| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5533 |
Name | PPP3CC |
Synonym | CALNA3|CNA3|PP2Bgamma;protein phosphatase 3, catalytic subunit, gamma isozyme;PPP3CC;protein phosphatase 3, catalytic subunit, gamma isozyme |
Definition | CAM-PRP catalytic subunit|calcineurin, testis-specific catalytic subunit|calmodulin-dependent calcineurin A subunit gamma isoform|protein phosphatase 2B, catalytic subunit, gamma isoform|protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isofor |
Position | 8p21.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 262 |
TUSON P-value | 0.001859349 |
|
Pathways and Diseases |
|
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | B cell receptor signaling pathway;KEGG PATHWAY;hsa04662 |
Pathway | signaling pathway from g-protein families;PID BioCarta;100153 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | effects of calcineurin in keratinocyte differentiation;PID BioCarta;100222 |
Pathway | Alzheimer's disease;KEGG PATHWAY;hsa05010 |
Pathway | role of mef2d in t-cell apoptosis;PID BioCarta;100109 |
Pathway | t cell receptor signaling pathway;PID BioCarta;100022 |
Pathway | regulation of pgc-1a;PID BioCarta;100075 |
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | Opioid Signalling;Reactome;REACT:15295 |
Pathway | Apoptosis;KEGG PATHWAY;hsa04210 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
Pathway | T cell activation;PANTHER;P00053 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Amyotrophic lateral sclerosis (ALS);KEGG PATHWAY;hsa05014 |
Pathway | nitric oxide signaling pathway;PID BioCarta;100092 |
Pathway | VEGF signaling pathway;KEGG PATHWAY;hsa04370 |
Pathway | Long-term potentiation;KEGG PATHWAY;hsa04720 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Calcium signaling pathway;KEGG PATHWAY;hsa04020 |
Pathway | bcr signaling pathway;PID BioCarta;100227 |
Pathway | fmlp induced chemokine gene expression in hmc-1 cells;PID BioCarta;100162 |
Pathway | nfat and hypertrophy of the heart ;PID BioCarta;100098 |
Pathway | Oocyte meiosis;KEGG PATHWAY;hsa04114 |
Pathway | endocytotic role of ndk phosphins and dynamin;PID BioCarta;100099 |
Pathway | Natural killer cell mediated cytotoxicity;KEGG PATHWAY;hsa04650 |
Disease | HIV-1 control;NHGRI |
Disease | PSYCH;GAD |
Disease | schizophrenia;GAD |
|
External Links |
|
Links to Entrez Gene | 5533 |
Links to all GeneRIF Items | 5533 |
Links to iHOP | 5533 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5533 : length: 1539 atgtccgggaggcgcttccacctctccaccaccgaccgcgtcatcaaagctgtccccttt cctccaacccaacggcttactttcaaggaagtatttgagaatgggaaacctaaagttgat gttttaaaaaaccatttggtaaaggaaggacgactggaagaggaagtagccttaaagata atcaatgatggggctgccatcctgaggcaagagaagactatgatagaagtagatgctcca atcacagtatgtggtgatattcatggacaattctttgacctaatgaagttatttgaagtt ggaggatcacctagtaacacacgctacctctttctgggtgactatgtggacagaggctat ttcagtatagagtgtgtgctgtatttatggagtttaaagattaatcatcccaaaacattg tttctgcttcggggaaatcatgaatgcaggcatcttacagactatttcaccttcaaacag gaatgtcgaatcaaatattcggaacaggtgtatgatgcctgtatggagacatttgactgt cttcctcttgctgccctcttaaaccagcagtttctctgtgtacatggaggaatgtcacct gaaattacttctttagatgacattaggaaattagacaggtttacggaacctcccgccttt ggacctgtgtgtgacctgctttggtctgatccctcagaggattatggcaatgagaagacc ttggagcactatacccacaacactgtccgagggtgctcttatttctacagttaccctgca gtttgtgaatttttgcagaacaataatttactatcaattatcagagcccatgaagcccaa gatgctgggtatcgaatgtacaggaagagccaagccacaggctttccatcacttattaca attttctctgcccccaattacctagatgtctataacaataaagctgctgtgttgaaatat gaaaacaatgtcatgaatatcaggcagtttaactgttctccacacccctactggcttcca aactttatggatgttttcacatggtctttgccttttgttggggaaaaagtcacagagatg ctggtaaatgtgctcaacatatgctctgatgacgaactgatttctgatgatgaagcagaa ggaagcactacagttcgtaaggagatcatcaggaataagatcagagccattgggaagatg gcacgggtcttttcaattcttcggcaagaaagtgagagtgtgctgactctcaagggcctg actcccacaggcacactccctctgggcgtcctctcaggaggcaagcagactatcgagaca gccacagtagaagcggtagaggcccgggaagccatcagagggttctcgcttcagcacaag atccggagttttgaagaagcgcgaggtctggaccgaattaatgagcgaatgccaccccga aaggatagcatacacgctggtgggccaatgaaatctgtaacctcagcacactcacatgct gcgcacaggagcgaccaagggaagaaagcccattcatga |
Protein Sequence |
>5533 : length: 512 MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKI INDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY FSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDC LPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKT LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLIT IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM LVNVLNICSDDELISDDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGL TPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPR KDSIHAGGPMKSVTSAHSHAAHRSDQGKKAHS |