Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

463

Name

ZFHX3

Synonym

ATBF1|ATBT|ZNF927;zinc finger homeobox 3;ZFHX3;zinc finger homeobox 3

Definition

AT motif-binding factor 1|AT-binding transcription factor 1|ZFH-3|alpha-fetoprotein enhancer binding protein|alpha-fetoprotein enhancer-binding protein|zinc finger homeobox protein 3|zinc finger homeodomain protein 3

Position

16q22.3

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

344

TUSON P-value

0.00402927

Pathways and Diseases

Pathway

extrinsic prothrombin activation pathway;PID BioCarta;100168

Pathway

fibrinolysis pathway;PID BioCarta;100164

Pathway

intrinsic prothrombin activation pathway;PID BioCarta;100122

Pathway

C-MYB transcription factor network;PID Curated;200130

Disease

kawasaki disease;GAD

Disease

Atrial Fibrillation;GAD

Disease

Prostate cancer;FunDO

Disease

Metastasis to lymph nodes;FunDO

Disease

IMMUNE;GAD

Disease

Multiple malignancy;FunDO

Disease

CARDIOVASCULAR;GAD

Disease

Prostate cancer, susceptibility to;OMIM

Disease

Breast cancer;FunDO

Disease

Stomach cancer;FunDO

Disease

Liver cancer;FunDO

Disease

Kawasaki disease;NHGRI

Disease

Atrial fibrillation;NHGRI

External Links

Links to Entrez Gene

463

Links to all GeneRIF Items

463

Links to iHOP

463

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>463 : length: 8370
atgcggctcgggggcgggcagctggtgtcagaggagctgatgaacctgggcgagagcttc
atccagaccaacgacccgtcgctgaagctcttccagtgcgccgtctgcaacaagttcacg
acggacaacctggacatgctgggcctgcacatgaacgtggagcgcagcctgtcggaggac
gagtggaaggcggtgatgggggactcataccagtgcaagctctgccgctacaacacccag
ctcaaggccaacttccagctgcactgcaagacagacaagcacgtgcagaagtaccagctg
gtggcccacatcaaggagggcggcaaggccaacgagtggaggctcaagtgtgtggccatc
ggcaaccccgtgcacctcaagtgcaacgcctgtgactactacaccaacagcctggagaag
ctgcggctgcacacggtcaactccaggcacgaggccagcctgaagttgtacaagcacctg
cagcagcatgagagtggtgtagaaggtgagagctgctactaccactgcgttctgtgcaac
tactccaccaaggccaagctcaacctcatccagcatgtgcgctccatgaagcaccagcga
agcgagagcctgcgaaagctgcagcggctgcagaagggccttccagaggaggacgaggac
ctggggcagatcttcaccatccgcaggtgcccctccacggacccagaagaagccattgaa
gatgttgaaggacccagtgaaacagctgctgatccagaggagcttgctaaggaccaagag
ggcggagcatcgtccagccaagcagagaaggagctgacagattctcctgcaacctccaaa
cgcatctccttcccaggtagctcagagtctcccctctcttcgaagcgaccaaaaacagct
gaggagatcaaaccggagcagatgtaccagtgtccctactgcaagtacagtaatgccgat
gtcaaccggctccgggtgcatgccatgacgcagcactcggtgcaacccatgcttcgctgc
cccctgtgccaggacatgctcaacaacaagatccacctccagctgcacctcacccacctc
cacagcgtggcacctgactgcgtggagaagctcattatgacggtgaccacccctgagatg
gtgatgccaagcagcatgttcctcccagcagctgttccagatcgagatgggaattccaat
ttggaagaggcaggaaagcagcctgaaacctcagaggatctgggaaagaacatcttgcca
tccgcaagcacagagcaaagcggagatttgaaaccatcccctgctgacccaggctctgtg
agagaagactcaggcttcatctgctggaagaaggggtgcaaccaggttttcaaaacttct
gctgcccttcagacgcattttaatgaagtgcatgccaagaggcctcagctgccggtgtca
gatcgccatgtgtacaagtaccgctgtaatcagtgtagcctggccttcaagaccattgaa
aagttgcagctccattctcagtaccatgtgatcagagctgccaccatgtgctgtctttgt
cagcgcagtttccgaactttccaggctctgaagaagcaccttgagacaagccacctggag
ctgagtgaggctgacatccaacagctttatggtggcctgctggccaatggggacctcctg
gcaatgggagaccccactctggcagaggaccataccataattgttgaggaagacaaggag
gaagagagtgacttggaagataaacagagcccaacgggcagtgactctgggtcagtacaa
gaagactcgggctcagagccaaagagagctctgcctttcagaaaaggtcccaattttact
atggaaaagttcctagacccttctcgcccttacaagtgtaccgtctgcaaggaatctttc
actcaaaagaatatcctgctagtacactacaattctgtctcccacctgcataagttaaag
agagcccttcaagaatcagcaaccggtcagccagaacccaccagcagcccagacaacaaa
ccttttaagtgtaacacttgtaatgtggcctacagccagagttccactctggagatccat
atgaggtctgtgttacatcaaaccaaggcccgggcagccaagctggaggctgcaagtggc
agcagcaatgggactgggaacagcagcagtatttccttgagctcctccacgccaagtcct
gtgagcaccagtggcagtaacacctttaccacctccaatccaagcagtgctggcattgct
ccaagctctaacttactaagccaagtgcccactgagagtgtagggatgccacccctgggg
aatcctattggtgccaacattgcttccccttcagagcccaaagaggccaatcggaagaaa
ctggcagatatgattgcatccaggcagcagcaacaacagcagcagcaacagcaacaacaa
caacaacaacaacaacaacaagcacaaacgctggcccaggcccaggctcaagttcaagct
cacctgcagcaggagctgcagcaacaggctgccctgatccagtctcagctgtttaacccc
accctccttcctcacttccccatgacaactgagaccctgctgcaactacagcagcagcag
cacctcctcttccctttctacatccccagtgctgagttccagcttaaccccgaggtgagc
ttgccagtgaccagtggggcactgacactgactgggacaggcccaggcctgctggaagat
ctgaaggctcaggttcaggtcccacagcagagccatcagcagatcttgccgcagcagcag
cagaaccaactctctatagcccagagtcactctgccctccttcagccaagccagcacccc
gaaaagaagaacaaattggtcatcaaagaaaaggaaaaagaaagccagagagagagggac
agcgccgaggggggagagggcaacaccggtccgaaggaaacactgccagatgccttgaag
gccaaagagaagaaagagttggcaccagggggtggttctgagccttccatgctccctcca
cgcattgcttcagatgccagagggaacgccaccaaggccctgctggagaactttggcttt
gagttggtcatccagtataatgagaacaagcagaaggtgcagaaaaagaatgggaagact
gaccagggagagaacctggaaaagctcgagtgtgactcctgcggcaagttgttttccaac
atcttgattttaaagagtcatcaagagcacgttcatcagaattactttcctttcaaacag
ctcgagaggtttgccaaacagtacagagaccactacgataaactgtacccactgaggccc
cagaccccagagccaccaccacctccccctccaccccctccacccccacttccggcagcg
ccgcctcagccggcgtccacaccagccatccccgcatcagccccacccatcacctcacct
acaattgcaccggcccagccatcagtgccgctcacccagctctccatgccgatggagctg
cccatcttctcgccgctgatgatgcagacgatgccgctgcagaccttgccggctcagcta
cccccgcagctgggacctgtggagcctctgcctgcggacctggcccaactctaccagcat
cagctcaatccaaccctgctccagcagcagaacaagaggcctcgcaccaggatcacagat
gatcagctccgagtcttgcggcaatattttgacattaacaactcccccagtgaagagcaa
ataaaagagatggcagacaagtccgggttgccccagaaagtgatcaagcactggttcagg
aacactctcttcaaagagaggcagcgtaacaaggactccccttacaacttcagtaatcct
cctatcaccagcctggaggagctcaagattgactcccggcccccttcgccggaacctcca
aagcaggagtactggggaagcaagaggtcttcaagaacaaggtttacggactaccagctg
agggtcttacaggacttcttcgatgccaatgcttacccaaaggatgatgaatttgagcaa
ctctctaatttactgaaccttccaacccgagtgatagtggtgtggtttcagaatgcccga
cagaaggccaggaagaattatgagaatcagggagagggcaaagatggagagcggcgtgag
cttacaaatgatagatacattcgaacaagcaacttgaactaccagtgcaaaaaatgtagc
ctggtgtttcagcgcatctttgatctcatcaagcaccagaagaagctgtgttacaaggat
gaggatgaggaggggcaggacgacagccaaaatgaggattccatggatgccatggaaatc
ctgacgcctaccagctcatcctgcagtaccccgatgccctcacaggcttacagcgcccca
gcaccatcagccaataatacagcttcctccgctttcttgcagcttacagcggaggctgag
gaactggccaccttcaattcaaaaacagaggcaggcgatgagaaaccaaagctggcggaa
gctcccagtgcacagccaaaccaaacccaagaaaagcaaggacaaccaaagccagagctg
cagcagcaagagcagcccgagcagaagaccaacactccccagcagaagctcccccagctg
gtgtccctgccttcgttgccacagcctcctccacaagcgccccctccacagtgcccctta
ccccagtcgagccccagtccttcccagctctcccacctgcccctcaagcccctccacaca
tcaactcctcaacagctcgcaaacctacctcctcagctaatcccctaccagtgtgaccag
tgtaagttggcatttccgtcatttgagcactggcaggagcatcagcagctccacttcctg
agcgcgcagaaccagttcatccacccccagtttttggacaggtccctggatatgcctttc
atgctctttgatcccagtaacccactcctggccagccagctgctctctggggccatacct
cagattccagcaagctcagccacttctccttcaactccaacctccacaatgaacactctc
aagaggaagctggaggaaaaggccagtgcaagccctggcgaaaacgacagtgggacagga
ggagaagagcctcagagagacaagcgtttgagaacaaccatcacaccggaacaactagaa
attctctaccagaagtatctactggattccaatccgactcgaaagatgttggatcacatt
gcacacgaggtgggcttgaagaaacgtgtggtacaagtctggtttcagaacacccgagct
cgggaaaggaaaggacagttccgggctgtaggcccagcgcaggcccacaggagatgccct
ttttgcagagcgctcttcaaagccaagactgctcttgaggctcatatccggtcccgtcac
tggcatgaagccaagagagctggctacaacctaactctgtctgcgatgctcttagactgt
gatgggggactccagatgaaaggagatatttttgacggaactagcttttcccacctaccc
ccaagcagtagtgatggtcagggtgtccccctctcacctgtgagtaaaaccatggaattg
tcacccagaactcttctaagcccttcctccattaaggtggaagggattgaagactttgaa
agcccctccatgtcctcagttaatctaaactttgaccaaactaagctggacaacgatgac
tgttcctctgtcaacacagcaatcacagataccacaactggagacgagggcaacgcagat
aacgacagtgcaacgggaatagcaactgaaaccaaatcctcttctgcacccaacgaaggg
ttgaccaaagcggccatgatggcaatgtctgagtatgaagatcggttgtcatctggtctg
gtcagcccggccccgagcttttatagcaaggaatatgacaatgaaggtacagtggactac
agtgaaacctcaagccttgcagatccctgctccccgagtcctggtgcgagtggatctgca
ggcaaatctggtgacagcggagatcggcctgggcagaaacgttttcgcactcaaatgacc
aatctgcagctgaaggtcctcaagtcatgctttaatgactacaggacacccactatgcta
gaatgtgaggtcctgggcaatgacattggactgccaaagagagtcgttcaggtctggttc
cagaatgcccgggcaaaagaaaagaagtccaagttaagcatggccaagcattttggtata
aaccaaacgagttatgagggacccaaaacagagtgcactttgtgtggcatcaagtacagc
gctcggctgtctgtacgtgaccatatcttttcccaacagcatatctccaaagttaaagac
accattggaagccagctggacaaggagaaagaatactttgacccagccaccgtacgtcag
ttgatggctcaacaagagttggaccggattaaaaaggccaacgaggtccttggactggca
gctcagcagcaagggatgtttgacaacacccctcttcaggcccttaaccttcctacagca
tatccagcgctccagggcattcctcctgtgttgctcccgggcctcaacagcccctccttg
ccaggctttactccatccaacacagctttaacgtctcctaagccgaacttgatgggtctg
cccagcacaactgttccttcccctggcctccccacttctggattaccaaataaaccgtcc
tcagcgtcgctgagctccccaaccccagcacaagccacgatggcgatgggccctcagcaa
cccccccagcagcagcagcagcagcagcaaccacaggtgcagcagcctcccccgccgcca
gcagcccagccgccacccacaccacagctcccactgcaacagcagcagcaacgcaaggac
aaagacagtgagaaagtaaaggagaaggaaaaggcacacaaagggaaaggggaacccctg
cctgtccccaagaaggagaaaggagaggcccccacggcaactgcagccacgatctcagcc
ccgctgcccaccatggagtatgcggtagaccctgcacagctgcaggccctgcaggccgcg
ttgacttcggaccccacagcattgctcacaagccagttccttccttactttgtaccaggc
ttttctccttattatgctccccagatccctggcgccctgcagagcgggtacctgcagcct
atgtatggcatggaaggcctgttcccctacagccctgcactgtcgcaggccctgatgggg
ctgtccccaggctccctactgcagcagtaccagcaataccagcagagtctgcaggaggca
attcagcagcagcagcagcggcaactacagcagcagcagcagcaaaaagtgcagcagcag
cagcccaaagcaagccaaaccccagtcccccccggggctccttccccagacaaagaccct
gccaaagaatcccccaaaccagaagaacagaaaaacaccccccgtgaggtgtcccccctc
ctgccgaaactccctgaagagccagaagcagaaagcaaaagtgcggactccctctacgac
cccttcattgttccaaaggtgcagtacaagttggtctgccgcaagtgccaggcgggcttc
agcgacgaggaggcagcgaggagccacctgaagtccctctgcttcttcggccagtctgtg
gtgaacctgcaagagatggtgcttcacgtccccaccggcggcggcggcggtggcagtggc
ggcggcggcggcggtggcggcggcggcggcggcggcggctcgtaccactgcctggcgtgc
gagagcgcgctctgtggggaggaagctctgagtcaacatctcgagtcggccttgcacaaa
cacagaacaatcacgagagcagcaagaaacgccaaagagcaccctagtttattacctcac
tctgcctgcttccccgatcctagcaccgcatctacctcgcagtctgccgctcactcaaac
gacagcccccctcccccgtcggccgccgccccctcctccgcttccccccacgcctccagg
aagtcttggccgcaagtggtctcccgggcttcggcagcgaagcccccttcttttcctcct
ctctcctcatcttcaacggttacctcaagttcatgcagcacctcaggggttcagccctcg
atgccaacagacgactattcggaggagtctgacacggatctcagccaaaagtccgacgga
ccggcgagcccggtggagggtcccaaagaccccagctgccccaaggacagtggtctgacc
agtgtaggaacggacaccttcagattgtaa

Protein Sequence

>463 : length: 2789
MRLGGGQLVSEELMNLGESFIQTNDPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSED
EWKAVMGDSYQCKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAI
GNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCN
YSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIE
DVEGPSETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISFPGSSESPLSSKRPKTA
EEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHL
HSVAPDCVEKLIMTVTTPEMVMPSSMFLPAAVPDRDGNSNLEEAGKQPETSEDLGKNILP
SASTEQSGDLKPSPADPGSVREDSGFICWKKGCNQVFKTSAALQTHFNEVHAKRPQLPVS
DRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRTFQALKKHLETSHLE
LSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKEEESDLEDKQSPTGSDSGSVQ
EDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLK
RALQESATGQPEPTSSPDNKPFKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAASG
SSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVGMPPLG
NPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQA
HLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVS
LPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQHP
EKKNKLVIKEKEKESQRERDSAEGGEGNTGPKETLPDALKAKEKKELAPGGGSEPSMLPP
RIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGENLEKLECDSCGKLFSN
ILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAA
PPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQL
PPQLGPVEPLPADLAQLYQHQLNPTLLQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQ
IKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLEELKIDSRPPSPEPP
KQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNAR
QKARKNYENQGEGKDGERRELTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKD
EDEEGQDDSQNEDSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAE
ELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQL
VSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQ
CKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIP
QIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQLE
ILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGPAQAHRRCP
FCRALFKAKTALEAHIRSRHWHEAKRAGYNLTLSAMLLDCDGGLQMKGDIFDGTSFSHLP
PSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFESPSMSSVNLNFDQTKLDNDD
CSSVNTAITDTTTGDEGNADNDSATGIATETKSSSAPNEGLTKAAMMAMSEYEDRLSSGL
VSPAPSFYSKEYDNEGTVDYSETSSLADPCSPSPGASGSAGKSGDSGDRPGQKRFRTQMT
NLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKSKLSMAKHFGI
NQTSYEGPKTECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQ
LMAQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSL
PGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQ
PPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPL
PVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPG
FSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEA
IQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREVSPL
LPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSV
VNLQEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHK
HRTITRAARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSPPPPSAAAPSSASPHASR
KSWPQVVSRASAAKPPSFPPLSSSSTVTSSSCSTSGVQPSMPTDDYSEESDTDLSQKSDG
PASPVEGPKDPSCPKDSGLTSVGTDTFRL



')