Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

54790

Name

TET2

Synonym

KIAA1546|MDS;tet methylcytosine dioxygenase 2;TET2;tet methylcytosine dioxygenase 2

Definition

methylcytosine dioxygenase TET2|probable methylcytosine dioxygenase TET2|tet oncogene family member 2

Position

4q24

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

78

TUSON P-value

4.67E-07

External Links

Links to Entrez Gene

54790

Links to all GeneRIF Items

54790

Links to iHOP

54790

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>54790 : length: 6009
atggaacaggatagaaccaaccatgttgagggcaacagactaagtccattcctgatacca
tcacctcccatttgccagacagaacctctggctacaaagctccagaatggaagcccactg
cctgagagagctcatccagaagtaaatggagacaccaagtggcactctttcaaaagttat
tatggaataccctgtatgaagggaagccagaatagtcgtgtgagtcctgactttacacaa
gaaagtagagggtattccaagtgtttgcaaaatggaggaataaaacgcacagttagtgaa
ccttctctctctgggctccttcagatcaagaaattgaaacaagaccaaaaggctaatgga
gaaagacgtaacttcggggtaagccaagaaagaaatccaggtgaaagcagtcaaccaaat
gtctccgatttgagtgataagaaagaatctgtgagttctgtagcccaagaaaatgcagtt
aaagatttcaccagtttttcaacacataactgcagtgggcctgaaaatccagagcttcag
attctgaatgagcaggaggggaaaagtgctaattaccatgacaagaacattgtattactt
aaaaacaaggcagtgctaatgcctaatggtgctacagtttctgcctcttccgtggaacac
acacatggtgaactcctggaaaaaacactgtctcaatattatccagattgtgtttccatt
gcggtgcagaaaaccacatctcacataaatgccattaacagtcaggctactaatgagttg
tcctgtgagatcactcacccatcgcatacctcagggcagatcaattccgcacagacctct
aactctgagctgcctccaaagccagctgcagtggtgagtgaggcctgtgatgctgatgat
gctgataatgccagtaaactagctgcaatgctaaatacctgttcctttcagaaaccagaa
caactacaacaacaaaaatcagtttttgagatatgcccatctcctgcagaaaataacatc
cagggaaccacaaagctagcgtctggtgaagaattctgttcaggttccagcagcaatttg
caagctcctggtggcagctctgaacggtatttaaaacaaaatgaaatgaatggtgcttac
ttcaagcaaagctcagtgttcactaaggattccttttctgccactaccacaccaccacca
ccatcacaattgcttctttctccccctcctcctcttccacaggttcctcagcttccttca
gaaggaaaaagcactctgaatggtggagttttagaagaacaccaccactaccccaaccaa
agtaacacaacacttttaagggaagtgaaaatagagggtaaacctgaggcaccaccttcc
cagagtcctaatccatctacacatgtatgcagcccttctccgatgctttctgaaaggcct
cagaataattgtgtgaacaggaatgacatacagactgcagggacaatgactgttccattg
tgttctgagaaaacaagaccaatgtcagaacacctcaagcataacccaccaatttttggt
agcagtggagagctacaggacaactgccagcagttgatgagaaacaaagagcaagagatt
ctgaagggtcgagacaaggagcaaacacgagatcttgtgcccccaacacagcactatctg
aaaccaggatggattgaattgaaggcccctcgttttcaccaagcggaatcccatctaaaa
cgtaatgaggcatcactgccatcaattcttcagtatcaacccaatctctccaatcaaatg
acctccaaacaatacactggaaattccaacatgcctggggggctcccaaggcaagcttac
acccagaaaacaacacagctggagcacaagtcacaaatgtaccaagttgaaatgaatcaa
gggcagtcccaaggtacagtggaccaacatctccagttccaaaaaccctcacaccaggtg
cacttctccaaaacagaccatttaccaaaagctcatgtgcagtcactgtgtggcactaga
tttcattttcaacaaagagcagattcccaaactgaaaaacttatgtccccagtgttgaaa
cagcacttgaatcaacaggcttcagagactgagccattttcaaactcacaccttttgcaa
cataagcctcataaacaggcagcacaaacacaaccatcccagagttcacatctccctcaa
aaccagcaacagcagcaaaaattacaaataaagaataaagaggaaatactccagactttt
cctcacccccaaagcaacaatgatcagcaaagagaaggatcattctttggccagactaaa
gtggaagaatgttttcatggtgaaaatcagtattcaaaatcaagcgagttcgagactcat
aatgtccaaatgggactggaggaagtacagaatataaatcgtagaaattccccttatagt
cagaccatgaaatcaagtgcatgcaaaatacaggtttcttgttcaaacaatacacaccta
gtttcagagaataaagaacagactacacatcctgaactttttgcaggaaacaagacccaa
aacttgcatcacatgcaatattttccaaataatgtgatcccaaagcaagatcttcttcac
aggtgctttcaagaacaggagcagaagtcacaacaagcttcagttctacagggatataaa
aatagaaaccaagatatgtctggtcaacaagctgcgcaacttgctcagcaaaggtacttg
atacataaccatgcaaatgtttttcctgtgcctgaccagggaggaagtcacactcagacc
cctccccagaaggacactcaaaagcatgctgctctaaggtggcatctcttacagaagcaa
gaacagcagcaaacacagcaaccccaaactgagtcttgccatagtcagatgcacaggcca
attaaggtggaacctggatgcaagccacatgcctgtatgcacacagcaccaccagaaaac
aaaacatggaaaaaggtaactaagcaagagaatccacctgcaagctgtgataatgtgcag
caaaagagcatcattgagaccatggagcagcatctgaagcagtttcacgccaagtcgtta
tttgaccataaggctcttactctcaaatcacagaagcaagtaaaagttgaaatgtcaggg
ccagtcacagttttgactagacaaaccactgctgcagaacttgatagccacaccccagct
ttagagcagcaaacaacttcttcagaaaagacaccaaccaaaagaacagctgcttctgtt
ctcaataattttatagagtcaccttccaaattactagatactcctataaaaaatttattg
gatacacctgtcaagactcaatatgatttcccatcttgcagatgtgtagagcaaattatt
gaaaaagatgaaggtcctttttatacccatctaggagcaggtcctaatgtggcagctatt
agagaaatcatggaagaaaggtttggacagaagggtaaagctattaggattgaaagagtc
atctatactggtaaagaaggcaaaagttctcagggatgtcctattgctaagtgggtggtt
cgcagaagcagcagtgaagagaagctactgtgtttggtgcgggagcgagctggccacacc
tgtgaggctgcagtgattgtgattctcatcctggtgtgggaaggaatcccgctgtctctg
gctgacaaactctactcggagcttaccgagacgctgaggaaatacggcacgctcaccaat
cgccggtgtgccttgaatgaagagagaacttgcgcctgtcaggggctggatccagaaacc
tgtggtgcctccttctcttttggttgttcatggagcatgtactacaatggatgtaagttt
gccagaagcaagatcccaaggaagtttaagctgcttggggatgacccaaaagaggaagag
aaactggagtctcatttgcaaaacctgtccactcttatggcaccaacatataagaaactt
gcacctgatgcatataataatcagattgaatatgaacacagagcaccagagtgccgtctg
ggtctgaaggaaggccgtccattctcaggggtcactgcatgtttggacttctgtgctcat
gcccacagagacttgcacaacatgcagaatggcagcacattggtatgcactctcactaga
gaagacaatcgagaatttggaggaaaacctgaggatgagcagcttcacgttctgccttta
tacaaagtctctgacgtggatgagtttgggagtgtggaagctcaggaggagaaaaaacgg
agtggtgccattcaggtactgagttcttttcggcgaaaagtcaggatgttagcagagcca
gtcaagacttgccgacaaaggaaactagaagccaagaaagctgcagctgaaaagctttcc
tccctggagaacagctcaaataaaaatgaaaaggaaaagtcagccccatcacgtacaaaa
caaactgaaaacgcaagccaggctaaacagttggcagaacttttgcgactttcaggacca
gtcatgcagcagtcccagcagccccagcctctacagaagcagccaccacagccccagcag
cagcagagaccccagcagcagcagccacatcaccctcagacagagtctgtcaactcttat
tctgcttctggatccaccaatccatacatgagacggcccaatccagttagtccttatcca
aactcttcacacacttcagatatctatggaagcaccagccctatgaacttctattccacc
tcatctcaagctgcaggttcatatttgaattcttctaatcccatgaacccttaccctggg
cttttgaatcagaatacccaatatccatcatatcaatgcaatggaaacctatcagtggac
aactgctccccatatctgggttcctattctccccagtctcagccgatggatctgtatagg
tatccaagccaagaccctctgtctaagctcagtctaccacccatccatacactttaccag
ccaaggtttggaaatagccagagttttacatctaaatacttaggttatggaaaccaaaat
atgcagggagatggtttcagcagttgtaccattagaccaaatgtacatcatgtagggaaa
ttgcctccttatcccactcatgagatggatggccacttcatgggagccacctctagatta
ccacccaatctgagcaatccaaacatggactataaaaatggtgaacatcattcaccttct
cacataatccataactacagtgcagctccgggcatgttcaacagctctcttcatgccctg
catctccaaaacaaggagaatgacatgctttcccacacagctaatgggttatcaaagatg
cttccagctcttaaccatgatagaactgcttgtgtccaaggaggcttacacaaattaagt
gatgctaatggtcaggaaaagcagccattggcactagtccagggtgtggcttctggtgca
gaggacaacgatgaggtctggtcagacagcgagcagagctttctggatcctgacattggg
ggagtggccgtggctccaactcatgggtcaattctcattgagtgtgcaaagcgtgagctg
catgccacaacccctttaaagaatcccaataggaatcaccccaccaggatctccctcgtc
ttttaccagcataagagcatgaatgagccaaaacatggcttggctctttgggaagccaaa
atggctgaaaaagcccgtgagaaagaggaagagtgtgaaaagtatggcccagactatgtg
cctcagaaatcccatggcaaaaaagtgaaacgggagcctgctgagccacatgaaacttca
gagcccacttacctgcgtttcatcaagtctcttgccgaaaggaccatgtccgtgaccaca
gactccacagtaactacatctccatatgccttcactcgggtcacagggccttacaacaga
tatatatga

Protein Sequence

>54790 : length: 2002
MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY
YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG
ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ
ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI
AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD
ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL
QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS
EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP
QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI
LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM
TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV
HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ
HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK
VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL
VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK
NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ
EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ
QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA
LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCVEQII
EKDEGPFYTHLGAGPNVAAIREIMEERFGQKGKAIRIERVIYTGKEGKSSQGCPIAKWVV
RRSSSEEKLLCLVRERAGHTCEAAVIVILILVWEGIPLSLADKLYSELTETLRKYGTLTN
RRCALNEERTCACQGLDPETCGASFSFGCSWSMYYNGCKFARSKIPRKFKLLGDDPKEEE
KLESHLQNLSTLMAPTYKKLAPDAYNNQIEYEHRAPECRLGLKEGRPFSGVTACLDFCAH
AHRDLHNMQNGSTLVCTLTREDNREFGGKPEDEQLHVLPLYKVSDVDEFGSVEAQEEKKR
SGAIQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTK
QTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSY
SASGSTNPYMRRPNPVSPYPNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNPYPG
LLNQNTQYPSYQCNGNLSVDNCSPYLGSYSPQSQPMDLYRYPSQDPLSKLSLPPIHTLYQ
PRFGNSQSFTSKYLGYGNQNMQGDGFSSCTIRPNVHHVGKLPPYPTHEMDGHFMGATSRL
PPNLSNPNMDYKNGEHHSPSHIIHNYSAAPGMFNSSLHALHLQNKENDMLSHTANGLSKM
LPALNHDRTACVQGGLHKLSDANGQEKQPLALVQGVASGAEDNDEVWSDSEQSFLDPDIG
GVAVAPTHGSILIECAKRELHATTPLKNPNRNHPTRISLVFYQHKSMNEPKHGLALWEAK
MAEKAREKEEECEKYGPDYVPQKSHGKKVKREPAEPHETSEPTYLRFIKSLAERTMSVTT
DSTVTTSPYAFTRVTGPYNRYI



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