| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 3175 |
Name | ONECUT1 |
Synonym | HNF-6|HNF6|HNF6A;one cut homeobox 1;ONECUT1;one cut homeobox 1 |
Definition | hepatocyte nuclear factor 6|hepatocyte nuclear factor 6, alpha|one cut domain family member 1 |
Position | 15q21.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 11791 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells;PID Reactome;500520 |
Pathway | Regulation of beta-cell development;PID Reactome;500518 |
Pathway | Maturity onset diabetes of the young;KEGG PATHWAY;hsa04950 |
Pathway | FOXM1 transcription factor network;PID Curated;200120 |
Pathway | Regulation of beta-cell development;Reactome;REACT:13698 |
Pathway | Regulation of gene expression in early pancreatic precursor cells;PID Reactome;500519 |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 3175 |
Links to all GeneRIF Items | 3175 |
Links to iHOP | 3175 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3175 : length: 1398 atgaacgcgcagctgaccatggaagcgatcggcgagctgcacggggtgagccatgagccg gtgcccgcccctgccgacctgctgggcggcagcccccacgcgcgcagctccgtggcgcac cgcggcagccacctgccccccgcgcacccgcgctccatgggcatggcgtccctgctggac ggcggcagcggcggcggagattaccaccaccaccaccgggcccctgagcacagcctggcc ggccccctgcatcccaccatgaccatggcctgcgagactcccccaggtatgagcatgccc accacctacaccaccttgacccctctgcagccgctgcctcccatctccacagtctcggac aagttcccccaccatcaccaccaccaccatcaccaccaccacccgcaccaccaccagcgc ctggcgggcaacgtgagcggtagcttcacgctcatgcgggatgagcgcgggctggcctcc atgaataacctctataccccctaccacaaggacgtggccggcatgggccagagcctctcg cccctctccagctccggtctgggcagcatccacaactcccagcaagggctcccccactat gcccacccgggggccgccatgcccaccgacaagatgctcacccccaacggcttcgaagcc caccacccggccatgctcggccgccacggggagcagcacctcacgcccacctcggccggc atggtgcccatcaacggccttcctccgcaccatccccacgcccacctgaacgcccagggc cacgggcaactcctgggcacagcccgggagcccaacccttcggtgaccggcgcgcaggtc agcaatggaagtaattcagggcagatggaagagatcaataccaaagaggtggcgcagcgt atcaccaccgagctcaagcgctacagcatcccacaggccatcttcgcgcagagggtgctc tgccgctcccaggggaccctctcggacctgctgcgcaaccccaaaccctggagcaaactc aaatccggccgggagaccttccggaggatgtggaagtggctgcaggagccggagttccag cgcatgtccgcgctccgcttagcagcatgcaaaaggaaagaacaagaacatgggaaggat agaggcaacacacccaaaaagcccaggttggtcttcacagatgtccagcgtcgaactcta catgcaatattcaaggaaaataagcgtccatccaaagaattgcaaatcaccatttcccag cagctggggttggagctgagcactgtcagcaacttcttcatgaacgcaagaaggaggagt ctggacaagtggcaggacgagggcagctccaattcaggcaactcatcttcttcatcaagc acttgtaccaaagcatga |
Protein Sequence |
>3175 : length: 465 MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLD GGSGGGDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSD KFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLS PLSSSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAG MVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQR ITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQ RMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQ QLGLELSTVSNFFMNARRRSLDKWQDEGSSNSGNSSSSSSTCTKA |