| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 383 |
Name | ARG1 |
Synonym | -;arginase 1;ARG1;arginase 1 |
Definition | arginase, liver|arginase-1|liver-type arginase|type I arginase |
Position | 6q23 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 2974 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Amoebiasis;KEGG PATHWAY;hsa05146 |
Pathway | superpathway of citrulline metabolism;BioCyc;PWY-5004 |
Pathway | Arginine and proline metabolism;KEGG PATHWAY;hsa00330 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Metabolism of amino acids and derivatives;Reactome;REACT:13 |
Pathway | arginine degradation I (arginase pathway);BioCyc;ARGASEDEG-PWY |
Pathway | ATF-2 transcription factor network;PID Curated;200116 |
Pathway | urea cycle;BioCyc;PWY-4984 |
Pathway | citrulline biosynthesis;BioCyc;CITRULBIO-PWY |
Pathway | Urea cycle;PID Reactome;500783 |
Pathway | arginine degradation VI (arginase 2 pathway);BioCyc;ARG-PRO-PWY |
Disease | Hepatitis, Autoimmune;FunDO |
Disease | IMMUNE;GAD |
Disease | Genetic disorders;KEGG DISEASE |
Disease | Inherited disorders of amino acid metabolism;KEGG DISEASE |
Disease | Hypertension;FunDO |
Disease | Hyperargininemia;KEGG DISEASE;H00186 |
Disease | CARDIOVASCULAR;GAD |
Disease | Asthma;FunDO |
Disease | bronchodilator response;GAD |
Disease | Liver metastases;FunDO |
Disease | Argininemia;OMIM |
Disease | Sickle cell disease;FunDO |
Disease | intima-media thickness myocardial infarct;GAD |
|
External Links |
|
Links to Entrez Gene | 383 |
Links to all GeneRIF Items | 383 |
Links to iHOP | 383 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>383 : length: 969 atgagcgccaagtccagaaccatagggattattggagctcctttctcaaagggacagcca cgaggaggggtggaagaaggccctacagtattgagaaaggctggtctgcttgagaaactt aaagaacaagagtgtgatgtgaaggattatggggacctgccctttgctgacatccctaat gacagtccctttcaaattgtgaagaatccaaggtctgtgggaaaagcaagcgagcagctg gctggcaaggtggcagaagtcaagaagaacggaagaatcagcctggtgctgggcggagac cacagtttggcaattggaagcatctctggccatgccagggtccaccctgatcttggagtc atctgggtggatgctcacactgatatcaacactccactgacaaccacaagtggaaacttg catggacaacctgtatctttcctcctgaaggaactaaaaggaaagattcccgatgtgcca ggattctcctgggtgactccctgtatatctgccaaggatattgtgtatattggcttgaga gacgtggaccctggggaacactacattttgaaaactctaggcattaaatacttttcaatg actgaagtggacagactaggaattggcaaggtgatggaagaaacactcagctatctacta ggaagaaagaaaaggccaattcatctaagttttgatgttgacggactggacccatctttc acaccagctactggcacaccagtcgtgggaggtctgacatacagagaaggtctctacatc acagaagaaatctacaaaacagggctactctcaggattagatataatggaagtgaaccca tccctggggaagacaccagaagaagtaactcgaacagtgaacacagcagttgcaataacc ttggcttgtttcggacttgctcgggagggtaatcacaagcctattgactaccttaaccca cctaagtaa |
Protein Sequence |
>383 : length: 322 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT LACFGLAREGNHKPIDYLNPPK |