Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5524

Name

PPP2R4

Synonym

PP2A|PR53|PTPA;protein phosphatase 2A activator, regulatory subunit 4;PPP2R4;protein phosphatase 2A activator, regulatory subunit 4

Definition

PP2A phosphatase activator|PP2A subunit B' isoform PR53|phosphotyrosyl phosphatase activator|protein phosphatase 2A, regulatory subunit B' (PR 53)|serine/threonine-protein phosphatase 2A activator|serine/threonine-protein phosphatase 2A regulatory subunit

Position

9q34

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

13238

TUSON P-value

1

Pathways and Diseases

Pathway

Validated targets of C-MYC transcriptional repression;PID Curated;200171

Pathway

p53 pathway;PID Curated;200175

External Links

Links to Entrez Gene

5524

Links to all GeneRIF Items

5524

Links to iHOP

5524

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>5524 : length: 867
atgggcaaatggaagcgttctcaggcatacgctgactacatcggattcatccttaccctc
aacgaaggtgtgaaggggaagaagctgaccttcgagtacagagtctccgaggccattgag
aaactagtcgctcttctcaacacgctggacaggtggattgatgagactcctccagtggac
cagccctctcggtttgggaataaggcatacaggacctggtatgccaaacttgatgaggaa
gcagaaaacttggtggccacagtggtccctacccatctggcagctgctgtgcctgaggtg
gctgtttacctaaaggagtcagtggggaactccacgcgcattgactacggcacagggcat
gaggcagccttcgctgctttcctctgctgtctctgcaagattggggtgctccgggtggat
gaccaaatagctattgtcttcaaggtgttcaatcggtaccttgaggttatgcggaaactc
cagaaaacatacaggatggagccagccggcagccagggagtgtggggtctggatgacttc
cagtttctgcccttcatctggggcagttcgcagctgatagaccacccatacctggagccc
agacactttgtggatgagaaggccgtgaatgagaaccacaaggactacatgttcctggag
tgtatcctgtttattaccgagatgaagactggcccatttgcagagcactccaaccagctg
tggaacatcagcgccgtcccttcctggtccaaagtgaaccagggtctcatccgcatgtat
aaggccgagtgcctggagaagttccctgtgatccagcacttcaagttcgggagcctgctg
cccatccatcctgtcacgtcgggctag

Protein Sequence

>5524 : length: 288
MGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVD
QPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGH
EAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDF
QFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQL
WNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG



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