| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3996 |
Name | LLGL1 |
Synonym | DLG4|HUGL|HUGL-1|HUGL1|LLGL;lethal giant larvae homolog 1 (Drosophila);LLGL1;lethal giant larvae homolog 1 (Drosophila) |
Definition | human homolog to the D-lgl gene protein|lethal(2) giant larvae protein homolog 1 |
Position | 17p11.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 9910 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Tight junction;KEGG PATHWAY;hsa04530 |
Disease | Metastasis to lymph nodes;FunDO |
Disease | Melanoma;FunDO |
Disease | Colon cancer;FunDO |
Disease | Endometrium cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 3996 |
Links to all GeneRIF Items | 3996 |
Links to iHOP | 3996 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3996 : length: 3195 atgatgaagtttcggttccggcggcagggcgccgacccgcagcgcgagaagctcaagcag gagcttttcgccttcaacaagactgtggagcatggcttccccaatcagcccagcgccctg gccttcgacccggaacttcgcatcatggccatcggcaccaggtctggggctgtcaagatc tatggtgcacctggcgtggagttcacaggcctgcaccgggatgcagccactgtcacacag atgcacttcttgaccggccagggccgcctcctgtccctgcttgatgacagcagtctgcat ctctgggagattgtccaccataatggctgtgcccacctggaagaagcactcagtttccag ctgcccagccggcccggctttgatggtgccagtgctccgctcagccttacccgagtcaca gtggtcctgctggtggctgccggcgacatagcagccctgggcactgagggcagcagtgtc ttcttcctggatgttaccaccctgaccctgctcgaggggcagacgcttgccccaggcgag gttctgcgcagcgtgccagacgactaccgctgtgggaaggcactgggccccgtggagtca ctccagggacacctgcgggaccccacaaagattctcattggctacagccggggcctgctg gtcatctggaaccaggcctcgcagtgtgtggaccacatcttcctggggaaccagcagctg gagagcctatgctgggggcgtgatagcagcactgtggtcagctcacacagcgatggcagc tatgctgtctggtctgtggatgccggcagcttcccaacgctgcagcccacggtagccacc acaccttacggcccctttccctgcaaggccattaacaagattctgtggcggaactgtgaa tctgggggccactttatcatcttcagcggtggcatgccccgtgccagctatggtgaccgc cactgtgtaagtgtgcttcgagccgagacattggtgacgctggacttcacttcccgcatc atcgacttcttcacagtgcacagcacacggcccgaggatgaatttgatgacccccaggcc ctggctgtgctgctggaagaggagctggtggtgctggacctgcagactcctggctggcca gctgtgcctgccccatacctggccccgctgcactcctctgcaatcacttgctcggcccac gtggccagtgtccccgccaagctgtgggcccgcattgtgagcgctggcgagcagcagagc ccccagcctgtctccagtgccttgagctggcccatcactgggggccgaaacctggcccag gagccgtcacagcgagggctgctgctgacgggccatgaggacggcaccgtgaggttctgg gatgcctcgggtgtggcgctgcggccgctctataagctgagcacagctggcctcttccag acagactgtgagcacgctgacagcctggcccaggctgccgaggacgactggccacccttc cgcaaggtgggctgcttcgatccctacagtgacgatccccggcttggcgtgcagaaggtt gctctctgcaagtatacagcccagatggtggtggctggcactgcaggccaggtgctggta ctggagcttagtgatgtgccggtggagcaggcggtcagcgtggccatcatagacctcctc caggaccgcgagggcttcacatggaagggccacgagcggctgagcccacgcacggggccg ctgccctggcctgctggcttccagccccgtgtcctggtgcagtgcctgccgccagctgct gtaaccgctgtcacactccacaccgagtggagcctcgtggcttttggcaccagtcatggc tttggcctcttcgactaccagcgcaagagccctgtgctggccaggtgcactcttcacccc aatgactccctggccatggagggtccgctctcccgggtgaagtctctcaagaagtcactg cgccagtctttccggcgcattcgcaagagtcgtgtctctggcaagaagcgggctgctaat gccagcagcaagttgcaggaagccaatgcacagctggctgagcaggcctgcccccacgac gtggagatgacgcccgtgcagcgccgcattgagccccgctctgccgatgactccttgtcg ggtgtcgtgcgttgcctatactttgccgacacattccttcgagatggggcccaccacggg cccaccatgtgggctggcaccaactcaggctctgtgttcgcctatgcactggaggtgccg gcagcagcagtgggtggtgagaagcggcctgagcaagcggtggaggccgtgctgggcaag gaggtgcagctgatgcaccgggcgcctgtggtggccattgccgtgttggacgggcgtggc cgcccactgcccgagccctacgaggcctcacgggacctggcgcaggcacctgacatgcag ggtggtcacgctgtgctcatcgcatctgaggagcagttcaaggtgttcacactgcccaag gtgagcgcgaagaccaagttcaagctgacggcccatgagggctgtcgtgtgcgcaaggtg gcactggccacgtttgccagtgtggcctgcgaggactatgctgagacctgcctggcctgc ctcaccaacctgggtgacgtccacgtcttctcggtgcctggcctgcggccccaggtgcac tattcctgcatccggaaggaggacatcagcggcatcgcttcgtgcgtctttacgcgccat ggccagggcttttacctgatatccccatcagaatttgaacgcttctccctaagtgcccgg aacatcacagagccgctctgctctctggacattaactggccccgcgatgccacccaggcc agttacaggatccgagagtcacccaagctgagccaggctaacgggaccccaagcatcctg ctggccccacagagccttgatggaagccctgatccagcccacagcatgggacctgacacc ccggagccacccgaggctgcactctcacccatgtccatcgactcagccaccagtgctgac accacgctggacacgacaggggacgtcacagtggaagatgtgaaggatttcctgggctcc tctgaggagtcagagaagaacctgaggaacctggcagaagacgaggcccacgcctgtgcc atcctgatcaaatga |
Protein Sequence |
>3996 : length: 1064 MMKFRFRRQGADPQREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKI YGAPGVEFTGLHRDAATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQ LPSRPGFDGASAPLSLTRVTVVLLVAAGDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGE VLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQL ESLCWGRDSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCE SGGHFIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQA LAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQS PQPVSSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQ TDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLV LELSDVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAA VTAVTLHTEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSL RQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLS GVVRCLYFADTFLRDGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGK EVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPK VSAKTKFKLTAHEGCRVRKVALATFASVACEDYAETCLACLTNLGDVHVFSVPGLRPQVH YSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDATQA SYRIRESPKLSQANGTPSILLAPQSLDGSPDPAHSMGPDTPEPPEAALSPMSIDSATSAD TTLDTTGDVTVEDVKDFLGSSEESEKNLRNLAEDEAHACAILIK |