| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 3417 |
Name | IDH1 |
Synonym | HEL-216|HEL-S-26|IDCD|IDH|IDP|IDPC|PICD;isocitrate dehydrogenase 1 (NADP+), soluble;IDH1;isocitrate dehydrogenase 1 (NADP+), soluble |
Definition | NADP(+)-specific ICDH|NADP-dependent isocitrate dehydrogenase, cytosolic|NADP-dependent isocitrate dehydrogenase, peroxisomal|epididymis luminal protein 216|epididymis secretory protein Li 26|isocitrate dehydrogenase [NADP] cytoplasmic|oxalosuccinate deca |
Position | 2q33.3 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 8718 |
TUSON P-value | 1 |
| Caution | This gene might be oncogene according to our integrated oncogene list. |
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Pathways and Diseases |
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Pathway | Citrate cycle (TCA cycle);KEGG PATHWAY;hsa00020 |
Pathway | respiration (anaerobic);BioCyc;ANARESP1-PWY |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Glutathione metabolism;KEGG PATHWAY;hsa00480 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Pathway | Peroxisome;KEGG PATHWAY;hsa04146 |
Pathway | NADPH regeneration;PID Reactome;500823 |
Disease | Cancer;FunDO |
Disease | Neoplasm metastasis;FunDO |
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External Links |
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Links to Entrez Gene | 3417 |
Links to all GeneRIF Items | 3417 |
Links to iHOP | 3417 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3417 : length: 1245 atgtccaaaaaaatcagtggcggttctgtggtagagatgcaaggagatgaaatgacacga atcatttgggaattgattaaagagaaactcatttttccctacgtggaattggatctacat agctatgatttaggcatagagaatcgtgatgccaccaacgaccaagtcaccaaggatgct gcagaagctataaagaagcataatgttggcgtcaaatgtgccactatcactcctgatgag aagagggttgaggagttcaagttgaaacaaatgtggaaatcaccaaatggcaccatacga aatattctgggtggcacggtcttcagagaagccattatctgcaaaaatatcccccggctt gtgagtggatgggtaaaacctatcatcataggtcgtcatgcttatggggatcaatacaga gcaactgattttgttgttcctgggcctggaaaagtagagataacctacacaccaagtgac ggaacccaaaaggtgacatacctggtacataactttgaagaaggtggtggtgttgccatg gggatgtataatcaagataagtcaattgaagattttgcacacagttccttccaaatggct ctgtctaagggttggcctttgtatctgagcaccaaaaacactattctgaagaaatatgat gggcgttttaaagacatctttcaggagatatatgacaagcagtacaagtcccagtttgaa gctcaaaagatctggtatgagcataggctcatcgacgacatggtggcccaagctatgaaa tcagagggaggcttcatctgggcctgtaaaaactatgatggtgacgtgcagtcggactct gtggcccaagggtatggctctctcggcatgatgaccagcgtgctggtttgtccagatggc aagacagtagaagcagaggctgcccacgggactgtaacccgtcactaccgcatgtaccag aaaggacaggagacgtccaccaatcccattgcttccatttttgcctggaccagagggtta gcccacagagcaaagcttgataacaataaagagcttgccttctttgcaaatgctttggaa gaagtctctattgagacaattgaggctggcttcatgaccaaggacttggctgcttgcatt aaaggtttacccaatgtgcaacgttctgactacttgaatacatttgagttcatggataaa cttggagaaaacttgaagatcaaactagctcaggccaaactttaa |
Protein Sequence |
>3417 : length: 414 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL |