| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 54583 |
Name | EGLN1 |
Synonym | C1orf12|ECYT3|HALAH|HIF-PH2|HIFPH2|HPH-2|HPH2|PHD2|SM20|ZMYND6;egl-9 family hypoxia-inducible factor 1;EGLN1;egl-9 family hypoxia-inducible factor 1 |
Definition | HIF prolyl hydroxylase 2|HIF-prolyl hydroxylase 2|egl nine homolog 1|egl nine-like protein 1|hypoxia-inducible factor prolyl hydroxylase 2|prolyl hydroxylase domain-containing protein 2|zinc finger MYND domain-containing protein 6 |
Position | 1q42.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 6373 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Hypoxia response via HIF activation;PANTHER;P00030 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Renal cell carcinoma;KEGG PATHWAY;hsa05211 |
Pathway | HIF-1-alpha transcription factor network;PID Curated;200172 |
Disease | Hematologic diseases;KEGG DISEASE |
Disease | Congenital polycythemia;KEGG DISEASE;H00236 |
Disease | Erythrocytosis, familial, 3;OMIM |
Disease | Circulatory system diseases;KEGG DISEASE |
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External Links |
|
Links to Entrez Gene | 54583 |
Links to all GeneRIF Items | 54583 |
Links to iHOP | 54583 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>54583 : length: 1281 atggccaatgacagcggcgggcccggcgggccgagcccgagcgagcgagaccggcagtac tgcgagctgtgcgggaagatggagaacctgctgcgctgcagccgctgccgcagctccttc tactgctgcaaggagcaccagcgtcaggactggaagaagcacaagctcgtgtgccagggc agcgagggcgccctcggccacggagtgggcccacaccagcattccggccccgcgccgccg gctgcagtgccgccgcccagggccggggcccgggagcccaggaaggcagcggcgcgccgg gacaacgcctccggggacgcggccaagggaaaagtaaaggccaagcccccggccgaccca gcggcggccgcgtcgccgtgtcgtgcggccgccggcggccagggctcggcggtggctgcc gaagccgagcccggcaaggaggagccgccggcccgctcatcgctgttccaggagaaggcg aacctgtaccccccaagcaacacgcccggggatgcgctgagccccggcggcggcctgcgg cccaacgggcagacgaagcccctgccggcgctgaagctggcgctcgagtacatcgtgccg tgcatgaacaagcacggcatctgtgtggtggacgacttcctcggcaaggagaccggacag cagatcggcgacgaggtgcgcgccctgcacgacaccgggaagttcacggacgggcagctg gtcagccagaagagtgactcgtccaaggacatccgaggcgataagatcacctggatcgag ggcaaggagcccggctgcgaaaccattgggctgctcatgagcagcatggacgacctgata cgccactgtaacgggaagctgggcagctacaaaatcaatggccggacgaaagccatggtt gcttgttatccgggcaatggaacgggttatgtacgtcatgttgataatccaaatggagat ggaagatgtgtgacatgtatatattatcttaataaagactgggatgccaaggtaagtgga ggtatacttcgaatttttccagaaggcaaagcccagtttgctgacattgaacccaaattt gatagactgctgtttttctggtctgaccgtcgcaaccctcatgaagtacaaccagcatat gctacaaggtacgcaataactgtttggtattttgatgcagatgagagagcacgagctaaa gtaaaatatctaacaggtgaaaaaggtgtgagggttgaactcaataaaccttcagattcg gtcggtaaagacgtcttctag |
Protein Sequence |
>54583 : length: 426 MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQG SEGALGHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNASGDAAKGKVKAKPPADP AAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLR PNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQL VSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMV ACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKF DRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPSDS VGKDVF |