| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 3483 |
Name | IGFALS |
Synonym | ACLSD|ALS;insulin-like growth factor binding protein, acid labile subunit;IGFALS;insulin-like growth factor binding protein, acid labile subunit |
Definition | insulin-like growth factor binding protein complex acid labile chain|insulin-like growth factor-binding protein complex acid labile subunit |
Position | 16p13.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 8802 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Diabetes pathways;Reactome;REACT:15380 |
Pathway | Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs);PID Reactome;500133 |
Disease | Amyotrophic lateral sclerosis;FunDO |
Disease | Breast cancer;FunDO |
Disease | Acid-labile subunit, deficiency of;OMIM |
Disease | Acromegaly;FunDO |
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External Links |
|
Links to Entrez Gene | 3483 |
Links to all GeneRIF Items | 3483 |
Links to iHOP | 3483 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3483 : length: 1932 atggccctgaggaaagcgggtgacctcgagcctcagttcacacctgagcgccgcttccgg ctgtgctggtatcaggctcactcgggcagagccctcctcgggccgcctccccaagcctct ccccccgcaggaggcctggccctggcgctgctgctgctgtcctgggtggcactgggcccc cgcagcctggagggagcagaccccggaacgccgggggaagccgagggcccagcgtgcccg gccgcctgtgtctgcagctacgatgacgacgcggatgagctcagcgtcttctgcagctcc aggaacctcacgcgcctgcctgatggagtcccgggcggcacccaagccctgtggctggac ggcaacaacctctcgtccgtccccccggcagccttccagaacctctccagcctgggcttc ctcaacctgcagggcggccagctgggcagcctggagccacaggcgctgctgggcctagag aacctgtgccacctgcacctggagcggaaccagctgcgcagcctggcactcggcacgttt gcacacacgcccgcgctggcctcgctcggcctcagcaacaaccgtctgagcaggctggag gacgggctcttcgagggcctcggcagcctctgggacctcaacctcggctggaatagcctg gcggtgctccccgatgcggcgttccgcggcctgggcagcctgcgcgagctggtgctggcg ggcaacaggctggcctacctgcagcccgcgctcttcagcggcctggccgagctccgggag ctggacctgagcaggaacgcgctgcgggccatcaaggcaaacgtgttcgtgcagctgccc cggctccagaaactctacctggaccgcaacctcatcgctgccgtggccccgggcgccttc ctgggcctgaaggcgctgcgatggctggacctgtcccacaaccgcgtggctggcctcctg gaggacacgttccccggtctgctgggcctgcgtgtgctgcggctgtcccacaacgccatc gccagcctgcggccccgcaccttcaaggacctgcacttcctggaggagctgcagctgggc cacaaccgcatccggcagctggctgagcgcagctttgagggcctggggcagcttgaggtg ctcacgctagaccacaaccagctccaggaggtcaaggcgggcgctttcctcggcctcacc aacgtggcggtcatgaacctctctgggaactgtctccggaaccttccggagcaggtgttc cggggcctgggcaagctgcacagcctgcacctggagggcagctgcctgggacgcatccgc ccgcacaccttcaccggcctctcggggctccgccgactcttcctcaaggacaacggcctc gtgggcattgaggagcagagcctgtgggggctggcggagctgctggagctcgacctgacc tccaaccagctcacgcacctgccccaccgcctcttccagggcctgggcaagctggagtac ctgctgctctcccgcaaccgcctggcagagctgccggcggacgccctgggccccctgcag cgggccttctggctggacgtctcgcacaaccgcctggaggcattgcccaacagcctcttg gcaccactggggcggctgcgctacctcagcctcaggaacaactcactgcggaccttcacg ccgcagcccccgggcctggagcgcctgtggctggagggtaacccctgggactgtggctgc cctctcaaggcgctgcgggacttcgccctgcagaaccccagtgctgtgccccgcttcgtc caggccatctgtgagggggacgattgccagccgcccgcgtacacctacaacaacatcacc tgtgccagcccgcccgaggtcgtggggctcgacctgcgggacctcagcgaggcccacttt gctccctgctga |
Protein Sequence |
>3483 : length: 643 MALRKAGDLEPQFTPERRFRLCWYQAHSGRALLGPPPQASPPAGGLALALLLLSWVALGP RSLEGADPGTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLD GNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTF AHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLA GNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAF LGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLG HNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVF RGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLT SNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLL APLGRLRYLSLRNNSLRTFTPQPPGLERLWLEGNPWDCGCPLKALRDFALQNPSAVPRFV QAICEGDDCQPPAYTYNNITCASPPEVVGLDLRDLSEAHFAPC |