| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5783 |
Name | PTPN13 |
Synonym | FAP-1|PNP1|PTP-BAS|PTP-BL|PTP1E|PTPL1|PTPLE|hPTP1E;protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase);PTPN13;protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
Definition | fas-associated protein-tyrosine phosphatase 1|hPTPE1|protein-tyrosine phosphatase 1E|protein-tyrosine phosphatase PTPL1|tyrosine-protein phosphatase non-receptor type 13 |
Position | 4q21.3 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 13593 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | fas signaling pathway (cd95);PID BioCarta;100167 |
Pathway | Ephrin B reverse signaling;PID Curated;200173 |
Pathway | Fc-epsilon receptor I signaling in mast cells;PID Curated;200003 |
Disease | Primary biliary cirrhosis;FunDO |
Disease | Breast cancer;FunDO |
Disease | Neoplasm metastasis;FunDO |
Disease | Rheumatoid arthritis;FunDO |
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External Links |
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Links to Entrez Gene | 5783 |
Links to all GeneRIF Items | 5783 |
Links to iHOP | 5783 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5783 : length: 7401 atgcacgtgtcactagctgaggccctggaggttcggggtggaccacttcaggaggaagaa atatgggctgtattaaatcaaagtgctgaaagtctccaagaattattcagaaaagtaagc ctagctgatcctgctgcccttggcttcatcatttctccatggtctctgctgttgctgcca tctggtagtgtgtcatttacagatgaaaatatttccaatcaggatcttcgagcattcact gcaccagaggttcttcaaaatcagtcactaacttctctctcagatgttgaaaagatccac atttattctcttggaatgacactgtattggggggctgattatgaagtgcctcagagccaa cctattaagcttggagatcatctcaacagcatactgcttggaatgtgtgaggatgttatt tacgctcgagtttctgttcggactgtgctggatgcttgcagtgcccacattaggaatagc aattgtgcaccctcattttcctacgtgaaacacttggtaaaactggttctgggaaatctt tctgggacagatcagctttcctgtaacagtgaacaaaagcctgatcgaagccaggctatt cgagatcgattgcgaggaaaaggattaccaacaggaagaagctctacttctgatgtacta gacatacaaaagcctccactctctcatcagacctttcttaacaaagggcttagtaaatct atgggatttctgtccatcaaagatacacaagatgagaattatttcaaggacattttatca gataattctggacgtgaagattctgaaaatacattctccccttaccagttcaaaactagt ggcccagaaaaaaaacccatccctggcattgatgtgctttctaagaagaagatctgggct tcatccatggacttgctttgtacagctgacagagacttctcttcaggagagactgccaca tatcgtcgttgtcaccctgaggcagtaacagtgcggacttcaactactcctagaaaaaag gaggcaagatactcagatggaagtatagccttggatatctttggccctcagaaaatggat ccaatatatcacactcgagaattgcccacctcctcagcaatatcaagtgctttggaccga atccgagagagacaaaagaaacttcaggttctgagggaagccatgaatgtagaagaacca gttcgaagatacaaaacttatcatggtgatgtctttagtacctccagtgaaagtccatct attatttcctctgaatcagatttcagacaagtgagaagaagtgaagcctcaaagaggttt gaatccagcagtggtctcccaggggtagatgaaaccttaagtcaaggccagtcacagaga ccgagcagacaatatgaaacaccctttgaaggcaacttaattaatcaagagatcatgcta aaacggcaagaggaagaactgatgcagctacaagccaaaatggcccttagacagtctcgg ttgagcctatatccaggagacacaatcaaagcgtccatgcttgacatcaccagggatccg ttaagagaaattgccctagaaacagccatgactcaaagaaaactgaggaatttctttggc cctgagtttgtgaaaatgacaattgaaccatttatatctttggatttgccacggtctatt cttactaagaaagggaagaatgaggataaccgaaggaaagtaaacataatgcttctgaac gggcaaagactggaactgacctgtgataccaaaactatatgtaaagatgtgtttgatatg gttgtggcacatattggcttagtagagcatcatttgtttgctttagctaccctcaaagat aatgaatatttctttgttgatcctgacttaaaattaaccaaagtggccccagagggatgg aaagaagaaccaaagaaaaagaccaaagccactgttaattttactttgtttttcagaatt aaattttttatggatgatgttagtctaatacaacatactctgacgtgtcatcagtattac cttcagcttcgaaaagatattttggaggaaaggatgcactgtgatgatgagacttcctta ttgctggcatccttggctctccaggctgagtatggagattatcaaccagaggttcatggt gtgtcttactttagaatggagcactatttgcccgccagagtgatggagaaacttgattta tcctatatcaaagaagagttacccaaattgcataatacctatgtgggagcttctgaaaaa gagacagagttagaatttttaaaggtctgccaaagactgacagaatatggagttcatttt caccgagtgcaccctgagaagaagtcacaaacaggaatattgcttggagtctgttctaaa ggtgtccttgtgtttgaagttcacaatggagtgcgcacattggtccttcgctttccatgg agggaaaccaagaaaatatctttttctaaaaagaaaatcacattgcaaaatacatcagat ggaataaaacatggcttccagacagacaacagtaagatatgccagtacctgctgcacctc tgctcttaccagcataagttccagctacagatgagagcaagacagagcaaccaagatgcc caagatattgagagagcttcgtttaggagcctgaatctccaagcagagtctgttagagga tttaatatgggacgagcaatcagcactggcagtctggccagcagcaccctcaacaaactt gctgttcgacctttatcagttcaagctgagattctgaagaggctatcctgctcagagctg tcgctttaccagccattgcaaaacagttcaaaagagaagaatgacaaagcttcatgggag gaaaagcctagagagatgagtaaatcataccatgatctcagtcaggcctctctctatcca catcggaaaaatgtcattgttaacatggaacccccaccacaaaccgttgcagagttggtg ggaaaaccttctcaccagatgtcaagatctgatgcagaatctttggcaggagtgacaaaa cttaataattcaaagtctgttgcgagtttaaatagaagtcctgaaaggaggaaacatgaa tcagactcctcatccattgaagaccctgggcaagcatatgttctagatgtgctacacaaa agatggagcatagtatcttcaccagaaagggagatcaccttagtgaacctgaaaaaagat gcaaagtatggcttgggatttcaaattattggtggggagaagatgggaagactggaccta ggcatatttatcagttcagttgcccctggaggaccagctgacttggatggatgcttgaag ccaggagaccgtttgatatctgtgaatagtgtgagtctggagggagtcagccaccatgct gcaattgaaattttgcaaaatgcacctgaagatgtgacacttgttatctctcagccaaaa gaaaagatatccaaagtgccttctactcctgtgcatctcaccaatgagatgaaaaactac atgaagaaatcttcctacatgcaagacagtgctatagattcttcttccaaggatcaccac tggtcacgtggtaccctgaggcacatctcggagaactcctttgggccatctgggggcctg cgggaaggaagcctgagttctcaagattccaggactgagagtgccagcttgtctcaaagc caggtcaatggtttctttgccagccatttaggtgaccaaacctggcaggaatcacagcat ggcagcccttccccatctgtaatatccaaagccaccgagaaagagactttcactgatagt aaccaaagcaaaactaaaaagccaggcatttctgatgtaactgattactcagaccgtgga gattcagacatggatgaagccacttactccagcagtcaggatcatcaaacaccaaaacag gaatcttcctcttcagtgaatacatccaacaagatgaattttaaaactttttcttcatca cctcctaagcctggagatatctttgaggttgaactggctaaaaatgataacagcttgggg ataagtgtcacgggaggtgtgaatacgagtgtcagacatggtggcatttatgtgaaagct gttattccccagggagcagcagagtctgatggtagaattcacaaaggtgatcgcgtccta gctgtcaatggagttagtctagaaggagccacccataagcaagctgtggaaacactgaga aatacaggacaggtggttcatctgttattagaaaagggacaatctccaacatctaaagaa catgtcccggtaaccccacagtgtaccctttcagatcagaatgcccaaggtcaaggccca gaaaaagtgaagaaaacaactcaggtcaaagactacagctttgtcactgaagaaaataca tttgaggtaaaattatttaaaaatagctcaggtctaggattcagtttttctcgagaagat aatcttataccggagcaaattaatgccagcatagtaagggttaaaaagctctttcctgga cagccagcagcagaaagtggaaaaattgatgtaggagatgttatcttgaaagtgaatgga gcctctttgaaaggactatctcagcaggaagtcatatctgctctcaggggaactgctcca gaagtattcttgcttctctgcagacctccacctggtgtgctaccggaaattgatactgcg cttttgaccccacttcagtctccagcacaagtacttccaaacagcagtaaagactcttct cagccatcatgtgtggagcaaagcaccagctcagatgaaaatgaaatgtcagacaaaagc aaaaaacagtgcaagtccccatccagaagagacagttacagtgacagcagtgggagtgga gaagatgacttagtgacagctccagcaaacatatcaaattcgacctggagttcagctttg catcagactctaagcaacatggtatcacaggcacagagtcatcatgaagcacccaagagt caagaagataccatttgtaccatgttttactatcctcagaaaattcccaataaaccagag tttgaggacagtaatccttcccctctaccaccggatatggctcctgggcagagttatcaa ccccaatcagaatctgcttcctctagttcgatggataagtatcatatacatcacatttct gaaccaactagacaagaaaactggacacctttgaaaaatgacttggaaaatcaccttgaa gactttgaactggaagtagaactcctcattaccctaattaaatcagaaaaaggaagcctg ggttttacagtaaccaaaggcaatcagagaattggttgttatgttcatgatgtcatacag gatccagccaaaagtgatggaaggctaaaacctggggaccggctcataaaggttaatgat acagatgttactaatatgactcatacagatgcagttaatctgctccgggctgcatccaaa acagtcagattagttattggacgagttctagaattacccagaataccaatgttgcctcat ttgctaccggacataacactaacgtgcaacaaagaggagttgggtttttccttatgtgga ggtcatgacagcctttatcaagtggtatatattagtgatattaatccaaggtccgtcgca gccattgagggtaatctccagctattagatgtcatccattatgtgaacggagtcagcaca caaggaatgaccttggaggaagttaacagagcattagacatgtcacttccttcattggta ttgaaagcaacaagaaatgatcttccagtggtccccagctcaaagaggtctgctgtttca gctccaaagtcaaccaaaggcaatggttcctacagtgtggggtcttgcagccagcctgcc ctcactcctaatgattcattctccacggttgctggggaagaaataaatgaaatatcgtac cccaaaggaaaatgttctacttatcagataaagggatcaccaaacttgactctgcccaaa gaatcttatatacaagaagatgacatttatgatgattcccaagaagctgaagttatccag tctctgctggatgttgtggatgaggaagcccagaatcttttaaacgaaaataatgcagca ggatactcctgtggtccaggtacattaaagatgaatgggaagttatcagaagagagaaca gaagatacagactgcgatggttcacctttacctgagtattttactgaggccaccaaaatg aatggctgtgaagaatattgtgaagaaaaagtaaaaagtgaaagcttaattcagaagcca caagaaaagaagactgatgatgatgaaataacatggggaaatgatgagttgccaatagag agaacaaaccatgaagattctgataaagatcattcctttctgacaaacgatgagctcgct gtactccctgtcgtcaaagtgcttccctctggtaaatacacgggtgccaacttaaaatca gtcattcgagtcctgcggggtttgctagatcaaggaattccttctaaggagctggagaat cttcaagaattaaaacctttggatcagtgtctaattgggcaaactaaggaaaacagaagg aagaacagatataaaaatatacttccctatgatgctacaagagtgcctcttggagatgaa ggtggctatatcaatgccagcttcattaagataccagttgggaaagaagagttcgtttac attgcctgccaaggaccactgcctacaactgttggagacttctggcagatgatttgggag caaaaatccacagtgatagccatgatgactcaagaagtagaaggagaaaaaatcaaatgc cagcgctattggcccaacatcctaggcaaaacaacaatggtcagcaacagacttcgactg gctcttgtgagaatgcagcagctgaagggctttgtggtgagggcaatgacccttgaagat attcagaccagagaggtgcgccatatttctcatctgaatttcactgcctggccagaccat gatacaccttctcaaccagatgatctgcttacttttatctcctacatgagacacatccac agatcaggcccaatcattacgcactgcagtgctggcattggacgttcagggaccctgatt tgcatagatgtggttctgggattaatcagtcaggatcttgattttgacatctctgatttg gtgcgctgcatgagactacaaagacacggaatggttcagacagaggatcaatatattttc tgctatcaagtcatcctttatgtcctgacacgtcttcaagcagaagaagagcaaaaacag cagcctcagcttctgaagtga |
Protein Sequence |
>5783 : length: 2466 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKD AKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHA AIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSAIDSSSKDHH WSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDQTWQESQH GSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQTPKQ ESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKA VIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKE HVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGFSFSRED NLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAP EVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKS KKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEAPKS QEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIHHIS EPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQ DPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPRIPMLPH LLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNGVST QGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPA LTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQ SLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTEDTDCDGSPLPEYFTEATKM NGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELA VLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRR KNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWE QKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLED IQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLI CIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQ QPQLLK |