| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 4144 |
Name | MAT2A |
Synonym | MATA2|MATII|SAMS2;methionine adenosyltransferase II, alpha;MAT2A;methionine adenosyltransferase II, alpha |
Definition | MAT 2|MAT-II|S-adenosylmethionine synthase isoform type-2|adoMet synthase 2|adoMet synthetase 2|methionine adenosyltransferase 2 |
Position | 2p11.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 10347 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | methionine degradation I (to homocysteine);BioCyc;METHIONINE-DEG1-PWY |
Pathway | S-adenosylmethionine biosynthesis;BioCyc;SAM-PWY |
Pathway | Selenoamino acid metabolism;KEGG PATHWAY;hsa00450 |
Pathway | cysteine biosynthesis III (mammalia);BioCyc;PWY-6292 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | S-adenosylmethionine biosynthesis;PANTHER;P02773 |
Pathway | Biological oxidations;Reactome;REACT:13433 |
Pathway | C-MYB transcription factor network;PID Curated;200130 |
Pathway | Cysteine and methionine metabolism;KEGG PATHWAY;hsa00270 |
Pathway | superpathway of methionine degradation;BioCyc;PWY-5328 |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 4144 |
Links to all GeneRIF Items | 4144 |
Links to iHOP | 4144 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>4144 : length: 1188 atgaacggacagctcaacggcttccacgaggcgttcatcgaggagggcacattccttttc acctcagagtcggtcggggaaggccacccagataagatttgtgaccaaatcagtgatgct gtccttgatgcccaccttcagcaggatcctgatgccaaagtagcttgtgaaactgttgct aaaactggaatgatccttcttgctggggaaattacatccagagctgctgttgactaccag aaagtggttcgtgaagctgttaaacacattggatatgatgattcttccaaaggttttgac tacaagacttgtaacgtgctggtagccttggagcaacagtcaccagatattgctcaaggt gttcatcttgacagaaatgaagaagacattggtgctggagaccagggcttaatgtttggc tatgccactgatgaaactgaggagtgtatgcctttaaccattgtcttggcacacaagcta aatgccaaactggcagaactacgccgtaatggcactttgccttggttacgccctgattct aaaactcaagttactgtgcagtatatgcaggatcgaggtgctgtgcttcccatcagagtc cacacaattgttatatctgttcagcatgatgaagaggtttgtcttgatgaaatgagggat gccctaaaggagaaagtcatcaaagcagttgtgcctgcgaaataccttgatgaggataca atctaccacctacagccaagtggcagatttgttattggtgggcctcagggtgatgctggt ttgactggacgcaaaatcattgtggacacttatggcggttggggtgctcatggaggaggt gccttttcaggaaaggattataccaaggtcgaccgttcagctgcttatgctgctcgttgg gtggcaaaatcccttgttaaaggaggtctgtgccggagggttcttgttcaggtctcttat gctattggagtttctcatccattatctatctccattttccattatggtacctctcagaag agtgagagagagctattagagattgtgaagaagaatttcgatctccgccctggggtcatt gtcagggatctggatctgaagaagccaatttatcagaggactgcagcctatggccacttt ggtagggacagcttcccatgggaagtgcccaaaaagcttaaatattga |
Protein Sequence |
>4144 : length: 395 MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY |