| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 463 |
Name | ZFHX3 |
Synonym | ATBF1|ATBT|ZNF927;zinc finger homeobox 3;ZFHX3;zinc finger homeobox 3 |
Definition | AT motif-binding factor 1|AT-binding transcription factor 1|ZFH-3|alpha-fetoprotein enhancer binding protein|alpha-fetoprotein enhancer-binding protein|zinc finger homeobox protein 3|zinc finger homeodomain protein 3 |
Position | 16q22.3 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 344 |
TUSON P-value | 0.00402927 |
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Pathways and Diseases |
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Pathway | extrinsic prothrombin activation pathway;PID BioCarta;100168 |
Pathway | fibrinolysis pathway;PID BioCarta;100164 |
Pathway | intrinsic prothrombin activation pathway;PID BioCarta;100122 |
Pathway | C-MYB transcription factor network;PID Curated;200130 |
Disease | kawasaki disease;GAD |
Disease | Atrial Fibrillation;GAD |
Disease | Prostate cancer;FunDO |
Disease | Metastasis to lymph nodes;FunDO |
Disease | IMMUNE;GAD |
Disease | Multiple malignancy;FunDO |
Disease | CARDIOVASCULAR;GAD |
Disease | Prostate cancer, susceptibility to;OMIM |
Disease | Breast cancer;FunDO |
Disease | Stomach cancer;FunDO |
Disease | Liver cancer;FunDO |
Disease | Kawasaki disease;NHGRI |
Disease | Atrial fibrillation;NHGRI |
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External Links |
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Links to Entrez Gene | 463 |
Links to all GeneRIF Items | 463 |
Links to iHOP | 463 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>463 : length: 8370 atgcggctcgggggcgggcagctggtgtcagaggagctgatgaacctgggcgagagcttc atccagaccaacgacccgtcgctgaagctcttccagtgcgccgtctgcaacaagttcacg acggacaacctggacatgctgggcctgcacatgaacgtggagcgcagcctgtcggaggac gagtggaaggcggtgatgggggactcataccagtgcaagctctgccgctacaacacccag ctcaaggccaacttccagctgcactgcaagacagacaagcacgtgcagaagtaccagctg gtggcccacatcaaggagggcggcaaggccaacgagtggaggctcaagtgtgtggccatc ggcaaccccgtgcacctcaagtgcaacgcctgtgactactacaccaacagcctggagaag ctgcggctgcacacggtcaactccaggcacgaggccagcctgaagttgtacaagcacctg cagcagcatgagagtggtgtagaaggtgagagctgctactaccactgcgttctgtgcaac tactccaccaaggccaagctcaacctcatccagcatgtgcgctccatgaagcaccagcga agcgagagcctgcgaaagctgcagcggctgcagaagggccttccagaggaggacgaggac ctggggcagatcttcaccatccgcaggtgcccctccacggacccagaagaagccattgaa gatgttgaaggacccagtgaaacagctgctgatccagaggagcttgctaaggaccaagag ggcggagcatcgtccagccaagcagagaaggagctgacagattctcctgcaacctccaaa cgcatctccttcccaggtagctcagagtctcccctctcttcgaagcgaccaaaaacagct gaggagatcaaaccggagcagatgtaccagtgtccctactgcaagtacagtaatgccgat gtcaaccggctccgggtgcatgccatgacgcagcactcggtgcaacccatgcttcgctgc cccctgtgccaggacatgctcaacaacaagatccacctccagctgcacctcacccacctc cacagcgtggcacctgactgcgtggagaagctcattatgacggtgaccacccctgagatg gtgatgccaagcagcatgttcctcccagcagctgttccagatcgagatgggaattccaat ttggaagaggcaggaaagcagcctgaaacctcagaggatctgggaaagaacatcttgcca tccgcaagcacagagcaaagcggagatttgaaaccatcccctgctgacccaggctctgtg agagaagactcaggcttcatctgctggaagaaggggtgcaaccaggttttcaaaacttct gctgcccttcagacgcattttaatgaagtgcatgccaagaggcctcagctgccggtgtca gatcgccatgtgtacaagtaccgctgtaatcagtgtagcctggccttcaagaccattgaa aagttgcagctccattctcagtaccatgtgatcagagctgccaccatgtgctgtctttgt cagcgcagtttccgaactttccaggctctgaagaagcaccttgagacaagccacctggag ctgagtgaggctgacatccaacagctttatggtggcctgctggccaatggggacctcctg gcaatgggagaccccactctggcagaggaccataccataattgttgaggaagacaaggag gaagagagtgacttggaagataaacagagcccaacgggcagtgactctgggtcagtacaa gaagactcgggctcagagccaaagagagctctgcctttcagaaaaggtcccaattttact atggaaaagttcctagacccttctcgcccttacaagtgtaccgtctgcaaggaatctttc actcaaaagaatatcctgctagtacactacaattctgtctcccacctgcataagttaaag agagcccttcaagaatcagcaaccggtcagccagaacccaccagcagcccagacaacaaa ccttttaagtgtaacacttgtaatgtggcctacagccagagttccactctggagatccat atgaggtctgtgttacatcaaaccaaggcccgggcagccaagctggaggctgcaagtggc agcagcaatgggactgggaacagcagcagtatttccttgagctcctccacgccaagtcct gtgagcaccagtggcagtaacacctttaccacctccaatccaagcagtgctggcattgct ccaagctctaacttactaagccaagtgcccactgagagtgtagggatgccacccctgggg aatcctattggtgccaacattgcttccccttcagagcccaaagaggccaatcggaagaaa ctggcagatatgattgcatccaggcagcagcaacaacagcagcagcaacagcaacaacaa caacaacaacaacaacaacaagcacaaacgctggcccaggcccaggctcaagttcaagct cacctgcagcaggagctgcagcaacaggctgccctgatccagtctcagctgtttaacccc accctccttcctcacttccccatgacaactgagaccctgctgcaactacagcagcagcag cacctcctcttccctttctacatccccagtgctgagttccagcttaaccccgaggtgagc ttgccagtgaccagtggggcactgacactgactgggacaggcccaggcctgctggaagat ctgaaggctcaggttcaggtcccacagcagagccatcagcagatcttgccgcagcagcag cagaaccaactctctatagcccagagtcactctgccctccttcagccaagccagcacccc gaaaagaagaacaaattggtcatcaaagaaaaggaaaaagaaagccagagagagagggac agcgccgaggggggagagggcaacaccggtccgaaggaaacactgccagatgccttgaag gccaaagagaagaaagagttggcaccagggggtggttctgagccttccatgctccctcca cgcattgcttcagatgccagagggaacgccaccaaggccctgctggagaactttggcttt gagttggtcatccagtataatgagaacaagcagaaggtgcagaaaaagaatgggaagact gaccagggagagaacctggaaaagctcgagtgtgactcctgcggcaagttgttttccaac atcttgattttaaagagtcatcaagagcacgttcatcagaattactttcctttcaaacag ctcgagaggtttgccaaacagtacagagaccactacgataaactgtacccactgaggccc cagaccccagagccaccaccacctccccctccaccccctccacccccacttccggcagcg ccgcctcagccggcgtccacaccagccatccccgcatcagccccacccatcacctcacct acaattgcaccggcccagccatcagtgccgctcacccagctctccatgccgatggagctg cccatcttctcgccgctgatgatgcagacgatgccgctgcagaccttgccggctcagcta cccccgcagctgggacctgtggagcctctgcctgcggacctggcccaactctaccagcat cagctcaatccaaccctgctccagcagcagaacaagaggcctcgcaccaggatcacagat gatcagctccgagtcttgcggcaatattttgacattaacaactcccccagtgaagagcaa ataaaagagatggcagacaagtccgggttgccccagaaagtgatcaagcactggttcagg aacactctcttcaaagagaggcagcgtaacaaggactccccttacaacttcagtaatcct cctatcaccagcctggaggagctcaagattgactcccggcccccttcgccggaacctcca aagcaggagtactggggaagcaagaggtcttcaagaacaaggtttacggactaccagctg agggtcttacaggacttcttcgatgccaatgcttacccaaaggatgatgaatttgagcaa ctctctaatttactgaaccttccaacccgagtgatagtggtgtggtttcagaatgcccga cagaaggccaggaagaattatgagaatcagggagagggcaaagatggagagcggcgtgag cttacaaatgatagatacattcgaacaagcaacttgaactaccagtgcaaaaaatgtagc ctggtgtttcagcgcatctttgatctcatcaagcaccagaagaagctgtgttacaaggat gaggatgaggaggggcaggacgacagccaaaatgaggattccatggatgccatggaaatc ctgacgcctaccagctcatcctgcagtaccccgatgccctcacaggcttacagcgcccca gcaccatcagccaataatacagcttcctccgctttcttgcagcttacagcggaggctgag gaactggccaccttcaattcaaaaacagaggcaggcgatgagaaaccaaagctggcggaa gctcccagtgcacagccaaaccaaacccaagaaaagcaaggacaaccaaagccagagctg cagcagcaagagcagcccgagcagaagaccaacactccccagcagaagctcccccagctg gtgtccctgccttcgttgccacagcctcctccacaagcgccccctccacagtgcccctta ccccagtcgagccccagtccttcccagctctcccacctgcccctcaagcccctccacaca tcaactcctcaacagctcgcaaacctacctcctcagctaatcccctaccagtgtgaccag tgtaagttggcatttccgtcatttgagcactggcaggagcatcagcagctccacttcctg agcgcgcagaaccagttcatccacccccagtttttggacaggtccctggatatgcctttc atgctctttgatcccagtaacccactcctggccagccagctgctctctggggccatacct cagattccagcaagctcagccacttctccttcaactccaacctccacaatgaacactctc aagaggaagctggaggaaaaggccagtgcaagccctggcgaaaacgacagtgggacagga ggagaagagcctcagagagacaagcgtttgagaacaaccatcacaccggaacaactagaa attctctaccagaagtatctactggattccaatccgactcgaaagatgttggatcacatt gcacacgaggtgggcttgaagaaacgtgtggtacaagtctggtttcagaacacccgagct cgggaaaggaaaggacagttccgggctgtaggcccagcgcaggcccacaggagatgccct ttttgcagagcgctcttcaaagccaagactgctcttgaggctcatatccggtcccgtcac tggcatgaagccaagagagctggctacaacctaactctgtctgcgatgctcttagactgt gatgggggactccagatgaaaggagatatttttgacggaactagcttttcccacctaccc ccaagcagtagtgatggtcagggtgtccccctctcacctgtgagtaaaaccatggaattg tcacccagaactcttctaagcccttcctccattaaggtggaagggattgaagactttgaa agcccctccatgtcctcagttaatctaaactttgaccaaactaagctggacaacgatgac tgttcctctgtcaacacagcaatcacagataccacaactggagacgagggcaacgcagat aacgacagtgcaacgggaatagcaactgaaaccaaatcctcttctgcacccaacgaaggg ttgaccaaagcggccatgatggcaatgtctgagtatgaagatcggttgtcatctggtctg gtcagcccggccccgagcttttatagcaaggaatatgacaatgaaggtacagtggactac agtgaaacctcaagccttgcagatccctgctccccgagtcctggtgcgagtggatctgca ggcaaatctggtgacagcggagatcggcctgggcagaaacgttttcgcactcaaatgacc aatctgcagctgaaggtcctcaagtcatgctttaatgactacaggacacccactatgcta gaatgtgaggtcctgggcaatgacattggactgccaaagagagtcgttcaggtctggttc cagaatgcccgggcaaaagaaaagaagtccaagttaagcatggccaagcattttggtata aaccaaacgagttatgagggacccaaaacagagtgcactttgtgtggcatcaagtacagc gctcggctgtctgtacgtgaccatatcttttcccaacagcatatctccaaagttaaagac accattggaagccagctggacaaggagaaagaatactttgacccagccaccgtacgtcag ttgatggctcaacaagagttggaccggattaaaaaggccaacgaggtccttggactggca gctcagcagcaagggatgtttgacaacacccctcttcaggcccttaaccttcctacagca tatccagcgctccagggcattcctcctgtgttgctcccgggcctcaacagcccctccttg ccaggctttactccatccaacacagctttaacgtctcctaagccgaacttgatgggtctg cccagcacaactgttccttcccctggcctccccacttctggattaccaaataaaccgtcc tcagcgtcgctgagctccccaaccccagcacaagccacgatggcgatgggccctcagcaa cccccccagcagcagcagcagcagcagcaaccacaggtgcagcagcctcccccgccgcca gcagcccagccgccacccacaccacagctcccactgcaacagcagcagcaacgcaaggac aaagacagtgagaaagtaaaggagaaggaaaaggcacacaaagggaaaggggaacccctg cctgtccccaagaaggagaaaggagaggcccccacggcaactgcagccacgatctcagcc ccgctgcccaccatggagtatgcggtagaccctgcacagctgcaggccctgcaggccgcg ttgacttcggaccccacagcattgctcacaagccagttccttccttactttgtaccaggc ttttctccttattatgctccccagatccctggcgccctgcagagcgggtacctgcagcct atgtatggcatggaaggcctgttcccctacagccctgcactgtcgcaggccctgatgggg ctgtccccaggctccctactgcagcagtaccagcaataccagcagagtctgcaggaggca attcagcagcagcagcagcggcaactacagcagcagcagcagcaaaaagtgcagcagcag cagcccaaagcaagccaaaccccagtcccccccggggctccttccccagacaaagaccct gccaaagaatcccccaaaccagaagaacagaaaaacaccccccgtgaggtgtcccccctc ctgccgaaactccctgaagagccagaagcagaaagcaaaagtgcggactccctctacgac cccttcattgttccaaaggtgcagtacaagttggtctgccgcaagtgccaggcgggcttc agcgacgaggaggcagcgaggagccacctgaagtccctctgcttcttcggccagtctgtg gtgaacctgcaagagatggtgcttcacgtccccaccggcggcggcggcggtggcagtggc ggcggcggcggcggtggcggcggcggcggcggcggcggctcgtaccactgcctggcgtgc gagagcgcgctctgtggggaggaagctctgagtcaacatctcgagtcggccttgcacaaa cacagaacaatcacgagagcagcaagaaacgccaaagagcaccctagtttattacctcac tctgcctgcttccccgatcctagcaccgcatctacctcgcagtctgccgctcactcaaac gacagcccccctcccccgtcggccgccgccccctcctccgcttccccccacgcctccagg aagtcttggccgcaagtggtctcccgggcttcggcagcgaagcccccttcttttcctcct ctctcctcatcttcaacggttacctcaagttcatgcagcacctcaggggttcagccctcg atgccaacagacgactattcggaggagtctgacacggatctcagccaaaagtccgacgga ccggcgagcccggtggagggtcccaaagaccccagctgccccaaggacagtggtctgacc agtgtaggaacggacaccttcagattgtaa |
Protein Sequence |
>463 : length: 2789 MRLGGGQLVSEELMNLGESFIQTNDPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSED EWKAVMGDSYQCKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAI GNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCN YSTKAKLNLIQHVRSMKHQRSESLRKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEAIE DVEGPSETAADPEELAKDQEGGASSSQAEKELTDSPATSKRISFPGSSESPLSSKRPKTA EEIKPEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHL HSVAPDCVEKLIMTVTTPEMVMPSSMFLPAAVPDRDGNSNLEEAGKQPETSEDLGKNILP SASTEQSGDLKPSPADPGSVREDSGFICWKKGCNQVFKTSAALQTHFNEVHAKRPQLPVS DRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRTFQALKKHLETSHLE LSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKEEESDLEDKQSPTGSDSGSVQ EDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLK RALQESATGQPEPTSSPDNKPFKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAASG SSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVGMPPLG NPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQA HLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVS LPVTSGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQHP EKKNKLVIKEKEKESQRERDSAEGGEGNTGPKETLPDALKAKEKKELAPGGGSEPSMLPP RIASDARGNATKALLENFGFELVIQYNENKQKVQKKNGKTDQGENLEKLECDSCGKLFSN ILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAA PPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQL PPQLGPVEPLPADLAQLYQHQLNPTLLQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQ IKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLEELKIDSRPPSPEPP KQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNAR QKARKNYENQGEGKDGERRELTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKD EDEEGQDDSQNEDSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAE ELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQL VSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQ CKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIP QIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQLE ILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGPAQAHRRCP FCRALFKAKTALEAHIRSRHWHEAKRAGYNLTLSAMLLDCDGGLQMKGDIFDGTSFSHLP PSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFESPSMSSVNLNFDQTKLDNDD CSSVNTAITDTTTGDEGNADNDSATGIATETKSSSAPNEGLTKAAMMAMSEYEDRLSSGL VSPAPSFYSKEYDNEGTVDYSETSSLADPCSPSPGASGSAGKSGDSGDRPGQKRFRTQMT NLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKSKLSMAKHFGI NQTSYEGPKTECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQ LMAQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSL PGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQ PPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPL PVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPG FSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEA IQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREVSPL LPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSV VNLQEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHK HRTITRAARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSPPPPSAAAPSSASPHASR KSWPQVVSRASAAKPPSFPPLSSSSTVTSSSCSTSGVQPSMPTDDYSEESDTDLSQKSDG PASPVEGPKDPSCPKDSGLTSVGTDTFRL |