| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5625 |
Name | PRODH |
Synonym | HSPOX2|PIG6|POX|PRODH1|PRODH2|TP53I6;proline dehydrogenase (oxidase) 1;PRODH;proline dehydrogenase (oxidase) 1 |
Definition | p53-induced gene 6 protein|proline dehydrogenase 1, mitochondrial|proline oxidase 2|proline oxidase, mitochondrial|tumor protein p53 inducible protein 6 |
Position | 22q11.21 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 13373 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | citrulline biosynthesis;BioCyc;CITRULBIO-PWY |
Pathway | proline degradation;BioCyc;PROUT-PWY |
Pathway | Arginine and proline metabolism;KEGG PATHWAY;hsa00330 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Metabolism of amino acids and derivatives;Reactome;REACT:13 |
Pathway | superpathway of citrulline metabolism;BioCyc;PWY-5004 |
Pathway | Proline catabolism;PID Reactome;500951 |
Pathway | Huntington disease;PANTHER;P00029 |
Disease | Hyperprolinemia;KEGG DISEASE;H00190 |
Disease | PSYCH;GAD |
Disease | Genetic disorders;KEGG DISEASE |
Disease | Hyperprolinemia, type I;OMIM |
Disease | Inherited disorders of amino acid metabolism;KEGG DISEASE |
Disease | schizophrenia;GAD |
Disease | CATCH 22 syndrome;GAD |
Disease | Schizophrenia, susceptibility to, 4;OMIM |
|
External Links |
|
Links to Entrez Gene | 5625 |
Links to all GeneRIF Items | 5625 |
Links to iHOP | 5625 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5625 : length: 1479 atgaagatgaccttctatgggcattttgtagccggggaggaccaggagtccatccagccc ctgcttcggcactacagggccttcggtgtcagcgccatcctggactatggagtggaggag gacctgagccccgaggaggcagagcacaaggagatggagtcctgcacctcagctgcggag agggatggcagtggcacgaataagcgggacaagcaataccaggcccaccgggccttcggg gaccgcaggaatggtgtcatcagtgcccgcacctacttctacgccaatgaggccaagtgc gacagccacatggagacattcttgcgctgcatcgaagcctcaggtagagtcagcgatgac ggcttcatagccattaagctcacagcactggggagaccccagtttctgctgcagttctca gaggtgctggccaagtggaggtgcttctttcaccaaatggctgtggagcaagggcaggcg ggcctggctgccatggacaccaagctggaggtggcggtgctgcaggaaagtgtcgcaaag ttgggcatcgcatccagggctgagattgaggactggttcacggcagagaccctgggagtg tctggcaccatggacctgctggactggagcagcctcatcgacagcaggaccaagctgtcc aagcacttggtagtccccaacgcacagacaggacagctggagcccctgctgtcccggttc actgaggaggaggagctacagatgaccaggatgctacagcggatggatgtcctggccaag aaagccacagagatgggcgtgcggctgatggtggatgccgagcagacctacttccagccg gccatcagccgcctgacgctggagatgcagcggaagttcaatgtggagaagccgctcatc ttcaacacataccagtgctacctcaaggatgcctatgacaatgtgaccctggacgtggag ctggctcgccgtgagggctggtgttttggggccaagctggtgcggggcgcatacctggcc caggagcgagcccgtgcggcagagatcggctatgaggaccccatcaaccccacgtacgag gccaccaacgccatgtaccacaggtgcctggactacgtgttggaggagctgaagcacaac gccaaggccaaggtgatggtggcctcccacaatgaggacacagtgcgctttgcactgcgc aggatggaggagctgggcctgcatcctgctgaccaccaggtgtactttggacagctgcta ggcatgtgtgaccagatcagcttcccgctgggccaggccggctaccccgtgtacaagtac gtgccctatggccccgtgatggaggtgctgccctacttgtcccgccgtgccctggagaac agcagcctcatgaagggcacccatcgggagcggcagctgctgtggctggagctcttgagg cggctccgaactggcaacctcttccatcgccctgcctag |
Protein Sequence |
>5625 : length: 492 MKMTFYGHFVAGEDQESIQPLLRHYRAFGVSAILDYGVEEDLSPEEAEHKEMESCTSAAE RDGSGTNKRDKQYQAHRAFGDRRNGVISARTYFYANEAKCDSHMETFLRCIEASGRVSDD GFIAIKLTALGRPQFLLQFSEVLAKWRCFFHQMAVEQGQAGLAAMDTKLEVAVLQESVAK LGIASRAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQLEPLLSRF TEEEELQMTRMLQRMDVLAKKATEMGVRLMVDAEQTYFQPAISRLTLEMQRKFNVEKPLI FNTYQCYLKDAYDNVTLDVELARREGWCFGAKLVRGAYLAQERARAAEIGYEDPINPTYE ATNAMYHRCLDYVLEELKHNAKAKVMVASHNEDTVRFALRRMEELGLHPADHQVYFGQLL GMCDQISFPLGQAGYPVYKYVPYGPVMEVLPYLSRRALENSSLMKGTHRERQLLWLELLR RLRTGNLFHRPA |