| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 6597 |
Name | SMARCA4 |
Synonym | BAF190|BAF190A|BRG1|MRD16|RTPS2|SNF2|SNF2L4|SNF2LB|SWI2|hSNF2b;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4;SMARCA4;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
Definition | ATP-dependent helicase SMARCA4|BRG1-associated factor 190A|BRM/SWI2-related gene 1|SNF2-beta|SNF2-like 4|brahma protein-like 1|global transcription activator homologous sequence|homeotic gene regulator|mitotic growth and transcription activator|nuclear pr |
Position | 19p13.2 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 51 |
TUSON P-value | 3.83E-09 |
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Pathways and Diseases |
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Pathway | Regulation of retinoblastoma protein;PID Curated;200191 |
Pathway | Regulation of Wnt-mediated beta catenin signaling and target gene transcription;PID Curated;200106 |
Pathway | Glucocorticoid receptor regulatory network;PID Curated;200077 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | chromatin remodeling by hswi/snf atp-dependent complexes;PID BioCarta;100141 |
Pathway | the information processing pathway at the ifn beta enhancer;PID BioCarta;100079 |
Disease | Renal tubular acidosis;FunDO |
Disease | Hereditary disease;FunDO |
Disease | Adrenal gland hyperfunction;FunDO |
Disease | Cancer;FunDO |
Disease | Rhabdoid tumor predisposition syndrome 2;OMIM |
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External Links |
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Links to Entrez Gene | 6597 |
Links to all GeneRIF Items | 6597 |
Links to iHOP | 6597 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>6597 : length: 4944 atgtccactccagacccacccctgggcggaactcctcggccaggtccttccccgggccct ggcccttcccctggagccatgctgggccctagcccgggtccctcgccgggctccgcccac agcatgatggggcccagcccagggccgccctcagcaggacaccccatccccacccagggg cctggagggtaccctcaggacaacatgcaccagatgcacaagcccatggagtccatgcat gagaagggcatgtcggacgacccgcgctacaaccagatgaaaggaatggggatgcggtca gggggccatgctgggatggggcccccgcccagccccatggaccagcactcccaaggttac ccctcgcccctgggtggctctgagcatgcctctagtccagttccagccagtggcccgtct tcggggccccagatgtcttccgggccaggaggtgccccgctggatggtgctgacccccag gccttggggcagcagaaccggggcccaaccccatttaaccagaaccagctgcaccagctc agagctcagatcatggcctacaagatgctggccagggggcagcccctccccgaccacctg cagatggcggtgcagggcaagcggccgatgcccgggatgcagcagcagatgccaacgcta cctccaccctcggtgtccgcaacaggacccggccctggccctggccctggccccggcccg ggtcccggcccggcacctccaaattacagcaggcctcatggtatgggagggcccaacatg cctcccccaggaccctcgggcgtgccccccgggatgccaggccagcctcctggagggcct cccaagccctggcctgaaggacccatggcgaatgctgctgcccccacgagcacccctcag aagctgattcccccgcagccaacgggccgcccttcccccgcgccccctgccgtcccaccc gccgcctcgcccgtgatgccaccgcagacccagtcccccgggcagccggcccagcccgcg cccatggtgccactgcaccagaagcagagccgcatcacccccatccagaagccgcggggc ctcgaccctgtggagatcctgcaggagcgcgagtacaggctgcaggctcgcatcgcacac cgaattcaggaacttgaaaaccttcccgggtccctggccggggatttgcgaaccaaagcg accattgagctcaaggccctcaggctgctgaacttccagaggcagctgcgccaggaggtg gtggtgtgcatgcggagggacacagcgctggagacagccctcaatgctaaggcctacaag cgcagcaagcgccagtccctgcgcgaggcccgcatcactgagaagctggagaagcagcag aagatcgagcaggagcgcaagcgccggcagaagcaccaggaatacctcaatagcattctc cagcatgccaaggatttcaaggaatatcacagatccgtcacaggcaaaatccagaagctg accaaggcagtggccacgtaccatgccaacacggagcgggagcagaagaaagagaacgag cggatcgagaaggagcgcatgcggaggctcatggctgaagatgaggaggggtaccgcaag ctcatcgaccagaagaaggacaagcgcctggcctacctcttgcagcagacagacgagtac gtggctaacctcacggagctggtgcggcagcacaaggctgcccaggtcgccaaggagaaa aagaagaaaaagaaaaagaagaaggcagaaaatgcagaaggacagacgcctgccattggg ccggatggcgagcctctggacgagaccagccagatgagcgacctcccggtgaaggtgatc cacgtggagagtgggaagatcctcacaggcacagatgcccccaaagccgggcagctggag gcctggctcgagatgaacccggggtatgaagtagctccgaggtctgatagtgaagaaagt ggctcagaagaagaggaagaggaggaggaggaagagcagccgcaggcagcacagcctccc accctgcccgtggaggagaagaagaagattccagatccagacagcgatgacgtctctgag gtggacgcgcggcacatcattgagaatgccaagcaagatgtcgatgatgaatatggcgtg tcccaggcccttgcacgtggcctgcagtcctactatgccgtggcccatgctgtcactgag agagtggacaagcagtcagcgcttatggtcaatggtgtcctcaaacagtaccagatcaaa ggtttggagtggctggtgtccctgtacaacaacaacctgaacggcatcctggccgacgag atgggcctggggaagaccatccagaccatcgcgctcatcacgtacctcatggagcacaaa cgcatcaatgggcccttcctcatcatcgtgcctctctcaacgctgtccaactgggcgtac gagtttgacaagtgggccccctccgtggtgaaggtgtcttacaagggatccccagcagca agacgggcctttgtcccccagctccggagtgggaagttcaacgtcttgctgacgacgtac gagtacatcatcaaagacaagcacatcctcgccaagatccgttggaagtacatgattgtg gacgaaggtcaccgcatgaagaaccaccactgcaagctgacgcaggtgctcaacacgcac tatgtggcaccccgccgcctgctgctgacgggcacaccgctgcagaacaagcttcccgag ctctgggcgctgctcaacttcctgctgcccaccatcttcaagagctgcagcaccttcgag cagtggtttaacgcaccctttgccatgaccggggaaaaggtggacctgaatgaggaggaa accattctcatcatccggcgtctccacaaagtgctgcggcccttcttgctccgacgactc aagaaggaagtcgaggcccagttgcccgaaaaggtggagtacgtcatcaagtgcgacatg tctgcgctgcagcgagtgctctaccgccacatgcaggccaagggcgtgctgctgactgat ggctccgagaaggacaagaagggcaaaggcggcaccaagaccctgatgaacaccatcatg cagctgcggaagatctgcaaccacccctacatgttccagcacatcgaggagtccttttcc gagcacttggggttcactggcggcattgtccaagggctggacctgtaccgagcctcgggt aaatttgagcttcttgatagaattcttcccaaactccgagcaaccaaccacaaagtgctg ctgttctgccaaatgacctccctcatgaccatcatggaagattactttgcgtatcgcggc tttaaatacctcaggcttgatggaaccacgaaggcggaggaccggggcatgctgctgaaa accttcaacgagcccggctctgagtacttcatcttcctgctcagcacccgggctgggggg ctcggcctgaacctccagtcggcagacactgtgatcatttttgacagcgactggaatcct caccaggacctgcaagcgcaggaccgagcccaccgcatcgggcagcagaacgaggtgcgt gtgctccgcctctgcaccgtcaacagcgtggaggagaagatcctagctgcagccaagtac aagctcaacgtggaccagaaggtgatccaggccggcatgttcgaccagaagtcctccagc catgagcggcgcgccttcctgcaggccatcctggagcacgaggagcaggatgagagcaga cactgcagcacgggcagcggcagtgccagcttcgcccacactgcccctccgccagcgggc gtcaaccccgacttggaggagccacctctaaaggaggaagacgaggtgcccgacgacgag accgtcaaccagatgatcgcccggcacgaggaggagtttgatctgttcatgcgcatggac ctggaccgcaggcgcgaggaggcccgcaaccccaagcggaagccgcgcctcatggaggag gacgagctcccctcgtggatcatcaaggacgacgcggaggtggagcggctgacctgtgag gaggaggaggagaagatgttcggccgtggctcccgccaccgcaaggaggtggactacagc gactcactgacggagaagcagtggctcaaggccatcgaggagggcacgctggaggagatc gaagaggaggtccggcagaagaaatcatcacggaagcgcaagcgagacagcgacgccggc tcctccaccccgaccaccagcacccgcagccgcgacaaggacgacgagagcaagaagcag aagaagcgcgggcggccgcctgccgagaaactctcccctaacccacccaacctcaccaag aagatgaagaagattgtggatgccgtgatcaagtacaaggacagcagcagtggacgtcag ctcagcgaggtcttcatccagctgccctcgcgaaaggagctgcccgagtactacgagctc atccgcaagcccgtggacttcaagaagataaaggagcgcattcgcaaccacaagtaccgc agcctcaacgacctagagaaggacgtcatgctcctgtgccagaacgcacagaccttcaac ctggagggctccctgatctatgaagactccatcgtcttgcagtcggtcttcaccagcgtg cggcagaaaatcgagaaggaggatgacagtgaaggcgaggagagtgaggaggaggaagag ggcgaggaggaaggctccgaatccgaatctcggtccgtcaaagtgaagatcaagcttggc cggaaggagaaggcacaggaccggctgaagggcggccggcggcggccgagccgagggtcc cgagccaagccggtcgtgagtgacgatgacagtgaggaggaacaagaggaggaccgctca ggaagtggcagcgaagaagactga |
Protein Sequence |
>6597 : length: 1647 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS DSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQ KKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYEL IRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSV RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS RAKPVVSDDDSEEEQEEDRSGSGSEED |