctcgttat tgtctatttggagatacggtcaacacagcctctaggatggaatccactggcctccctttg agaattcacgtgagtggctccaccatagccatcctgaagagaactgagtgccagttcctt tatgaagtgagaggagaaacatacttaaagggaagaggaaatgagactacctactggctg actgggatgaaggaccagaaattcaacctgccaacccctcctactgtggagaatcaacag cgtttgcaagcagaattttcagacatgattgccaactctttacagaaaagacaggcagca gggataagaagccaaaaacccagacgggtagccagctataaaaaaggcactctggaatac ttgcagctgaataccacagacaaggagagcacctatttttaa |
Protein Sequence |
>2984 : length: 1073 MKTLLLDLALWSLLFQPGWLSFSSQVSQNCHNGSYEISVLMMGNSAFAEPLKNLEDAVNE GLEIVRGRLQNAGLNVTVNATFMYSDGLIHNSGDCRSSTCEGLDLLRKISNAQRMGCVLI GPSCTYSTFQMYLDTELSYPMISAGSFGLSCDYKETLTRLMSPARKLMYFLVNFWKTNDL PFKTYSWSTSYVYKNGTETEDCFWYLNALEASVSYFSHELGFKVVLRQDKEFQDILMDHN RKSNVIIMCGGPEFLYKLKGDRAVAEDIVIILVDLFNDQYFEDNVTAPDYMKNVLVLTLS PGNSLLNSSFSRNLSPTKRDFALAYLNGILLFGHMLKIFLENGENITTPKFAHAFRNLTF EGYDGPVTLDDWGDVDSTMVLLYTSVDTKKYKVLLTYDTHVNKTYPVDMSPTFTWKNSKL PNDITGRGPQILMIAVFTLTGAVVLLLLVALLMLRKYRKDYELRQKKWSHIPPENIFPLE TNETNHVSLKIDDDKRRDTIQRLRQCKYDKKRVILKDLKHNDGNFTEKQKIELNKLLQID YYNLTKFYGTVKLDTMIFGVIEYCERGSLREVLNDTISYPDGTFMDWEFKISVLYDIAKG MSYLHSSKTEVHGRLKSTNCVVDSRMVVKITDFGCNSILPPKKDLWTAPEHLRQANISQK GDVYSYGIIAQEIILRKETFYTLSCRDRNEKIFRVENSNGMKPFRPDLFLETAEEKELEV YLLVKNCWEEDPEKRPDFKKIETTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVE ERTQLYKAERDRADRLNFMLLPRLVVKSLKEKGFVEPELYEEVTIYFSDIVGFTTICKYS TPMEVVDMLNDIYKSFDHIVDHHDVYKVETIGDAYMVASGLPKRNGNRHAIDIAKMALEI LSFMGTFELEHLPGLPIWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPL RIHVSGSTIAILKRTECQFLYEVRGETYLKGRGNETTYWLTGMKDQKFNLPTPPTVENQQ RLQAEFSDMIANSLQKRQAAGIRSQKPRRVASYKKGTLEYLQLNTTDKESTYF |