| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 43 |
Name | ACHE |
Synonym | ACEE|ARACHE|N-ACHE|YT;acetylcholinesterase (Yt blood group);ACHE;acetylcholinesterase (Yt blood group) |
Definition | Yt blood group|acetylcholinesterase|apoptosis-related acetylcholinesterase |
Position | 7q22 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 2307 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Nicotinic acetylcholine receptor signaling pathway;PANTHER;P00044 |
Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway;PANTHER;P00043 |
Pathway | Glycerophospholipid metabolism;KEGG PATHWAY;hsa00564 |
Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway;PANTHER;P00042 |
Pathway | Synaptic Transmission;Reactome;REACT:13685 |
Pathway | ATF-2 transcription factor network;PID Curated;200116 |
Pathway | Neurotransmitter Clearance In The Synaptic Cleft;PID Reactome;500154 |
Disease | paraoxonase;GAD |
Disease | Neurodegenerative disorder;FunDO |
Disease | Ovarian cancer;FunDO |
Disease | Lung cancer;FunDO |
Disease | Blood group, Yt system;OMIM |
Disease | Vitiligo;FunDO |
Disease | Brain tumor;FunDO |
Disease | acetylcholinesterase;GAD |
Disease | acute sensitivity to anti-acetylcholinesterases;GAD |
Disease | Colon cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 43 |
Links to all GeneRIF Items | 43 |
Links to iHOP | 43 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>43 : length: 1845 atgaggcccccgcagtgtctgctgcacacgccttccctggcttccccactccttctcctc ctcctctggctcctgggtggaggagtgggggctgagggccgggaggatgcagagctgctg gtgacggtgcgtgggggccggctgcggggcattcgcctgaagacccccgggggccctgtc tctgctttcctgggcatcccctttgcggagccacccatgggaccccgtcgctttctgcca ccggagcccaagcagccttggtcaggggtggtagacgctacaaccttccagagtgtctgc taccaatatgtggacaccctatacccaggttttgagggcaccgagatgtggaaccccaac cgtgagctgagcgaggactgcctgtacctcaacgtgtggacaccatacccccggcctaca tcccccacccctgtcctcgtctggatctatgggggtggcttctacagtggggcctcctcc ttggacgtgtacgatggccgcttcttggtacaggccgagaggactgtgctggtgtccatg aactaccgggtgggagcctttggcttcctggccctgccggggagccgagaggccccgggc aatgtgggtctcctggatcagaggctggccctgcagtgggtgcaggagaacgtggcagcc ttcgggggtgacccgacatcagtgacgctgtttggggagagcgcgggagccgcctcggtg ggcatgcacctgctgtccccgcccagccggggcctgttccacagggccgtgctgcagagc ggtgcccccaatggaccctgggccacggtgggcatgggagaggcccgtcgcagggccacg cagctggcccaccttgtgggctgtcctccaggcggcactggtgggaatgacacagagctg gtagcctgccttcggacacgaccagcgcaggtcctggtgaaccacgaatggcacgtgctg cctcaagaaagcgtcttccggttctccttcgtgcctgtggtagatggagacttcctcagt gacaccccagaggccctcatcaacgcgggagacttccacggcctgcaggtgctggtgggt gtggtgaaggatgagggctcgtattttctggtttacggggccccaggcttcagcaaagac aacgagtctctcatcagccgggccgagttcctggccggggtgcgggtcggggttccccag gtaagtgacctggcagccgaggctgtggtcctgcattacacagactggctgcatcccgag gacccggcacgcctgagggaggccctgagcgatgtggtgggcgaccacaatgtcgtgtgc cccgtggcccagctggctgggcgactggctgcccagggtgcccgggtctacgcctacgtc tttgaacaccgtgcttccacgctctcctggcccctgtggatgggggtgccccacggctac gagatcgagttcatctttgggatccccctggacccctctcgaaactacacggcagaggag aaaatcttcgcccagcgactgatgcgatactgggccaactttgcccgcacaggggatccc aatgagccccgagaccccaaggccccacaatggcccccgtacacggcgggggctcagcag tacgttagtctggacctgcggccgctggaggtgcggcgggggctgcgcgcccaggcctgc gccttctggaaccgcttcctccccaaattgctcagcgccaccgacacgctcgacgaggcg gagcgccagtggaaggccgagttccaccgctggagctcctacatggtgcactggaagaac cagttcgaccactacagcaagcaggatcgctgctcagacctgtga |
Protein Sequence |
>43 : length: 614 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN QFDHYSKQDRCSDL |