| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 445 |
Name | ASS1 |
Synonym | ASS|CTLN1;argininosuccinate synthase 1;ASS1;argininosuccinate synthase 1 |
Definition | argininosuccinate synthase|argininosuccinate synthetase 1|citrulline--aspartate ligase|citrulline-aspartate ligase |
Position | 9q34.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 3164 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | superpathway of citrulline metabolism;BioCyc;PWY-5004 |
Pathway | Alanine, aspartate and glutamate metabolism;KEGG PATHWAY;hsa00250 |
Pathway | Arginine biosynthesis;PANTHER;P02728 |
Pathway | arginine biosynthesis IV;BioCyc;ARGININE-SYN4-PWY |
Pathway | Arginine and proline metabolism;KEGG PATHWAY;hsa00330 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Metabolism of amino acids and derivatives;Reactome;REACT:13 |
Pathway | urea cycle;BioCyc;PWY-4984 |
Pathway | citrulline-nitric oxide cycle;BioCyc;PWY-4983 |
Disease | Renal Cell cancer;FunDO |
Disease | Embryoma;FunDO |
Disease | Encephalopathies;FunDO |
Disease | Genetic disorders;KEGG DISEASE |
Disease | Inherited disorders of amino acid metabolism;KEGG DISEASE |
Disease | Citrullinemia;OMIM |
Disease | Citrullinemia;KEGG DISEASE;H00185 |
|
External Links |
|
Links to Entrez Gene | 445 |
Links to all GeneRIF Items | 445 |
Links to iHOP | 445 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>445 : length: 1239 atgtccagcaaaggctccgtggttctggcctacagtggcggcctggacacctcgtgcatc ctcgtgtggctgaaggaacaaggctatgacgtcattgcctatctggccaacattggccag aaggaagacttcgaggaagccaggaagaaggcactgaagcttggggccaaaaaggtgttc attgaggatgtcagcagggagtttgtggaggagttcatctggccggccatccagtccagc gcactgtatgaggaccgctacctcctgggcacctctcttgccaggccctgcatcgcccgc aaacaagtggaaatcgcccagcgggagggggccaagtatgtgtcccacggcgccacagga aaggggaacgatcaggtccggtttgagctcagctgctactcactggccccccagataaag gtcattgctccctggaggatgcctgaattctacaaccggttcaagggccgcaatgacctg atggagtacgcaaagcaacacgggattcccatcccggtcactcccaagaacccgtggagc atggatgagaacctcatgcacatcagctacgaggctggaatcctggagaaccccaagaac caagcgcctccaggtctctacacgaagacccaggacccagccaaagcccccaacacccct gacattctcgagatcgagttcaaaaaaggggtccctgtgaaggtgaccaacgtcaaggat ggcaccacccaccagacctccttggagctcttcatgtacctgaacgaagtcgcgggcaag catggcgtgggccgtattgacatcgtggagaaccgcttcattggaatgaagtcccgaggt atctacgagaccccagcaggcaccatcctttaccatgctcatttagacatcgaggccttc accatggaccgggaagtgcgcaaaatcaaacaaggcctgggcttgaaatttgctgagctg gtgtataccggtttctggcacagccctgagtgtgaatttgtccgccactgcatcgccaag tcccaggagcgagtggaagggaaagtgcaggtgtccgtcctcaagggccaggtgtacatc ctcggccgggagtccccactgtctctctacaatgaggagctggtgagcatgaacgtgcag ggtgattatgagccaactgatgccaccgggttcatcaacatcaattccctcaggctgaag gaatatcatcgtctccagagcaaggtcactgccaaatag |
Protein Sequence |
>445 : length: 412 MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK |