| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 4311 |
Name | MME |
Synonym | CALLA|CD10|NEP|SFE;membrane metallo-endopeptidase;MME;membrane metallo-endopeptidase |
Definition | atriopeptidase|common acute lymphocytic leukemia antigen|enkephalinase|membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)|membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)|membrane metallo-endopeptidase |
Position | 3q25.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 10632 |
TUSON P-value | 1 |
|
Pathways and Diseases |
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Pathway | Hematopoietic cell lineage;KEGG PATHWAY;hsa04640 |
Pathway | Alzheimer's disease;KEGG PATHWAY;hsa05010 |
Pathway | Protein digestion and absorption;KEGG PATHWAY;hsa04974 |
Pathway | Renin-angiotensin system;KEGG PATHWAY;hsa04614 |
Disease | PSYCH;GAD |
Disease | Diabetes mellitus;FunDO |
Disease | Abortion;FunDO |
Disease | Acne;FunDO |
Disease | Alzheimer's disease;GAD |
Disease | Amyloidosis;FunDO |
Disease | anxiety;GAD |
Disease | Cancer;FunDO |
Disease | Membranous glomerulonephritis, antenatal;OMIM |
Disease | cerebral amyloid angiopathy.;GAD |
Disease | Neutral endopeptidase deficiency;OMIM |
Disease | Kidney disease;FunDO |
Disease | HIV infection;FunDO |
Disease | Alzheimer's disease;FunDO |
Disease | low amplitude P300 waves;GAD |
Disease | NEUROLOGICAL;GAD |
Disease | Cholestasis;FunDO |
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External Links |
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Links to Entrez Gene | 4311 |
Links to all GeneRIF Items | 4311 |
Links to iHOP | 4311 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>4311 : length: 2253 atgggcaagtcagaaagtcagatggatataactgatatcaacactccaaagccaaagaag aaacagcgatggactccactggagatcagcctctcggtccttgtcctgctcctcaccatc atagctgtgacaatgatcgcactctatgcaacctacgatgatggtatttgcaagtcatca gactgcataaaatcagctgctcgactgatccaaaacatggatgccaccactgagccttgt acagactttttcaaatatgcttgcggaggctggttgaaacgtaatgtcattcccgagacc agctcccgttacggcaactttgacattttaagagatgaactagaagtcgttttgaaagat gtccttcaagaacccaaaactgaagatatagtagcagtgcagaaagcaaaagcattgtac aggtcttgtataaatgaatctgctattgatagcagaggtggagaacctctactcaaactg ttaccagacatatatgggtggccagtagcaacagaaaactgggagcaaaaatatggtgct tcttggacagctgaaaaagctattgcacaactgaattctaaatatgggaaaaaagtcctt attaatttgtttgttggcactgatgataagaattctgtgaatcatgtaattcatattgac caacctcgacttggcctcccttctagagattactatgaatgcactggaatctataaagag gcttgtacagcatatgtggattttatgatttctgtggccagattgattcgtcaggaagaa agattgcccatcgatgaaaaccagcttgctttggaaatgaataaagttatggaattggaa aaagaaattgccaatgctacggctaaacctgaagatcgaaatgatccaatgcttctgtat aacaagatgacattggcccagatccaaaataacttttcactagagatcaatgggaagcca ttcagctggttgaatttcacaaatgaaatcatgtcaactgtgaatattagtattacaaat gaggaagatgtggttgtttatgctccagaatatttaaccaaacttaagcccattcttacc aaatattctgccagagatcttcaaaatttaatgtcctggagattcataatggatcttgta agcagcctcagccgaacctacaaggagtccagaaatgctttccgcaaggccctttatggt acaacctcagaaacagcaacttggagacgttgtgcaaactatgtcaatgggaatatggaa aatgctgtggggaggctttatgtggaagcagcatttgctggagagagtaaacatgtggtc gaggatttgattgcacagatccgagaagtttttattcagactttagatgacctcacttgg atggatgccgagacaaaaaagagagctgaagaaaaggccttagcaattaaagaaaggatc ggctatcctgatgacattgtttcaaatgataacaaactgaataatgagtacctcgagttg aactacaaagaagatgaatacttcgagaacataattcaaaatttgaaattcagccaaagt aaacaactgaagaagctccgagaaaaggtggacaaagatgagtggataagtggagcagct gtagtcaatgcattttactcttcaggaagaaatcagatagtcttcccagccggcattctg cagccccccttctttagtgcccagcagtccaactcattgaactatgggggcatcggcatg gtcataggacacgaaatcacccatggcttcgatgacaatggcagaaactttaacaaagat ggagacctcgttgactggtggactcaacagtctgcaagtaactttaaggagcaatcccag tgcatggtgtatcagtatggaaacttttcctgggacctggcaggtggacagcaccttaat ggaattaatacactgggagaaaacattgctgataatggaggtcttggtcaagcatacaga gcctatcagaattatattaaaaagaatggcgaagaaaaattacttcctggacttgaccta aatcacaaacaactatttttcttgaactttgcacaggtgtggtgtggaacctataggcca gagtatgcggttaactccattaaaacagatgtgcacagtccaggcaatttcaggattatt gggactttgcagaactctgcagagttttcagaagcctttcactgccgcaagaattcatac atgaatccagaaaagaagtgccgggtttggtga |
Protein Sequence |
>4311 : length: 750 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW |