Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5519

Name

PPP2R1B

Synonym

PP2A-Abeta|PR65B;protein phosphatase 2, regulatory subunit A, beta;PPP2R1B;protein phosphatase 2, regulatory subunit A, beta

Definition

PP2A, subunit A, PR65-beta isoform|PP2A, subunit A, R1-beta isoform|protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform|protein phosphatase 2, structural/regulatory subunit A, beta|serine/threonine-protein phosphatase 2A 65 kDa regulat

Position

11q23.2

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

13231

TUSON P-value

1

Pathways and Diseases

Pathway

Chagas disease;KEGG PATHWAY;hsa05142

Pathway

Wnt signaling pathway;KEGG PATHWAY;hsa04310

Pathway

DNA Replication;Reactome;REACT:383

Pathway

Opioid Signalling;Reactome;REACT:15295

Pathway

Hemostasis;Reactome;REACT:604

Pathway

Integration of energy metabolism;Reactome;REACT:1505

Pathway

Signaling in Immune system;Reactome;REACT:6900

Pathway

Tight junction;KEGG PATHWAY;hsa04530

Pathway

Signaling by Wnt;Reactome;REACT:11045

Pathway

Long-term depression;KEGG PATHWAY;hsa04730

Pathway

Oocyte meiosis;KEGG PATHWAY;hsa04114

Pathway

TGF-beta signaling pathway;KEGG PATHWAY;hsa04350

Pathway

Hepatitis C;KEGG PATHWAY;hsa05160

Pathway

Signalling by NGF;Reactome;REACT:11061

Pathway

Metabolism of carbohydrates;Reactome;REACT:474

Pathway

FGF signaling pathway;PANTHER;P00021

Pathway

Cell Cycle, Mitotic;Reactome;REACT:152

Disease

Lung cancer;OMIM

External Links

Links to Entrez Gene

5519

Links to all GeneRIF Items

5519

Links to iHOP

5519

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>5519 : length: 1671
atggcgggcgcatcagagctcgggaccggcccaggagcagcgggtggagatggagatgat
tcgctatacccgatcgcggttttaatcgacgagctccgcaatgaagacgtgcagctccga
ctcaacagtattaagaagttatcaacaattgccctagcacttggagtagaaaggacccga
agtgaattgttgccatttcttacagatacaatttatgatgaagatgaggtactattagct
cttgctgagcagctgggaaatttcactggcctagtgggaggtcctgactttgcccactgt
ctgctgcctcctttggaaaatctggcaactgtggaagagactgttgttcgtgacaaggct
gtggagtccctgagacagatctcccaggagcatactcctgttgctctggaagcttatttt
gtacctctggtgaaacgcttagcaagtggggattggttcacctctcgcacatctgcatgt
ggtttgttcagcgtttgctatcccagggcatcaaatgctgttaaagcagaaatcagacag
caattccgttccttgtgctcagatgacacaccaatggtacgacgtgctgctgcttccaaa
ttgggtgaatttgcaaaagttttggaattagacagtgtgaaaagtgaaattgttccactg
ttcactagtctagcttcagatgaacaggattcagtgcgcctccttgctgtggaagcttgt
gtcagtattgcccagttattgtctcaggatgaccttgagactttggtgatgcctacactt
cgacaagcagcagaagataaatcttggcgcgttcgctatatggtggctgacagattttca
gagctccagaaagccatgggtcctaaaatcaccctaaatgacctcatccccgcctttcag
aacctacttaaagactgtgaagctgaagtccgggcagctgctgcccacaaagtaaaagaa
cttggtgagaacttgcccattgaagatagagagaccataattatgaatcaaattctgcct
tatataaagtgtcctgacgttcgtttgaatatcatctccaatttggattgtgtaaatgaa
gtgattggaatccgtcagctctctcagtctctccttcctgccatagtggagctggcagaa
gatgccaaatggagggtccgcctggccatcattgagtatatgccgctgctggcaggccag
ctgggtgtggaattctttgatgaaaagctgaattctttatgtatggcttggctcgtggac
catgtatacgccatccgagaagctgccaccaacaacctcatgaaactagttcagaagttt
ggtacagagtgggcccaaaatactattgttcccaaagtgttagtaatggcaaatgatcct
aattacttgcatagaatgaccactttattctgcattaatgcactgtctgaggcctgtggt
caggaaataactactaagcaaatgctgcccatcgtattaaaaatggcaggagaccaagta
gcaaatgttcgcttcaatgtggccaaatctctacaaaagattggaccaattctagatacc
aatgctttacagggagaagtgaagccagtactacagaagttaggtcaagatgaagacatg
gatgtcaaatactttgcacaggaagctataagtgttcttgcattggcataa

Protein Sequence

>5519 : length: 556
MAGASELGTGPGAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTR
SELLPFLTDTIYDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKA
VESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRASNAVKAEIRQ
QFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEAC
VSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQ
NLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKCPDVRLNIISNLDCVNE
VIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVD
HVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACG
QEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDM
DVKYFAQEAISVLALA



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