| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5519 |
Name | PPP2R1B |
Synonym | PP2A-Abeta|PR65B;protein phosphatase 2, regulatory subunit A, beta;PPP2R1B;protein phosphatase 2, regulatory subunit A, beta |
Definition | PP2A, subunit A, PR65-beta isoform|PP2A, subunit A, R1-beta isoform|protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform|protein phosphatase 2, structural/regulatory subunit A, beta|serine/threonine-protein phosphatase 2A 65 kDa regulat |
Position | 11q23.2 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 13231 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Chagas disease;KEGG PATHWAY;hsa05142 |
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | DNA Replication;Reactome;REACT:383 |
Pathway | Opioid Signalling;Reactome;REACT:15295 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Integration of energy metabolism;Reactome;REACT:1505 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Tight junction;KEGG PATHWAY;hsa04530 |
Pathway | Signaling by Wnt;Reactome;REACT:11045 |
Pathway | Long-term depression;KEGG PATHWAY;hsa04730 |
Pathway | Oocyte meiosis;KEGG PATHWAY;hsa04114 |
Pathway | TGF-beta signaling pathway;KEGG PATHWAY;hsa04350 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Metabolism of carbohydrates;Reactome;REACT:474 |
Pathway | FGF signaling pathway;PANTHER;P00021 |
Pathway | Cell Cycle, Mitotic;Reactome;REACT:152 |
Disease | Lung cancer;OMIM |
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External Links |
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Links to Entrez Gene | 5519 |
Links to all GeneRIF Items | 5519 |
Links to iHOP | 5519 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5519 : length: 1671 atggcgggcgcatcagagctcgggaccggcccaggagcagcgggtggagatggagatgat tcgctatacccgatcgcggttttaatcgacgagctccgcaatgaagacgtgcagctccga ctcaacagtattaagaagttatcaacaattgccctagcacttggagtagaaaggacccga agtgaattgttgccatttcttacagatacaatttatgatgaagatgaggtactattagct cttgctgagcagctgggaaatttcactggcctagtgggaggtcctgactttgcccactgt ctgctgcctcctttggaaaatctggcaactgtggaagagactgttgttcgtgacaaggct gtggagtccctgagacagatctcccaggagcatactcctgttgctctggaagcttatttt gtacctctggtgaaacgcttagcaagtggggattggttcacctctcgcacatctgcatgt ggtttgttcagcgtttgctatcccagggcatcaaatgctgttaaagcagaaatcagacag caattccgttccttgtgctcagatgacacaccaatggtacgacgtgctgctgcttccaaa ttgggtgaatttgcaaaagttttggaattagacagtgtgaaaagtgaaattgttccactg ttcactagtctagcttcagatgaacaggattcagtgcgcctccttgctgtggaagcttgt gtcagtattgcccagttattgtctcaggatgaccttgagactttggtgatgcctacactt cgacaagcagcagaagataaatcttggcgcgttcgctatatggtggctgacagattttca gagctccagaaagccatgggtcctaaaatcaccctaaatgacctcatccccgcctttcag aacctacttaaagactgtgaagctgaagtccgggcagctgctgcccacaaagtaaaagaa cttggtgagaacttgcccattgaagatagagagaccataattatgaatcaaattctgcct tatataaagtgtcctgacgttcgtttgaatatcatctccaatttggattgtgtaaatgaa gtgattggaatccgtcagctctctcagtctctccttcctgccatagtggagctggcagaa gatgccaaatggagggtccgcctggccatcattgagtatatgccgctgctggcaggccag ctgggtgtggaattctttgatgaaaagctgaattctttatgtatggcttggctcgtggac catgtatacgccatccgagaagctgccaccaacaacctcatgaaactagttcagaagttt ggtacagagtgggcccaaaatactattgttcccaaagtgttagtaatggcaaatgatcct aattacttgcatagaatgaccactttattctgcattaatgcactgtctgaggcctgtggt caggaaataactactaagcaaatgctgcccatcgtattaaaaatggcaggagaccaagta gcaaatgttcgcttcaatgtggccaaatctctacaaaagattggaccaattctagatacc aatgctttacagggagaagtgaagccagtactacagaagttaggtcaagatgaagacatg gatgtcaaatactttgcacaggaagctataagtgttcttgcattggcataa |
Protein Sequence |
>5519 : length: 556 MAGASELGTGPGAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTR SELLPFLTDTIYDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKA VESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRASNAVKAEIRQ QFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEAC VSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQ NLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKCPDVRLNIISNLDCVNE VIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVD HVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACG QEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDM DVKYFAQEAISVLALA |