| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 50943 |
Name | FOXP3 |
Synonym | AIID|DIETER|IPEX|JM2|PIDX|XPID;forkhead box P3;FOXP3;forkhead box P3 |
Definition | FOXP3delta7|forkhead box protein P3|immune dysregulation, polyendocrinopathy, enteropathy, X-linked|immunodeficiency, polyendocrinopathy, enteropathy, X-linked|scurfin |
Position | Xp11.23 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 7355 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | IL2 signaling events mediated by STAT5;PID Curated;200158 |
Pathway | Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039 |
Disease | Other well-defined immunodeficiency syndromes;KEGG DISEASE;H00107 |
Disease | diabetes, type 1;GAD |
Disease | IMMUNE;GAD |
Disease | Immune system diseases;KEGG DISEASE |
Disease | Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked;OMIM |
Disease | Diabetes mellitus, type I, susceptibility to;OMIM |
Disease | Primary immunodeficiency;KEGG DISEASE |
|
External Links |
|
Links to Entrez Gene | 50943 |
Links to all GeneRIF Items | 50943 |
Links to iHOP | 50943 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>50943 : length: 1191 atgcccaaccccaggcctggcaagccctcggccccttccttggcccttggcccatcccca ggagcctcgcccagctggagggctgcacccaaagcctcagacctgctgggggcccggggc ccagggggaaccttccagggccgagatcttcgaggcggggcccatgcctcctcttcttcc ttgaaccccatgccaccatcgcagctgcagctctcaacggtggatgcccacgcccggacc cctgtgctgcaggtgcaccccctggagagcccagccatgatcagcctcacaccacccacc accgccactggggtcttctccctcaaggcccggcctggcctcccacctgggatcaacgtg gccagcctggaatgggtgtccagggagccggcactgctctgcaccttcccaaatcccagt gcacccaggaaggacagcaccctttcggctgtgccccagagctcctacccactgctggca aatggtgtctgcaagtggcccggatgtgagaaggtcttcgaagagccagaggacttcctc aagcactgccaggcggaccatcttctggatgagaagggcagggcacaatgtctcctccag agagagatggtacagtctctggagcagcagctggtgctggagaaggagaagctgagtgcc atgcaggcccacctggctgggaaaatggcactgaccaaggcttcatctgtggcatcatcc gacaagggctcctgctgcatcgtagctgctggcagccaaggccctgtcgtcccagcctgg tctggcccccgggaggcccctgacagcctgtttgctgtccggaggcacctgtggggtagc catggaaacagcacattcccagagttcctccacaacatggactacttcaagttccacaac atgcgaccccctttcacctacgccacgctcatccgctgggccatcctggaggctccagag aagcagcggacactcaatgagatctaccactggttcacacgcatgtttgccttcttcaga aaccatcctgccacctggaagaacgccatccgccacaacctgagtctgcacaagtgcttt gtgcgggtggagagcgagaagggggctgtgtggaccgtggatgagctggagttccgcaag aaacggagccagaggcccagcaggtgttccaaccctacacctggcccctga |
Protein Sequence |
>50943 : length: 396 MPNPRPGKPSAPSLALGPSPGASPSWRAAPKASDLLGARGPGGTFQGRDLRGGAHASSSS LNPMPPSQLQLSTVDAHARTPVLQVHPLESPAMISLTPPTTATGVFSLKARPGLPPGINV ASLEWVSREPALLCTFPNPSAPRKDSTLSAVPQSSYPLLANGVCKWPGCEKVFEEPEDFL KHCQADHLLDEKGRAQCLLQREMVQSLEQQLVLEKEKLSAMQAHLAGKMALTKASSVASS DKGSCCIVAAGSQGPVVPAWSGPREAPDSLFAVRRHLWGSHGNSTFPEFLHNMDYFKFHN MRPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCF VRVESEKGAVWTVDELEFRKKRSQRPSRCSNPTPGP |