Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

53353

Name

LRP1B

Synonym

LRP-DIT|LRPDIT;low density lipoprotein receptor-related protein 1B;LRP1B;low density lipoprotein receptor-related protein 1B

Definition

LRP-1B|LRP-deleted in tumors|low density lipoprotein receptor related protein-deleted in tumor|low density lipoprotein-related protein 1B (deleted in tumors)|low-density lipoprotein receptor-related protein 1B|low-density lipoprotein receptor-related prot

Position

2q21.2

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

10007

TUSON P-value

1

Pathways and Diseases

Pathway

Alzheimer disease-presenilin pathway;PANTHER;P00004

Disease

aging;GAD

Disease

Erectile dysfunction and prostate cancer treatment;NHGRI

Disease

Body mass index;NHGRI

Disease

Aging;NHGRI

Disease

AGING;GAD

Disease

Optic disc size (disc);NHGRI

External Links

Links to Entrez Gene

53353

Links to all GeneRIF Items

53353

Links to iHOP

53353

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>53353 : length: 13800
atgtccgagtttctcctcgccttactcactctctcgggattattgccgattgccagggtg
ctgaccgtgggagccgaccgagatcagcagttgtgtgatcctggtgaatttctttgccac
gatcacgtgacttgtgtctcccagagctggctgtgtgatggggaccctgactgccctgat
gattcagacgagtctttagatacctgtcccgaggaggtagaaatcaagtgccccttgaat
cacattgcttgccttggtaccaacaaatgtgttcatttatcccagctgtgcaatggtgtc
ttggactgcccagatgggtatgacgaaggagtacattgtcaggaactgttatccaattgc
caacagctgaattgtcagtataaatgtacaatggtcagaaatagtacaagatgttactgt
gaggatggattcgaaataacagaagatgggagaagctgtaaagatcaagatgaatgtgct
gtttatggtacatgcagccagacctgcagaaacacacatggatcctacacttgcagttgt
gtggaaggctacctaatgcagccagacaacagatcttgcaaggctaaaattgaacctaca
gatagaccacctatactattaattgcaaattttgaaacaattgaggttttctatcttaat
ggaagtaaaatggcaactctaagctcagtcaatggaaatgaaattcatactctggatttt
atttataatgaagatatgatttgttggattgaatcaagagaatcttcaaatcaactcaaa
tgtatccagataacaaaagcaggaggattaacagatgaatggacaatcaatattcttcaa
tccttccacaatgtgcaacaaatggcgattgactggctcactcgaaatctctattttgtg
gaccatgtcggtgaccggatctttgtttgtaattccaacggttctgtatgtgtcaccctg
attgatctggagcttcacaatcctaaagcaatagcagtagatccaatagcaggaaaactt
ttctttactgactacgggaatgtcgccaaagtggagagatgtgacatggatgggatgaac
cgaacaaggataattgattcaaagacagagcagccagctgcactggcactagacctagtc
aacaaattggtttactgggtagatctttacttggactatgtgggagtagtggactatcaa
ggaaaaaatagacacactgtcattcaaggcagacaagttagacatctttatggtataact
gtgtttgaagattatttgtatgcaaccaattctgataactacaatatcgtaaggataaac
cgatttaatgggactgatattcactcattaattaaaattgagaatgcttggggaatccga
atttatcaaaaaagaactcaaccaacagtcagaagccatgcatgtgaagtcgatccatat
ggaatgccagggggctgttcacacatctgtctactcagcagcagttacaaaactcggact
tgtcgctgcaggactggcttcaacttgggaagtgatggcaggtcatgcaaaagaccaaag
aatgagttgttcctcttttatgggaaaggacgcccaggaattgttagaggaatggacttg
aataccaagatagctgatgaatacatgatccccatagaaaatctggtaaaccctcgtgct
ttagactttcacgcagaaaccaattacatctactttgctgacaccaccagtttcctaatt
ggccggcagaagatagatggcacagagagagaaaccatcctgaaagatgatctggataat
gtagagggcattgctgtggactggattggaaataatctttactggaccaatgatggccat
aggaaaaccattaatgtggccaggctggaaaaagcttctcagagtcggaagactctttta
gagggtgaaatgtctcatcccagaggaattgtggtggatccagttaatggttggatgtat
tggacagactgggaggaagatgaaatagatgacagcgtgggaaggattgagaaggcctgg
atggatggattcaatcggcagatttttgtgacttcaaagatgctgtggccaaacggttta
actctggactttcacaccaacacattatactggtgtgatgcctattacgatcatattgaa
aaagtatttttgaatgggactcacaggaagattgtttacagtgggagagagttgaaccac
cctttcggactgtcgcatcatggaaattatgtgttctggactgattatatgaatggttcc
atttttcaactagatttgataacaagtgaggtgacattgctgaggcatgaaagaccaccc
ctatttgggcttcagatttatgatccacgaaagcaacaaggtgacaatatgtgccgagta
aataatgggggctgtagtacactttgcttggctatcccaggaggccgggtgtgtgcttgt
gccgataatcaacttttggatgaaaatgggacaacttgcacatttaatcctggagaagca
ctacctcacatatgtaaagctggagagtttcgctgcaaaaacagacactgtatccaagct
cggtggaaatgtgatggcgacgatgactgcctagacggaagcgatgaggattcagtaaac
tgcttcaatcatagctgtcctgatgatcagtttaaatgccagaataatcgctgcatcccc
aagagatggctttgtgatggagctaatgactgtgggagcaatgaagatgaatccaatcaa
acttgcacagccagaacatgccaggtagaccagttttcttgcggaaatgggcgttgcatt
cccagagcatggctgtgtgacagggaagacgactgtggtgaccagacagatgaaatggca
tcttgtgaattcccaacttgtgagccactaacccaattcgtatgcaaaagtggaagatgc
attagcagcaaatggcactgcgactctgatgacgactgtggggacgggagtgatgaggtg
ggctgtgttcactcttgctttgataatcagttcagatgttccagtggcagatgcatccca
ggccactgggcctgtgatggtgacaatgactgtggggacttcagtgatgaagcccagatc
aattgtactaaagaagagattcattctcctgctggttgtaacggaaatgaatttcagtgc
caccctgatggtaattgcgttcctgatttgtggcgctgtgatggagaaaaagactgtgaa
gatggtagtgatgaaaaaggttgcaatggtaccatacgattgtgtgaccacaaaaccaag
ttttcctgttggagtacagggagatgcatcaacaaagcatgggtgtgtgatggagatatt
gattgcgaagatcagtcagatgaagatgactgtgacagtttcttgtgtggaccacccaag
catccttgtgctaatgacacctcagtctgcctgcagccagagaaactctgcaatgggaaa
aaggattgtcctgatggctctgatgaaggctatctctgtgatgagtgttcgctgaacaat
ggaggctgtagcaaccactgttctgttgttcctggaagaggaattgtctgttcctgccct
gaaggacttcaactcaacaaagacaataaaacatgtgaaattgtggattattgtagcaat
catctaaagtgcagccaagtatgtgagcagcacaagcacacagtcaagtgctcatgttat
gaaggttggaagctggatgtagacggtgaaagttgtacaagtgttgatccttttgaagca
ttcatcatcttttctattcgtcatgagatcagaaggattgatcttcacaaaagagactat
agtctacttgttcctggattgagaaacacaatagcacttgattttcacttcaatcaaagt
ttactttattggacagatgttgtagaagacagaatataccggggaaagctttctgaaagt
ggaggtgtcagtgccattgaagtggttgtggagcatggcctggctactccagaaggcctg
acagtcgactggatagcaggaaacatatactggatagacagcaatctggaccaaatcgaa
gtggccaaactagatggctccctaagaactacactaatagcaggagccatggaacacccc
agggccattgctttggacccaagatatggaattcttttctggacagactgggatgcaaat
tttcctcgcattgaatctgcctctatgagtggtgctgggagaaaaaccatctataaagac
atgaaaactggggcttggcctaatggactaactgtggaccactttgagaaaaggatagtg
tggacagacgccaggtcagatgctatttattcagccctctatgatggaacaaacatgata
gaaatcatccgaggtcatgaatacctttcccatccctttgctgtgtctctatatgggagt
gaagtctactggacagactggaggaccaacacattgtccaaagccaataagtggacaggg
cagaatgtcagtgtgattcagaaaaccagtgcacagccatttgaccttcagatataccat
cccagtcgccagccacaggctcccaatccttgtgcagctaatgatggcaaaggcccctgc
tctcacatgtgtctaatcaatcacaataggagtgctgcctgtgcgtgcccccacttgatg
aagctttcttcagacaagaagacctgctatgaaatgaaaaaatttcttctttatgcaaga
cgttctgaaatcagaggagtggatattgacaatccatactttaacttcatcacggcattt
acagtccctgatattgatgacgttactgtgatagacttcgatgcatctgaggaacgttta
tactggacagatattaaaacacaaaccattaaacgagcttttattaacggaactgggtta
gaaactgttatttcaagagatattcagagtatcagagggctagcagtggattgggtgtca
cgtaatttatactggattagctcagaatttgatgaaacgcaaattaatgtggcaaggcta
gatggctctttgaaaacctcaattatccatggaatcgataagccacagtgtcttgcagct
cacccagtcaggggaaaactctactggaccgatggaaacacaattaacatggcaaatatg
gatggcagtaatagcaagattctgtttcagaatcagaaggagccagttggtctatcgata
gactatgtggaaaacaagctttattggatcagttcagggaatggaaccataaatagatgc
aacctggatggtggtaatttagaagtaatcgagtcaatgaaagaagaattaacaaaagct
acagccctaaccatcatggataagaaactgtggtgggcagaccaaaacttagcccagcta
ggaacctgcagcaaaagagacggaagaaaccccaccatcctacggaataagacttctggg
gtagttcatatgaaagtctatgataaagaagcacagcaaggcagcaattcctgccaacta
aacaatggtggatgctctcaactttgtttaccaacatctgaaactacaaggacttgtatg
tgtacagtgggatattatctccaaaagaaccgtatgtcatgtcaaggtatagaatcattt
cttatgtactctgttcatgaaggaatcaggggaatacctcttgaaccaagtgacaaaatg
gatgctttgatgcctatatcaggaacttcatttgccgtgggaatagatttccatgcagaa
aatgataccatctactggacagacatgggcttcaataaaattagcagagctaaaagagat
cagacttggaaagaagatatcattaccaatggcttgggaagagtggaagggatagctgtt
gactggattgctggtaacatatattggacagatcatggtttcaacttaattgaagttgca
agactcaatggttctttccgttatgtaattatttcccaaggcctggatcaaccaagatct
atagctgtgcacccagagaaaggcctcttgttctggactgaatggggacaaatgccctgt
attggaaaggctcgcttggatggctcagagaaggttgtccttgtaagcatgggaatagca
tggccgaatggcatctccatcgactatgaggaaaataaattgtactggtgtgatgctcgc
acagacaagatagagagaatcgaccttgagactggagggaatcgcgagatggtgctgtca
ggaagcaatgtggatatgttttcagttgcagtctttggggcttacatctactggtctgac
agagcacatgcaaacgggtctgtcagaaggggccacaagaatgatgccacagaaacgata
accatgagaaccggccttggagtcaacctgaaggaggttaaaatatttaaccgagtaaga
gagaaagggaccaatgtttgtgccagggacaatggtggctgtaagcaactctgtctttat
cgaggaaattcccggagaacttgtgcttgtgcccatggatatttggcagaagatggagtt
acttgcctgaggcatgaaggctatttactgtattcaggaagaacaatattaaaaagtata
catctttctgatgaaaccaatttaaattccccaataaggccatatgagaatccacgttat
ttcaagaatgtcatagccttggcttttgactataatcaaagaagaaaaggtaccaaccga
atcttttacagtgatgcacactttggaaatatacagcttattaaagacaactgggaagac
agacaagtaattgttgaaaatgtgggttctgtggaaggacttgcctatcacagagcctgg
gatacactgtactggacaagctctaccacctcatccatcaccagacacactgtggaccag
actcggcctggagcatttgacagggaagctgtcatcaccatgtcagaagatgaccatcca
catgtgctagccttggatgaatgtcaaaatttaatgttttggaccaactggaatgaacaa
catccaagtatcatgagatctactctgactgggaaaaatgctcaagtggtggtcagtaca
gacatactcactccaaatggacttactatcgactaccgtgcagagaagctgtatttctca
gatggcagtctaggaaaaattgaaaggtgtgaatacgatggatcccagagacatgtgata
gttaaatctgggccagggactttcctcagtttggctgtttatgacaattatatattctgg
tcggactggggaagaagagctatactgcggtccaacaagtacacaggaggagatacaaaa
attcttcgttccgatattccacatcagccaatgggaatcatagctgttgccaatgacacc
aatagctgtgaactttctccatgtgcattattgaatggaggctgccatgacttgtgcctt
ttaactcccaatgggagagtgaattgttcctgcagaggggaccgaatattgctagaggac
aacagatgtgtgactaaaaattcctcctgcaacgcttattcggagtttgaatgtggaaat
ggtgagtgcattgactaccagctcacctgtgatggcattcctcactgtaaagataaatca
gatgaaaaactgctctactgtgaaaacagaagctgtcgaagaggcttcaagccatgctat
aatcgccgctgcattcctcatggcaagttatgtgatggagaaaatgactgcggagacaac
tctgatgaattagattgtaaagtttcaacctgtgccacggttgagttccgctgtgcagat
gggacttgtattccaagatcagcacgatgcaaccagaacatagattgtgcagatgcttca
gatgaaaagaactgcaataacacagactgcacacatttctataagcttggagtgaaaacc
acagggttcataagatgtaattctacctcactgtgtgttctgccaacctggatatgcgac
gggtctaatgactgtggagactattcagatgaattaaagtgcccagttcaaaacaaacac
aaatgtgaagaaaattattttagttgtcctagtggaagatgcattttgaatacctggata
tgcgatggtcagaaagattgtgaggatggacgtgatgaattccactgtgattcttcttgc
tcttggaaccaatttgcttgttccgcacaaaaatgtatttctaagcattggatttgtgat
ggagaagatgactgtggggatgggttagatgaaagtgacagcatttgtggtgccataacc
tgtgctgctgacatgttcagctgccagggctctcgtgcctgcgtgccccgacattggctt
tgtgatggtgaaagggactgtccagatggaagcgatgagctttccacagcaggctgcgct
cccaataatacatgtgatgaaaatgctttcatgtgccataataaagtatgcattcccaag
caatttgtttgtgaccatgatgacgactgtggagatggctctgatgagtcaccgcagtgt
ggatatcgacagtgtggtacagaagaatttagttgtgctgatgggcggtgtcttctaaat
actcaatggcagtgtgatggagactttgactgtcctgaccattctgatgaagcaccttta
aacccaaagtgtaaaagtgcagaacagtcatgcaacagttcattttttatgtgcaaaaat
ggcaggtgcattcccagtggaggtctttgcgacaataaggatgactgtggcgatggttca
gatgagagaaactgccatataaatgaatgtttgagtaagaaagtcagtggatgttctcaa
gactgtcaagaccttccggtcagttataagtgcaaatgctggcctggattccaactgaag
gatgacggcaaaacatgtgtagacattgatgaatgctcttcaggctttccctgtagccag
caatgcatcaatacatacgggacttacaagtgcctctgtacagatgggtatgaaatacaa
cctgataacccaaatggctgcaaatcgctctcagatgaagaaccttttttaattcttgct
gatcatcatgagataaggaaaattagcactgatggctccaactacacacttttaaaacag
ggattaaacaatgttattgctatagactttgattacagagaagaattcatctattggatc
gattctagccgacccaatggcagtcgcataaatagaatgtgtttaaatggaagtgacatt
aaggtagttcataacacagcggtccccaatgcacttgctgtcgattggattggaaaaaac
ctctattggtctgacacagaaaaaagaatcattgaagtatccaaactcaatggcttgtac
cctactatactcgttagcaaaaggctgaagtttcccagagacttgtctttagatcctcaa
gctggatatttgtattggattgactgctgcgagtatcctcatattggccgtgttggaatg
gatggaaccaatcagagtgttgtcatagaaaccaagatttctagacctatggcactaaca
atagattatgttaatcgtagactctactgggccgatgaaaatcacattgaatttagcaac
atggatggatctcatagacacaaagtccctaatcaagatattccaggggtgattgcacta
acattgtttgaagactacatctactggactgatgggaaaaccaagtcactcagccgtgcc
cataaaacatcgggagcagacagactctcactgatttactcatggcatgccatcacagat
atccaggtgtatcattcttatagacaacctgatgtctccaaacatctctgcatgataaat
aatggtggttgcagtcatttgtgccttttagcccctggaaaaacccacacttgtgcatgt
cccactaacttctatctggcagctgataataggacttgcttatccaactgcacagccagc
cagtttcgttgcaaaactgacaaatgtattccattctggtggaaatgtgacaccgtggat
gactgtggtgatggatctgatgaacctgatgactgtcctgaatttagatgtcagccaggc
cgatttcagtgtgggactggactctgtgctctaccagctttcatctgtgatggagagaat
gattgtggagacaattctgatgaactcaactgtgacacacatgtctgcctgtcaggtcaa
ttcaaatgtaccaagaaccagaaatgtatcccagtaaacttaagatgtaatgggcaagat
gactgtggtgatgaggaagatgaaagagactgtcctgaaaacagctgttctccagactat
ttccagtgtaagactacgaagcattgcatttccaagctgtgggtttgtgacgaggatcca
gactgtgcagatgcatcagacgaggccaactgcgataaaaagacttgtggacctcatgaa
ttccagtgtaaaaacaacaactgtattcccgatcactggcggtgtgatagccaaaatgac
tgcagtgataattcagatgaagaaaactgtaagccacagacatgtacattgaaagatttc
ctctgtgccaatggggactgtgtttcttcaaggttttggtgtgatggagattttgactgt
gcagatggctctgatgagagaaattgtgagacaagttgttccaaagatcagttccggtgt
tccaatggtcagtgtataccagcaaaatggaaatgtgatggccatgaagactgcaaatat
ggggaagatgagaaaagctgtgagccagcttctcctacttgctcatcacgtgaatatata
tgtgccagtgatggatgtatttcagcatctttgaaatgtaatggagaatatgattgtgct
gatggttcagatgagatggactgtgtgactgaatgtaaggaagatcagtttcggtgcaaa
aataaagcccactgtattccaattagatggctgtgtgatggaattcatgactgtgtggat
ggcagtgatgaagagaactgtgaaagaggaggaaatatatgtagagctgatgagttcctt
tgcaataattctctctgcaaactacatttctgggtgtgtgatggagaggacgactgtgga
gacaactctgatgaagcccctgatatgtgtgtcaaatttctttgtccatccacgagacct
cacagatgcagaaataacagaatatgcctacagtcggagcaaatgtgcaatgggattgat
gaatgcggtgacaattcagatgaagatcactgtggtggtaagctgacatataaagcaagg
ccttgtaaaaaggatgagtttgcttgtagtaataaaaaatgcatccctatggatctccag
tgtgatcgacttgatgactgcggagatggttcagatgagcaaggatgcagaatagctcct
actgaatatacctgtgaagataatgtgaatccatgtggagatgatgcatattgtaatcaa
ataaaaacatctgttttctgtcgctgtaagcctggatttcagagaaacatgaaaaacaga
caatgtgaagaccttaatgaatgtttggtgtttggcacatgttcccatcaatgtataaat
gtggaaggatcatataaatgtgtgtgtgaccagaattttcaagaaagaaataacacctgc
atagcagaaggctctgaagatcaagttctctacattgctaatgacactgatatcctgggt
tttatatatccattcaactacagtggcgatcatcaacaaatttctcatattgaacataat
tcaagaataacagggatggatgtatattatcaaagagatatgattatttggagtactcag
tttaatccaggcggaattttctacaaaaggatccatggcagagaaaaaaggcaagcaaac
agtggcttgatttgtcctgaatttaaaaggcccagggacattgcagttgactgggtggct
ggaaacatttactggactgatcattctagaatgcattggttcagttactacactactcac
tggaccagtctgaggtactctatcaacgtagggcagctgaatggccccaactgcaccaga
ctcttaacaaatatggctggagaaccctatgctattgcagtaaatcctaaaagagggatg
atgtactggactgttgttggggatcattcccatatagaagaagcagccatggatggtaca
ctgagaaggattttagtacaaaagaacttacagagacccacaggtttggctgtggattat
tttagtgaacgcatatattgggctgactttgagctctccatcattggcagtgttctgtat
gatggctctaattcagtagtctctgtcagcagcaaacaaggtttattacatccacatagg
atcgatatctttgaagattatatatatggagcaggacctaaaaatggtgtatttcgagtt
caaaaatttggccatggttcagtagagtacttagctttaaatattgataaaacaaaaggt
gttttgatatctcatcgttataaacaactagatttacccaatccatgcttggatttagca
tgcgaatttctttgcttgctaaatccttctggggccacttgtgtgtgtccagaaggaaaa
tatttgattaatggcacctgcaatgatgacagcctgttagatgattcatgtaagttaact
tgtgaaaatggaggaagatgcattttaaatgagaaaggtgatttgaggtgtcactgttgg
cccagttattcaggagaaagatgtgaagtcaaccactgtagcaactactgccagaatgga
ggaacttgcgtaccatcagttctagggagacccacctgcagctgtgcactgggtttcact
gggccaaactgtggtaagacagtctgtgaggatttttgtcaaaatggaggaacctgcatt
gtgactgctggaaaccagccttactgccactgccagccggaatacaccggagacagatgt
cagtactacgtgtgccaccactattgtgtgaattctgaatcatgtaccattggggatgat
ggaagtgttgaatgtgtctgtccaacgcgctatgaaggaccaaaatgtgaggttgacaag
tgtgtaaggtgccatggggggcactgcattataaataaagacagtgaagatatattttgc
aactgcactaatggaaagattgcctctagctgtcagttatgtgatggctactgttacaat
ggtggcacatgccagctggaccccgagacaaatgtacctgtgtgtctatgctccaccaac
tggtcaggcacacagtgtgaaaggccagccccaaagagcagcaagtctgatcatatcagc
acaagaagcattgccatcattgtgcctctcgtcctcttggtgactttgataaccacctta
gtaattggtttagtgctttgtaaaagaaaaagaaggacaaaaacaattagaagacaacct
attatcaatggaggaataaatgtagaaattggcaatccatcttataacatgtatgaggta
gatcatgatcacaacgatggaggtcttttagatcctggctttatgatagacccaacaaag
gccaggtacatagggggaggacccagtgctttcaagcttccacacacagcgccgcccatc
tacctaaactctgatttgaaaggaccactaactgctgggccaacaaattactccaatccg
gtatatgcaaaattatatatggatgggcaaaactgtcgaaactccttaggaagtgttgat
gaaaggaaagaactgcttccaaagaaaatagaaattggtataagagagacagtggcataa

Protein Sequence

>53353 : length: 4599
MSEFLLALLTLSGLLPIARVLTVGADRDQQLCDPGEFLCHDHVTCVSQSWLCDGDPDCPD
DSDESLDTCPEEVEIKCPLNHIACLGTNKCVHLSQLCNGVLDCPDGYDEGVHCQELLSNC
QQLNCQYKCTMVRNSTRCYCEDGFEITEDGRSCKDQDECAVYGTCSQTCRNTHGSYTCSC
VEGYLMQPDNRSCKAKIEPTDRPPILLIANFETIEVFYLNGSKMATLSSVNGNEIHTLDF
IYNEDMICWIESRESSNQLKCIQITKAGGLTDEWTINILQSFHNVQQMAIDWLTRNLYFV
DHVGDRIFVCNSNGSVCVTLIDLELHNPKAIAVDPIAGKLFFTDYGNVAKVERCDMDGMN
RTRIIDSKTEQPAALALDLVNKLVYWVDLYLDYVGVVDYQGKNRHTVIQGRQVRHLYGIT
VFEDYLYATNSDNYNIVRINRFNGTDIHSLIKIENAWGIRIYQKRTQPTVRSHACEVDPY
GMPGGCSHICLLSSSYKTRTCRCRTGFNLGSDGRSCKRPKNELFLFYGKGRPGIVRGMDL
NTKIADEYMIPIENLVNPRALDFHAETNYIYFADTTSFLIGRQKIDGTERETILKDDLDN
VEGIAVDWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGEMSHPRGIVVDPVNGWMY
WTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLWPNGLTLDFHTNTLYWCDAYYDHIE
KVFLNGTHRKIVYSGRELNHPFGLSHHGNYVFWTDYMNGSIFQLDLITSEVTLLRHERPP
LFGLQIYDPRKQQGDNMCRVNNGGCSTLCLAIPGGRVCACADNQLLDENGTTCTFNPGEA
LPHICKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNHSCPDDQFKCQNNRCIP
KRWLCDGANDCGSNEDESNQTCTARTCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMA
SCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVGCVHSCFDNQFRCSSGRCIP
GHWACDGDNDCGDFSDEAQINCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCE
DGSDEKGCNGTIRLCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPK
HPCANDTSVCLQPEKLCNGKKDCPDGSDEGYLCDECSLNNGGCSNHCSVVPGRGIVCSCP
EGLQLNKDNKTCEIVDYCSNHLKCSQVCEQHKHTVKCSCYEGWKLDVDGESCTSVDPFEA
FIIFSIRHEIRRIDLHKRDYSLLVPGLRNTIALDFHFNQSLLYWTDVVEDRIYRGKLSES
GGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGAMEHP
RAIALDPRYGILFWTDWDANFPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHFEKRIV
WTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTG
QNVSVIQKTSAQPFDLQIYHPSRQPQAPNPCAANDGKGPCSHMCLINHNRSAACACPHLM
KLSSDKKTCYEMKKFLLYARRSEIRGVDIDNPYFNFITAFTVPDIDDVTVIDFDASEERL
YWTDIKTQTIKRAFINGTGLETVISRDIQSIRGLAVDWVSRNLYWISSEFDETQINVARL
DGSLKTSIIHGIDKPQCLAAHPVRGKLYWTDGNTINMANMDGSNSKILFQNQKEPVGLSI
DYVENKLYWISSGNGTINRCNLDGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQL
GTCSKRDGRNPTILRNKTSGVVHMKVYDKEAQQGSNSCQLNNGGCSQLCLPTSETTRTCM
CTVGYYLQKNRMSCQGIESFLMYSVHEGIRGIPLEPSDKMDALMPISGTSFAVGIDFHAE
NDTIYWTDMGFNKISRAKRDQTWKEDIITNGLGRVEGIAVDWIAGNIYWTDHGFNLIEVA
RLNGSFRYVIISQGLDQPRSIAVHPEKGLLFWTEWGQMPCIGKARLDGSEKVVLVSMGIA
WPNGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNVDMFSVAVFGAYIYWSD
RAHANGSVRRGHKNDATETITMRTGLGVNLKEVKIFNRVREKGTNVCARDNGGCKQLCLY
RGNSRRTCACAHGYLAEDGVTCLRHEGYLLYSGRTILKSIHLSDETNLNSPIRPYENPRY
FKNVIALAFDYNQRRKGTNRIFYSDAHFGNIQLIKDNWEDRQVIVENVGSVEGLAYHRAW
DTLYWTSSTTSSITRHTVDQTRPGAFDREAVITMSEDDHPHVLALDECQNLMFWTNWNEQ
HPSIMRSTLTGKNAQVVVSTDILTPNGLTIDYRAEKLYFSDGSLGKIERCEYDGSQRHVI
VKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGDTKILRSDIPHQPMGIIAVANDT
NSCELSPCALLNGGCHDLCLLTPNGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECGN
GECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDN
SDELDCKVSTCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNNTDCTHFYKLGVKT
TGFIRCNSTSLCVLPTWICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSGRCILNTWI
CDGQKDCEDGRDEFHCDSSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSICGAIT
CAADMFSCQGSRACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMCHNKVCIPK
QFVCDHDDDCGDGSDESPQCGYRQCGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPL
NPKCKSAEQSCNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQ
DCQDLPVSYKCKCWPGFQLKDDGKTCVDIDECSSGFPCSQQCINTYGTYKCLCTDGYEIQ
PDNPNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGLNNVIAIDFDYREEFIYWI
DSSRPNGSRINRMCLNGSDIKVVHNTAVPNALAVDWIGKNLYWSDTEKRIIEVSKLNGLY
PTILVSKRLKFPRDLSLDPQAGYLYWIDCCEYPHIGRVGMDGTNQSVVIETKISRPMALT
IDYVNRRLYWADENHIEFSNMDGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRA
HKTSGADRLSLIYSWHAITDIQVYHSYRQPDVSKHLCMINNGGCSHLCLLAPGKTHTCAC
PTNFYLAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFRCQPG
RFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIPVNLRCNGQD
DCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANCDKKTCGPHE
FQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLCANGDCVSSRFWCDGDFDC
ADGSDERNCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYI
CASDGCISASLKCNGEYDCADGSDEMDCVTECKEDQFRCKNKAHCIPIRWLCDGIHDCVD
GSDEENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPSTRP
HRCRNNRICLQSEQMCNGIDECGDNSDEDHCGGKLTYKARPCKKDEFACSNKKCIPMDLQ
CDRLDDCGDGSDEQGCRIAPTEYTCEDNVNPCGDDAYCNQIKTSVFCRCKPGFQRNMKNR
QCEDLNECLVFGTCSHQCINVEGSYKCVCDQNFQERNNTCIAEGSEDQVLYIANDTDILG
FIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGIFYKRIHGREKRQAN
SGLICPEFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTR
LLTNMAGEPYAIAVNPKRGMMYWTVVGDHSHIEEAAMDGTLRRILVQKNLQRPTGLAVDY
FSERIYWADFELSIIGSVLYDGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAGPKNGVFRV
QKFGHGSVEYLALNIDKTKGVLISHRYKQLDLPNPCLDLACEFLCLLNPSGATCVCPEGK
YLINGTCNDDSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGERCEVNHCSNYCQNG
GTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHCQPEYTGDRC
QYYVCHHYCVNSESCTIGDDGSVECVCPTRYEGPKCEVDKCVRCHGGHCIINKDSEDIFC
NCTNGKIASSCQLCDGYCYNGGTCQLDPETNVPVCLCSTNWSGTQCERPAPKSSKSDHIS
TRSIAIIVPLVLLVTLITTLVIGLVLCKRKRRTKTIRRQPIINGGINVEIGNPSYNMYEV
DHDHNDGGLLDPGFMIDPTKARYIGGGPSAFKLPHTAPPIYLNSDLKGPLTAGPTNYSNP
VYAKLYMDGQNCRNSLGSVDERKELLPKKIEIGIRETVA



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