| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3661 |
Name | IRF3 |
Synonym | -;interferon regulatory factor 3;IRF3;interferon regulatory factor 3 |
Definition | - |
Position | 19q13.3-q13.4 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 9027 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620 |
Pathway | RIG-I-like receptor signaling pathway;KEGG PATHWAY;hsa04622 |
Pathway | TRAM Cascade;PID Reactome;500465 |
Pathway | Cytosolic DNA-sensing pathway;KEGG PATHWAY;hsa04623 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | Toll receptor signaling pathway;PANTHER;P00054 |
Disease | esophageal cancer;GAD |
Disease | Infection;FunDO |
Disease | Rheumatoid arthritis;FunDO |
Disease | Lymphoma;FunDO |
Disease | CANCER;GAD |
Disease | cervical intraepithelial neoplasia grade 3;GAD |
Disease | Hemorrhagic fevers, Viral;FunDO |
Disease | Respiratory tract disease;FunDO |
|
External Links |
|
Links to Entrez Gene | 3661 |
Links to all GeneRIF Items | 3661 |
Links to iHOP | 3661 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3661 : length: 1359 atgggaaccccaaagccacggatcctgccctggctggtgtcgcagctggacctggggcaa ctggagggcgtggcctgggtgaacaagagccgcacgcgcttccgcatcccttggaagcac ggcctacggcaggatgcacagcaggaggatttcggaatcttccaggcctgggccgaggcc actggtgcatatgttcccgggagggataagccagacctgccaacctggaagaggaatttc cgctctgccctcaaccgcaaagaagggttgcgtttagcagaggaccggagcaaggaccct cacgacccacataaaatctacgagtttgtgaactcaggagttggggacttttcccagcca gacacctctccggacaccaatggtggaggcagtacttctgatacccaggaagacattctg gatgagttactgggtaacatggtgttggccccactcccagatccgggacccccaagcctg gctgtagcccctgagccctgccctcagcccctgcggagccccagcttggacaatcccact cccttcccaaacctggggccctctgagaacccactgaagcggctgttggtgccgggggaa gagtgggagttcgaggtgacagccttctaccggggccgccaagtcttccagcagaccatc tcctgcccggagggcctgcggctggtggggtccgaagtgggagacaggacgctgcctgga tggccagtcacactgccagaccctggcatgtccctgacagacaggggagtgatgagctac gtgaggcatgtgctgagctgcctgggtgggggactggctctctggcgggccgggcagtgg ctctgggcccagcggctggggcactgccacacatactgggcagtgagcgaggagctgctc cccaacagcgggcatgggcctgatggcgaggtccccaaggacaaggaaggaggcgtgttt gacctggggcccttcattgtaggctcctgggcccccagatctgattaccttcacggaagg aagcggacgctcaccacgctatgccctctggttctgtgtgggggagtcatggccccagga ccagccgtggaccaagaggctcgtgatggtcaaggttgtgcccacgtgcctcagggcctt ggtagaaatggcccgggtagggggtgcctcctccctggagaatactgtggacctgcacat ttccaacagccacccactctccctcacctccgaccagtacaaggcctacctgcaggactt ggtggagggcatggatttccagggccctggggagagctgagccctcgctcctcatggtgt gcctccaacccccctgttccccaccacctcaaccaataa |
Protein Sequence |
>3661 : length: 452 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL PNSGHGPDGEVPKDKEGGVFDLGPFIVGSWAPRSDYLHGRKRTLTTLCPLVLCGGVMAPG PAVDQEARDGQGCAHVPQGLGRNGPGRGCLLPGEYCGPAHFQQPPTLPHLRPVQGLPAGL GGGHGFPGPWGELSPRSSWCASNPPVPHHLNQ |