| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3394 |
Name | IRF8 |
Synonym | H-ICSBP|ICSBP|ICSBP1|IMD32A|IMD32B|IRF-8;interferon regulatory factor 8;IRF8;interferon regulatory factor 8 |
Definition | interferon consensus sequence binding protein 1 |
Position | 16q24.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 9031 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Validated targets of C-MYC transcriptional repression;PID Curated;200171 |
Pathway | GMCSF-mediated signaling events;PID Curated;200015 |
Disease | Carcinoma;FunDO |
Disease | Diabetes mellitus;FunDO |
Disease | multiple sclerosis;GAD |
Disease | IMMUNE;GAD |
Disease | Infection;FunDO |
Disease | Chronic lymphocytic leukemia;NHGRI |
Disease | Chronic lymphocytic leukemia;GAD |
Disease | Lymphoma;FunDO |
Disease | Leukemia;FunDO |
Disease | CANCER;GAD |
Disease | Multiple sclerosis;NHGRI |
|
External Links |
|
Links to Entrez Gene | 3394 |
Links to all GeneRIF Items | 3394 |
Links to iHOP | 3394 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3394 : length: 1281 atgtgtgaccggaatggtggtcggcggcttcgacagtggctgatcgagcagattgacagt agcatgtatccaggactgatttgggagaatgaggagaagagcatgttccggatcccttgg aaacacgctggcaagcaagattataatcaggaagtggatgcctccatttttaaggcctgg gcagtttttaaagggaagtttaaagaaggggacaaagctgaaccagccacttggaagacg aggttacgctgtgctttgaataagagcccagattttgaggaagtgacggaccggtcccaa ctggacatttccgagccatacaaagtttaccgaattgttcctgaggaagagcaaaaatgc aaactaggcgtggcaactgctggctgcgtgaatgaagttacagagatggagtgcggtcgc tctgaaatcgacgagctgatcaaggagccttctgtggacgattacatggggatgatcaaa aggagcccttccccgccggaggcctgtcggagtcagctccttccagactggtgggcgcag cagcccagcacaggcgtgccgctggtgacggggtacaccacctacgacgcgcaccattca gcattctcccagatggtgatcagcttctactatgggggcaagctggtgggccaggccacc accacctgccccgagggctgccgcctgtccctgagccagcctgggctgcccggcaccaag ctgtatgggcccgagggcctggagctggtgcgcttcccgccggccgacgccatccccagc gagcgacagaggcaggtgacgcggaagctgttcgggcacctggagcgcggggtgctgctg cacagcagccggcagggcgtgttcgtcaagcggctgtgccagggccgcgtgttctgcagc ggcaacgccgtggtgtgcaaaggcaggcccaacaagctggagcgtgatgaggtggtccag gtcttcgacaccagccagttcttccgagagctgcagcagttctataacagccagggccgg cttcctgacggcagggtggtgctgtgctttggggaagagtttccggatatggcccccttg cgctccaaactcattctcgtgcagattgagcagctgtatgtccggcaactggcagaagag gctgggaagagctgtggagccggctctgtgatgcaggcccccgaggagccgccgccagac caggtcttccggatgtttccagatatttgtgcctcacaccagagatcatttttcagagaa aaccaacagatcaccgtctaa |
Protein Sequence |
>3394 : length: 426 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAW AVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKC KLGVATAGCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSPPEACRSQLLPDWWAQ QPSTGVPLVTGYTTYDAHHSAFSQMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTK LYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCS GNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPL RSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRE NQQITV |