Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5796

Name

PTPRK

Synonym

R-PTP-kappa;protein tyrosine phosphatase, receptor type, K;PTPRK;protein tyrosine phosphatase, receptor type, K

Definition

dJ480J14.2.1 (protein tyrosine phosphatase, receptor type, K (R-PTP-KAPPA, protein tyrosine phosphatase kappa , protein tyrosine phosphatase kappa|protein-tyrosine phosphatase kappa|protein-tyrosine phosphatase, receptor type, kappa|receptor-type tyrosine

Position

6q22.2-q22.3

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

204

TUSON P-value

0.000660423

Pathways and Diseases

Pathway

Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039

Disease

IMMUNE;GAD

Disease

Celiac Disease;GAD

Disease

Cancer;FunDO

Disease

Celiac disease;NHGRI

External Links

Links to Entrez Gene

5796

Links to all GeneRIF Items

5796

Links to iHOP

5796

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>5796 : length: 4341
atggatacgactgcggcggcggcgctgcctgcttttgtggcgctcttgctcctctctcct
tggcctctcctgggatcggcccaaggccagttctccgcaggtggctgtacttttgatgat
ggtccaggggcctgtgattaccaccaggatctgtatgatgactttgaatgggtgcatgtt
agtgctcaagagcctcattatctaccacccgagatgccccaaggttcctatatgatagtg
gactcttcagatcacgaccctggagaaaaagccagacttcagctgcctacaatgaaggag
aacgacactcactgcattgatttcagttacctattatatagccagaaaggactgaatcct
ggcactttgaacatattagttagggtgaataaaggacctcttgccaatccaatttggaat
gtgactggattcacgggtagagattggcttcgggctgagctagcagtgagcaccttttgg
cccaatgaatatcaggtaatatttgaagctgaagtctcaggagggagaagtggttatatt
gccattgatgacatccaagtactgagttatccttgtgataaatctcctcatttcctccgt
ctaggggatgtagaggtgaatgcagggcaaaacgctacatttcagtgcattgccacaggg
agagatgctgtgcataacaagttatggctccagagacgaaatggagaagatataccagta
gcccagactaagaacatcaatcatagaaggtttgccgcttccttcagattgcaagaagtg
acaaaaactgaccaggatttgtatcgctgtgtaactcagtcagaacgaggttccggtgtg
tccaattttgctcaacttattgtgagagaaccgccaagacccattgctcctcctcagctt
cttggtgttgggcctacatatttgctgatccaactaaatgccaactcgatcattggcgat
ggtcctatcatcctgaaagaagtagagtaccgaatgacatcaggatcctggacagaaacc
catgcagtcaatgctccaacttacaaattatggcatttagatccagataccgaatatgag
atccgagttctacttacaagacctggtgaaggtggaacggggctcccaggacctccacta
atcaccagaacaaaatgtgcagaacctatgagaaccccaaagacattaaagattgctgaa
atacaggcaagacggattgctgtggactgggaatccttgggttacaacattacgcgttgc
cacacttttaatgtcactatctgctaccattacttccgtggtcacaacgagagcaaggca
gactgtttggacatggaccccaaagcccctcagcatgttgtgaaccatctgccaccttat
acaaatgtcagcctcaagatgatcctaaccaatccagagggaaggaaggagagtgaagag
acaattattcaaactgatgaagatgtgcctggtcccgtaccagtaaaatctcttcaagga
acatcctttgaaaataagatcttcttgaactggaaagaacctttggatccaaatggaatc
atcactcaatatgagatcagctatagcagtataagatcatttgatcctgcagttccagtg
gctggacctccccagactgtatcaaatttatggaacagtacacaccatgtctttatgcat
ctccaccctggaaccacgtaccagtttttcataagagccagcacggtcaaaggctttggt
ccagccacagccatcaatgtcaccaccaatatctcagctccaactttacctgactatgaa
ggagttgatgcctctctcaatgaaactgccaccacaataactgtattgttgagaccagca
caagccaaaggtgctcctatcagtgcttatcagattgttgtggaagaactgcacccacac
cgaaccaagagagaagccggagccatggaatgctaccaggttcctgtcacataccaaaat
gccatgagtgggggtgcaccgtattactttgctgcagaactccccccgggaaacctacct
gagcctgccccgttcactgtgggtgacaatcggacctaccaaggcttttggaaccctcct
ttggctccgcgcaaaggatacaacatctatttccaggcgatgagcagtgtggagaaggaa
actaaaacccagtgcgtacgcattgctacaaaagcagcagcaacagaagaaccagaagtg
atcccagatcccgccaagcagacagacagagtggtgaaaatagcaggaattagtgctgga
attttggtgttcatcctccttctcctagttgtcatattaattgtaaaaaagagcaaactt
gctaaaaaacgcaaagatgccatggggaatacccggcaggagatgactcacatggtgaat
gcaatggatcgaagttatgctgatcagagcactctgcatgcagaagatcctctttccatc
accttcatggaccaacataactttagtccaagatatgagaaccacagtgctacagcagag
tccagtcgccttctagacgtacctcgctacctctgtgaggggacggaatccccttaccag
acaggacagctgcatccagccatcagggtagctgatttactgcagcacattaatctcatg
aagacatcagacagctatgggttcaaagaggaatatgagagcttttttgaaggacagtca
gcatcttgggatgtagctaaaaaagatcaaaatagagcaaaaaaccgatatggaaacatt
atagcatatgatcactccagagtgattttgcaacccgtagaggatgatccttcctcagat
tatattaatgccaactatattgatatttggctgtacagggatggctaccagagaccaagt
cattacattgcaacccaaggtcccgttcatgaaacagtgtatgatttctggaggatgatt
tggcaagaacaatctgcttgcattgtgatggttacaaatttagttgaggttggccgggtt
aaatgctataaatattggcctgatgatactgaagtttatggtgacttcaaagtaacgtgt
gtagaaatggaaccacttgctgaatatgtagttaggacattcaccctggaaaggaggggg
tacaatgaaatccgtgaagttaaacagttccatttcacgggctggcctgaccatggagtg
ccctaccatgctacagggctgctttcctttatccggcgagtcaagttatcaaaccctccc
agtgctggccccatcgttgtacattgcagtgctggtgctggacgaactggctgctacatt
gtgattgacatcatgctagacatggctgaaagagagggtgttgttgatatttacaattgt
gtcaaagccttaagatctcggcgtattaatatggtccagacagaggaacagtacattttt
attcatgatgccattttagaagcctgcttatgtggagaaactgccatacctgtctgtgaa
tttaaagctgcatattttgatatgattagaatagactcccagactaactcttcacatctc
aaggatgaatttcagactctgaattcagtcacccctcgactacaagctgaagactgcagt
atagcgtgcctgccaaggaaccatgacaagaaccgtttcatggacatgctgccacctgac
agatgtctgccttttttaattacaattgatggggagagcagtaactacatcaatgctgct
cttatggacagctacaggcaaccagctgctttcatcgtcacacaataccctctgccaaac
actgtaaaagacttctggagattagtgtatgattatggctgtacctccattgtgatgtta
aacgaagtcgacttgtcccagggctgccctcagtactggccagaggaagggatgctacga
tatggccccatccaagtggaatgtatgtcttgttcaatggactgtgatgtgatcaaccgg
atttttaggatatgcaatctaacaagaccacaggaaggttatctgatggtgcaacagttt
cagtacctaggatgggcttctcatcgagaagtgcctggatccaaaaggtcattcttgaaa
ctgatacttcaggtggaaaagtggcaggaggaatgcgaggaaggggaaggccggacgatt
atccactgcctaaatggtggcgggcgaagtggcatgttctgtgctataggcatcgttgtt
gaaatggtgaaacggcaaaatgttgtcgatgttttccatgcagtaaagacactgaggaac
agcaagccaaacatggtggaagccccggagcaataccgtttctgctatgatgtagctttg
gagtacctggaatcatcttag

Protein Sequence

>5796 : length: 1446
MDTTAAAALPAFVALLLLSPWPLLGSAQGQFSAGGCTFDDGPGACDYHQDLYDDFEWVHV
SAQEPHYLPPEMPQGSYMIVDSSDHDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLNP
GTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYI
AIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATFQCIATGRDAVHNKLWLQRRNGEDIPV
AQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIAPPQL
LGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYE
IRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRC
HTFNVTICYHYFRGHNESKADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEE
TIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPLDPNGIITQYEISYSSIRSFDPAVPV
AGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISAPTLPDYE
GVDASLNETATTITVLLRPAQAKGAPISAYQIVVEELHPHRTKREAGAMECYQVPVTYQN
AMSGGAPYYFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKE
TKTQCVRIATKAAATEEPEVIPDPAKQTDRVVKIAGISAGILVFILLLLVVILIVKKSKL
AKKRKDAMGNTRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDQHNFSPRYENHSATAE
SSRLLDVPRYLCEGTESPYQTGQLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEGQS
ASWDVAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPS
HYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTC
VEMEPLAEYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPP
SAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIF
IHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCS
IACLPRNHDKNRFMDMLPPDRCLPFLITIDGESSNYINAALMDSYRQPAAFIVTQYPLPN
TVKDFWRLVYDYGCTSIVMLNEVDLSQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINR
IFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTI
IHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVAL
EYLESS



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